Peter Kolchinsky @PeterKolchinsky
Managing Partner, RA Capital Management. We build & invest in biotech companies. Scientist. Author, The Great American Drug Deal. https://t.co/ARVLrrTQU4 racap.com Boston, MA Joined May 2019-
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IRA’s 9y pill penalty woke up many in biotech to consequences of public’s hatred of pharma, blamed for high OOP costs. Many now seek roadmap for fixing problem at its root. Countless tactics… TBD. The strategy is here: @NPLB_org @IAmBiotech @PhRMA rapport.bio/all-stories/er…
By spinning clinical flu program back out from partner JNJ into itself, Cidara has renewed purpose & becomes first fledgling to take flight from RA Capital’s Project Condor. What’s Condor? More on that, the Cidara deal, & other things w/ bird names & big plans here……
Ensuring biomedical progress takes more than wonky policy solutions. @PeterKolchinsky @rapport_bio makes vital case for biotech to "engage our customers & inspire them to preserve the affordable innovation framework that will ultimately also scale breakthrough medication access…
Ensuring biomedical progress takes more than wonky policy solutions. @PeterKolchinsky @rapport_bio makes vital case for biotech to "engage our customers & inspire them to preserve the affordable innovation framework that will ultimately also scale breakthrough medication access…
🇺🇸 🇹🇼 🇺🇦 🇮🇱
Great @steveusdin1 commentary: "The point of accelerated approval is not perfection; it’s to allow risk-taking when there’s evidence that a therapy is reasonably likely to benefit patients who are suffering from a serious condition."
Great @steveusdin1 commentary: "The point of accelerated approval is not perfection; it’s to allow risk-taking when there’s evidence that a therapy is reasonably likely to benefit patients who are suffering from a serious condition."
Thanks for elevating, Daphne. What I'm seeing in the comments is people reacting to what they think is unfair but trying to apply legal arguments. We cover the legal arguments in the article... but we don't defend the practice on the basis of its legality. It is legal, that's…
Thanks for elevating, Daphne. What I'm seeing in the comments is people reacting to what they think is unfair but trying to apply legal arguments. We cover the legal arguments in the article... but we don't defend the practice on the basis of its legality. It is legal, that's…
In honor of Patriots’ day (a festive New England thing), Sarah Reed and I put out a piece on Private Investments in Patriotic Equities (PIPEs) and confidential disclosure of data. rapport.bio/all-stories/ob…
US support for Israel’s security must be immediate & ironclad. The president is doing the right thing. Mr Speaker: your turn. Come back from Mar-a-Lago and put the Israel & Ukraine bill on the floor on Monday.
Once again, plain english of how insurance and innovation are supposed to work together. Truth in insurance is good policy. Good to see it being discussed in Congress. @NPLB_org @IAmBiotech @PhRMA @TheEconomist @BioCentury
Once again, plain english of how insurance and innovation are supposed to work together. Truth in insurance is good policy. Good to see it being discussed in Congress. @NPLB_org @IAmBiotech @PhRMA @TheEconomist @BioCentury
Exactly. When insurance says they cover something, that should mean that it’s affordable to the patient. If they can’t afford it, then insurance wasn’t honest about covering it. This is the right discussion for Congress to be having. @NPLB_org @IAmBiotech @PhRMA @TheEconomist
Exactly. When insurance says they cover something, that should mean that it’s affordable to the patient. If they can’t afford it, then insurance wasn’t honest about covering it. This is the right discussion for Congress to be having. @NPLB_org @IAmBiotech @PhRMA @TheEconomist
Small companies would absolutely not be able to get seed funding if we had to believe that the ONLY way to generate a return would be to build it into a profitable standalone company. That takes critical mass. Pharma already has it. Wasteful not to make use of it.
Small companies would absolutely not be able to get seed funding if we had to believe that the ONLY way to generate a return would be to build it into a profitable standalone company. That takes critical mass. Pharma already has it. Wasteful not to make use of it.
Movie studies don’t need to charge for movies because they aren’t even ones who write scripts… and writers who do barely earn anything. So don’t worry about price controlling movies. Hollywood will still remain creative. Sound dumb? It is. Wapo is smarter than this but thinks…
Indeed, failure of society to harvest the benefits of the biotech social contract… specifically failure to make PBMs make good use of what the FDA and industry delivered (biosimilars). Several fixes… but contractual genericization is probably easiest. @NPLB_org
Indeed, failure of society to harvest the benefits of the biotech social contract… specifically failure to make PBMs make good use of what the FDA and industry delivered (biosimilars). Several fixes… but contractual genericization is probably easiest. @NPLB_org
Pharmas now attempting to “negotiate” with CMS. During M&A discussion, sides can point to NPV assumptions to argue for particular share prices. Equivalent for a drug price is a GCEA, which estimates societal value of a drug. You know NPV… do you know GCEA? More on that at…
NPLB applauds new "Zero Copay" health plan mandate to prioritize the health & well-being of all insured Americans. The FTC will require all health plans to charge zero copays for prescribed medicines or face dissolution. Read the full announcement here: nopatientleftbehind.docsend.com/view/bur6s3n6q…
The @FTC has finally called insurance out for false advertising. Indeed, if you say you offer health insurance, you can’t then put appropriate treatment out of reach with high out of pocket costs. Good work, @NPLB_org nopatientleftbehind.docsend.com/view/bur6s3n6q… @IAmBiotech @PhRMA @Aetna @Humana
After slight delay due to market downturn, RA Capital is proud to unveil its long planned suite of biotech ETFs to democratize biotech investing. We can make cures as long as policy doesn’t undermine. We need insurance reform, not price controls. prnewswire.com/news-releases/…
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@otariiman @PeterKolchinsky Before “CSI”, did anyone think that crime scene work—especially “science-y” sorts of stuff—could get cultural traction?
@otariiman @PeterKolchinsky I think you have to get out of your mindset of “data” and “sources” for these sorts of questions. These are social/marketing questions, so are “soft” by their nature. That said, biopharma has not done much collectively to address public concerns.
@otariiman @PeterKolchinsky For example, I would love to see movies or TV shows about “drug hunters”. Seems impossible, but if it can be done—and not just a one-off, it’s the sort of thing that can shift the zeitgeist.
@daphnezohar @PeterKolchinsky Thanks for posting. I haven’t read an article that got me thinking so much in a long time. That is a very nice piece of work by @PeterKolchinsky
Peter offers an insightful commentary in @rapport_bio today to tackle the question of affordable-innovation and global access for blockbuster medications -- largely using Trikafta as an example -- and importantly concludes the public's eroding tolerance for "high priced" drug…
Every new blockbuster erodes public's tolerance for "high" prices (e.g. PDABs, price controls), decreasing other biotechs' chances at success. Here's roadmap for restoring tolerance & inspiring. No half-heroes. @MassBio @IAmBiotech @PhRMA @NPLB_org rapport.bio/all-stories/er…
Spent time w/ other biotech CEOs this week and it struck me how much humility this industry teaches its leaders. Even successes are viewed through a lens of learning rather than arrogance. “Every new medicine that makes it to patients is a little miracle”
Great @steveusdin1 commentary: "The point of accelerated approval is not perfection; it’s to allow risk-taking when there’s evidence that a therapy is reasonably likely to benefit patients who are suffering from a serious condition."
Drive-by analysis of accelerated approval is intellectual malpractice biocentury.com/article/652132…
US support for Israel’s security must be immediate & ironclad. The president is doing the right thing. Mr Speaker: your turn. Come back from Mar-a-Lago and put the Israel & Ukraine bill on the floor on Monday.
This whole thing works well as a relay race. Academics discover mechanisms -> entrepreneurs translate into candidates -> biopharma validates in the clinic -> pharma scales marketing & distribution. With each handoff returning a 10x reward to the prior team for risk and effort.
Small companies would absolutely not be able to get seed funding if we had to believe that the ONLY way to generate a return would be to build it into a profitable standalone company. That takes critical mass. Pharma already has it. Wasteful not to make use of it.
@Avik @PeterKolchinsky Surely, @Avik, you don’t believe that small companies could raise as much money if investors did not think they could be sold at a premium— sometimes for drugs that will never even be approved.
@PeterKolchinsky If insurance is not insurance, how healthcare can function? Politicians just want to turn medicine to a public health policy exercise. This model worked when the intervention was fucking “sanitation”. It doesn’t work in the world where we understand biology
Food allergies not funny. Where does the line between humor and harm lie? Girl purposely slapped in face w/ hand covered in peanut butter at school- went to hospital Words of jest easily turn into actions -read my piece allergicliving.com/2024/04/04/opi… It's time for us to recognize the…
I started getting the biotech investing bug March 2012 @PeterKolchinsky
We launch, today, with our investigation of UWM. UWM says independent mortgage brokers "shop dozens of lenders" to find the "best deal." But the nation's biggest lender pressures those brokers to push deals its way. Hunterbrook found $39 billion in mortgages came from brokers…
WHO's on first? What's on second? Why is RA Capital pooping on April Fool's day? Boundless Bio, the Supreme Court & mifepristone, FDA's CRLs for failing to launch confirmatory trials. And more on @BioCentury 's podcast. Listen at biocentury.com/article/651937. @PeterKolchinsky
@RACapital launches a panoply of ETFs covering the biotech space on this very April 1st. Hats off to @PeterKolchinsky and team on making it so much easier to invest in this critical sector. At first I contemplated, this must be a shenanigan, and so was surprised when my purchase…
After slight delay due to market downturn, RA Capital is proud to unveil its long planned suite of biotech ETFs to democratize biotech investing. We can make cures as long as policy doesn’t undermine. We need insurance reform, not price controls. prnewswire.com/news-releases/…
“The RABB Indifferent to Technology fund variant focuses on the untapped value of "vaporware" programs that will never be developed” Best April Fools prank I’ve seen, ever
After slight delay due to market downturn, RA Capital is proud to unveil its long planned suite of biotech ETFs to democratize biotech investing. We can make cures as long as policy doesn’t undermine. We need insurance reform, not price controls. prnewswire.com/news-releases/…
👏👏👏 I lost it here, well done @PeterKolchinsky 🤣 "The actual rabies virus is nothing compared to the godforsaken instrument of horrors y'all are unleashing on the world," said Mario Barro, yet another virologist on the RA Capital team ("the only real one", who actually…
After slight delay due to market downturn, RA Capital is proud to unveil its long planned suite of biotech ETFs to democratize biotech investing. We can make cures as long as policy doesn’t undermine. We need insurance reform, not price controls. prnewswire.com/news-releases/…
"Feral" Trade Commission Slow clap
The @FTC has finally called insurance out for false advertising. Indeed, if you say you offer health insurance, you can’t then put appropriate treatment out of reach with high out of pocket costs. Good work, @NPLB_org nopatientleftbehind.docsend.com/view/bur6s3n6q… @IAmBiotech @PhRMA @Aetna @Humana
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