Mike Rea, IDEA Pharma @ideapharma
CEO IDEA Pharma. Pharmaceutical innovation geek. Author, Pharmaceutical Positioning. Senior Fellow @fastercures. *From R&D to RxD* Tweet about clients sometimes ideapharma.com Joined August 2010-
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Spring arrived! Work by the pond meant the dogs could hang, and have fun… Plus a first ride on my new bike at lunchtime - felt amazing
🧵We’ve come to accept a default pre-clinical → phase I → phase II → phase III, etc., view of how things are done around here. And, because of that, and the organisational structures, incentive structures and metrics have sprung up to recognise success linkedin.com/pulse/enemies-…
@ideapharma @JackScannell13 is one of the most interesting minds on the subject of decision quality within pharma and the decline in productivity. This interview focuses on his publications & thoughts around the models we use, and how we could improve decision making podcast.ideapharma.com/episodes/idea-…
@ideapharma We know that, even in pharmaceutical companies who are doing well, launching more than one product a year is unlikely. So, despite keeping it all slow and regular, we’re not achieving safety, while we do know that we’re reining in the speed of the quickest linkedin.com/pulse/one-size…
Serendipity, luck, and planning opportunity The shout of 'Eureka' certainly needs a prepared mind, and a set of questions that make the insight exciting, but it is often said that the most important words in discovery are 'hmm, that's funny' @ideapharma linkedin.com/pulse/serendip…
@ideapharma The difference between invention & innovation can seem pedantic, but the distinction is critical to our biotech industry. Some pharma companies have remarkable pipelines-they're inventive. Others are able to add value to their invention-they're innovative linkedin.com/pulse/pharmace…
@ideapharma One of the fundamental challenges is that a lot of drugs fail because of the question that they're asked in the studies. So, you've got good drugs asked the wrong question in the study, going back on the pile of drugs that probably will never see daylight linkedin.com/pulse/asymmetr…
@ideapharma A time for new questions by Mike Rea: "If you do not change direction, you may end up where you are heading" -Lao Tzu 'Without a plan, 10 men can see no further than one.' linkedin.com/pulse/time-new…
@ideapharma Are companies agile enough to pivot? by Mike Rea The new competitive advantage is in asymmetric learning - learning faster, more creatively and more broadly, what the opportunity for your drug is - not for drugs on average, but for your drug in particular linkedin.com/pulse/companie…
X is a great source of book recommendations - these both look fascinating @TomChivers and @nytdavidbrooks
@ideapharma Great post! On the phase transition success 💯. Since the only thing that actually matters is launch and helping people, back out the expected transition probabilities and compare to actual. For example, in our model a 60% success rate in phase 3 over time in onc = 30% phase 2
I wanted to buy a forcola (a gondola’s oar guide), so came to the workshop of the artisan the gondoliers we spoke to recommended… 👏🏼 Paolo Brandolisio 🙏🏻
Be lucky by design, be serendipitous by planning linkedin.com/pulse/serendip…
Eminence based decision making vs evidence based decision making: the failure of pharma’s PPP model linkedin.com/pulse/being-mi…
What does putting an axe through your foot have to do with pharmaceutical innovation? Enemies of Pharmaceutical Innovation linkedin.com/pulse/enemies-…
We are proud to share that FidoCure, in collaboration with our esteemed veterinary partners, global health leaders, and machine learning experts, have reached a significant milestone by enrolling over 5,000 dogs in our canine cancer treatment platform #FidoCure5000
At my favourite restaurant in the world this evening, in my favourite city on the planet - so simply perfect
Efficiency, effectiveness and productivity in pharmaceutical R&D bit.ly/3UCXKkO This new analysis uses data for a cohort of 14 pharma companies to model ‘snapshot’ views of R&D productivity and assess the impact of productivity levers on a company-by-company basis
Curious to learn more about our First-in-Human Study of BRB-002? Check out our press release here: brbio.com/bitterroot-bio… #BitterrootBio #BRB002 #FirstinHuman #heartdisease #cardiovascular #drugdevelopment
You wonder whether 2024 will have any great records, and then, one Friday, two come along within a couple of minutes of each other 🙏🏻🤘🏻
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@TomChivers @ideapharma @nytdavidbrooks love youre here!!
@Jerry_DurhamPT @ideapharma @nytdavidbrooks hey anyone talking about my books on here gets a thumbs up from me
@TomChivers @ideapharma @nytdavidbrooks I LOVE TWITTER!!!!
@Jerry_DurhamPT @ideapharma @nytdavidbrooks hope you enjoy it!
@ideapharma @JackScannell13 is one of the most interesting minds on the subject of decision quality within pharma and the decline in productivity. This interview focuses on his publications & thoughts around the models we use, and how we could improve decision making podcast.ideapharma.com/episodes/idea-…
@ideapharma We know that, even in pharmaceutical companies who are doing well, launching more than one product a year is unlikely. So, despite keeping it all slow and regular, we’re not achieving safety, while we do know that we’re reining in the speed of the quickest linkedin.com/pulse/one-size…
@ideapharma Innovation, Invention: what matters by Mike Rea linkedin.com/pulse/innovati…
Serendipity, luck, and planning opportunity The shout of 'Eureka' certainly needs a prepared mind, and a set of questions that make the insight exciting, but it is often said that the most important words in discovery are 'hmm, that's funny' @ideapharma linkedin.com/pulse/serendip…
@ideapharma The difference between invention & innovation can seem pedantic, but the distinction is critical to our biotech industry. Some pharma companies have remarkable pipelines-they're inventive. Others are able to add value to their invention-they're innovative linkedin.com/pulse/pharmace…
@ideapharma One of the fundamental challenges is that a lot of drugs fail because of the question that they're asked in the studies. So, you've got good drugs asked the wrong question in the study, going back on the pile of drugs that probably will never see daylight linkedin.com/pulse/asymmetr…
@ideapharma If you have the 5th highest revenue in the pharmaceutical/biotechnology industry, but only 0.5% of that comes from products you have launched in the past 5 years, there is a hard argument to make that you're doing well in any measure of sustainability linkedin.com/pulse/sustaina…
@ideapharma A time for new questions by Mike Rea: "If you do not change direction, you may end up where you are heading" -Lao Tzu 'Without a plan, 10 men can see no further than one.' linkedin.com/pulse/time-new…
@ideapharma Are companies agile enough to pivot? by Mike Rea The new competitive advantage is in asymmetric learning - learning faster, more creatively and more broadly, what the opportunity for your drug is - not for drugs on average, but for your drug in particular linkedin.com/pulse/companie…
@ideapharma @TomChivers @nytdavidbrooks Excellent... Enjoy
Today, I have some big new to announce - we are moving our global headquarters to Boston! In 2014, @InSilicoMeds launched in Baltimore, we then moved to New York and we will still keep a small office at the epic Cure building but our new HQ will be based at 1000 Massachusetts…
Thinking of using historical PTS in predicting future success or valuation? Remember that for phase 1 and 2 especially, it’s the teams’ success that you are measuring, not the molecule. (True for all phases) $xbi