Persimmon Tree Investments @PersimmonTI
“The fault, dear Brutus, lies not within the stars, but in ourselves, that we are underlings.” Joined December 2015-
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Followers8K
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Following180
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Likes10K
@PersimmonTI @Persimmon_Plus You aren’t seriously charging 200$ just for you to guess (and be wrong) on a new buyout every Monday are you?
$DCPH — ONO wanted the kit and caboodle…
$DCPH — ONO wanted the kit and caboodle…
$XBI And we have an acquisition — with the final pick of the 2024 draft, ONO selects $DCPH, for $2.4 billion:
$XBI And we have an acquisition — with the final pick of the 2024 draft, ONO selects $DCPH, for $2.4 billion:
$MOR $NVS $XBI Regarding the pelabresib P3 in myelofobrosis and the apparent imbalance in treatment arms of observed AML onset (6 on pela v. 3 on control thus far), it looks like there is literature supportive of the hypothesis that pelabresib, as a BET inhibitor, could spur a…
$MOR $NVS $XBI Regarding the pelabresib P3 in myelofobrosis and the apparent imbalance in treatment arms of observed AML onset (6 on pela v. 3 on control thus far), it looks like there is literature supportive of the hypothesis that pelabresib, as a BET inhibitor, could spur a… https://t.co/PPCMZp0bKm
$RHHBY $JANX $XBI Still think that $JANX is taken out by Roche in the near term. Conference call indicates interest in adding assets to pipeline by acquisition, oncology is one area of interest, and $JANX TCEs seem to be at that point of having some early POC of the science,…
$RHHBY $JANX $XBI Still think that $JANX is taken out by Roche in the near term. Conference call indicates interest in adding assets to pipeline by acquisition, oncology is one area of interest, and $JANX TCEs seem to be at that point of having some early POC of the science,… https://t.co/PjEyCTVRaV
$AMZN Fallout Have been enjoying Amazon/MGM’s Fallout — under the weight of heavy expectations, it… succeeds, in my view. Melding the lore of the video game into an ensemble storyline, the show deftly amplifies the “classic” dystopian fable angle, with some commentary about…
$CYTK CFO leaves — definitely no M&A New CFO joins — definitely no M&A Seems legit.
$XBI @BiotechCH diversifying the discussion yesterday to include topics of general business import, including capital gains tax rates and possible taxation of unrealized gains (the less said about this abomination, the better), and also: FTC rule banning non-competes……
$MREO Not much to update from my end on $MREO, but such as there is will be on the Plus..
Sorry, but why one would ever short $VKTX is beyond me… Or $PFE (at these levels) for that matter…
Sorry, but why one would ever short $VKTX is beyond me… Or $PFE (at these levels) for that matter…
$XBI Folks, never fall in love with a stock. It won’t ever love you back. Data, management, execution, cash. No? Then, no.
$CYTK Ok, ok… some more useless thoughts about $CYTK coming up at some point. Nice to see that they have a CFO in place.
“ $PFE should wrap up their purchase of $VKTX this weekend in prep for upcoming quarterly earnings call this week”
Adam Feuerstein ✡�.. @adamfeuerstein
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5 Followers 31 Following Here to call out dumb things in biotech - of which there are so very many. Views are my own. If you trade off the back of them that's your faultRAJ @rajrunga
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8K Followers 509 Following Healthcare buyside. ECM, event driven and long term investments.@PersimmonTI @Persimmon_Plus You aren’t seriously charging 200$ just for you to guess (and be wrong) on a new buyout every Monday are you?
@PersimmonTI $MOR on their corp deck: '[MET inhibition] helps restore the balance of cells in the bone marrow'. yup.
Impressive strength, you can't tell he had #DMD $SRPT Elevidys make DMD kids' dreams come true!
I’ll take the under
Robotaxis will generate 8-10 Trillion in revenues in 2030, half of which will go to platforms like Tesla $TSLA says Cathie Wood
$DCPH to be Acquired by ONO Pharmaceutical For $2.4 Billion. $ONO Deciphera Shareholders to Receive $25.60/share Cash
Destiny breast 06. Shows PFS benifit in both Her2 low and Her2 ultra low in MBC in second line onwards . Os awaited. T-DXd is soon going to be used irrespective of her2 status.
Still not as bad as some of the stock market takes I’ve had over the years
Know I've said it before, but a rough biotech market certainly teaches me to take the dips less seriously Just focusing on my process & the "controllables"
Multiple Pharma materially shrinking their pipelines ( $RHHBY $SANY $BMS most recently) Killing stuff that won’t work is good for returns, but unless PTS rises smaller pipelines won’t plug future LOEs More acquisitions coming therefore?
@PersimmonTI Will give another shot- first episode wasn't bad at all
Immune checkpoint inhibitors, like anti-PD-1 and anti-CTLA-4, are effective against cancer, but not all patients respond How could the response be improved? Here's an idea from this week's issue of Science Giampazolias et al. found that feeding mice a diet high in vitamin D…
Bispecific T cell engagers (BiTEs) recruit T cells to target cells - usually B cells, in cancer - to deplete the targets This study repurposed BiTEs for rheumatoid arthritis, an autoimmune condition driven by B cells It's a small, single arm study of 6 patients, who had…
I'm best man at my buddy's second wedding. Is it appropriate to open my dinner speech with “Welcome back everyone"?
Our CEO @daphnezohar joined @eDougBanks @BarryGreene @sharcunningham & Mike Nally on the main stage @MassBio's #StateofPossible2024 for the Success in Choppy Waters panel. It was an inspiring day w/the local bio community discussing ways we can collectively move medicines forward
$lptx $gild cd47 magrolimab crc trial discontinued... Gild knows the crc market and has experience. Strategic investment in leap potentially making even more sense. Dkn-01 randomized crc trial 8 months in and increasing enrollment classic.clinicaltrials.gov/ct2/show/NCT05…
$gild cd47 Magro officially kaput fiercebiotech.com/biotech/gilead…
In biotechs I have this iron clad rule- if you want to buy after a big positive catalyst just wait. It will almost always retrace deep into the gap with time. Seen it over and over again countless times. $IMVT