Drugs @drug_smolecules
☣Femtomolar potency poems and limericks ☣Oceanic Boundlessness (p=0.0001) North America Joined January 2016-
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$dcph higher market cap than $tgtx!!!
This CD19 revival reminds me of $VERA Atacicept around for a long time. Small trial with idiosyncratic (and ultimately just unlucky) tox signals caused pessimism and doubt about utility. Inebilizumab likely a very good therapy, but pigeon holed early. $elym $cgem
Why is the "actual study completion date" December 2022? It took 2.5 years to publish this?
Hmmm... ✅ ❔ ✅ ✅
Wow. Marc Tessier-Lavigne, who resigned as @Stanford president this summer for overseeing labs that produced falsified research at 3 different institutions over 20 years, returns to biotech with $1bn in funding.
Wow. Marc Tessier-Lavigne, who resigned as @Stanford president this summer for overseeing labs that produced falsified research at 3 different institutions over 20 years, returns to biotech with $1bn in funding.
Late, but I think we are making major autoimmune breakthroughs now. Renal revival: Yes, kdny and alpn gone No real new targeted onc successes unless you count mrtx PRMT5, which I expect to disappoint No murders
Late, but I think we are making major autoimmune breakthroughs now. Renal revival: Yes, kdny and alpn gone No real new targeted onc successes unless you count mrtx PRMT5, which I expect to disappoint No murders
CBER head Peter Marks noting at @StrengthenFDA that the dialing back around gene therapies is being exacerbated by these challenges
$DAWN receives approval for Pediatric LGG
In biggest-ever bet on using AI to design drugs, biotech heavyweights launch Xaira with $1B+ in backing - massive from @AndrewE_Dunn and @RLCscienceboss endpts.com/in-biggest-eve…
I propose to you the worst timed (significant) insider purchase. Either that or the market thinks Insider buys are bearish. $FULC
I propose to you the worst timed (significant) insider purchase. Either that or the market thinks Insider buys are bearish. $FULC https://t.co/lEDqKz04IA
Adam Feuerstein ✡�.. @adamfeuerstein
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10K Followers 1K FollowingDan Rosenblum @sharkbiotech
23K Followers 1K Following Trading with the sharks at sharkinvesting since 1999 . Writing about biotech since 2006.Jing Liang 🇺🇦 @AppleHelix
8K Followers 4K Following Entrepreneur. Drug hunter. Novice biotech scripophile. Anti-ideologues. Proudly blocked by @VPrasadMDMPH. https://t.co/zMzJBoov2VBruce Booth @LifeSciVC
50K Followers 731 Following Early stage biotech VC. Recovering scientist. Opinions expressed are solely my own and do not express the views or opinions of Atlas Venture.dough @semodough
37K Followers 569 Following BIOTECH man LONGTERM FOCUS many positions-also trade around my CORE holdings my opinion only do your own research with meGoose Data (wa/wa) @GooseData
4K Followers 201 Following Biotech visionary. Looking for best drugs with goose data. Retweets mean honking endorsement.Keith Hornberger @KRHornberger
11K Followers 288 Following Exec. director, medicinal chemistry @ArvinasInc | PhD @Columbia | hiker | beer & cocktail enthusiast | he/him/huz/dad | dreaming of @SedonaAZ | all posts my ownAdam May @A_May_MD
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29 Followers 107 Following Med Chem PhD, biotech investment analyst. Small molecules can do so much more than sit in an protein's active site.@drug_smolecules - CX-904 (masked EGFRxCD3 Probody® T-cell engager) preliminary Phase 1a results to be presented from ongoing dose escalation study - - Management to hold conference call at 5 p.m. EDT / 2 p.m. PDT on May 8th- $CTMX
$MRK Phase 3 KEYNOTE-811 Trial Met Dual Primary Endpoint of OS as First-Line Treatment in Patients With HER2-Positive Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
@drug_smolecules Not meant at anyone in particular but seems that hit a spot
@Leo09416981 @BiotechElmo CD19 CAR-Ts are literally curative in grade 3/4 LN. Hard to be excited about voclosporin or for that matter Gazyva without comparable efficacy.
@drug_smolecules AI wasn’t advanced enough to write the article until now
$adxn fail 😫 $adxn globenewswire.com/news-release/2…
Sunday story from me. Important enough not to wait for Monday. $MOR $NVS New, serious safety risk related to MorphoSys’ cancer drug complicates, potentially threatens, Novartis acquisition statnews.com/2024/04/28/mor…
@drug_smolecules @Bakery_bros @jesse_brodkin Via SPAC!
@Bakery_bros No journal has more unreproducible behavioral data, in my experience.
😮💨
Which of the following ADC payloads is more potent?
@drug_smolecules @OxAnalyst Never. the worst were hamsters. they are so damn cute - felt awful working with them
I previously wrote about the PK/PD/efficacy framework here in the context of the free drug hypothesis.
$BMY overpaid. KRAS landscape changing rapidly.
@BruceJohns4207 It's ethical to randomise to standard-of-care chemo, yes.
@BertrandBio Two coincidences in a day for $RHHBY
And a somewhat ironic $RHHBY pan-RAF inhibitor discontinuation in light of yesterday's $DAWN approval x.com/apexonco/statu…
At Genentech, where he served as chief scientific officer, Tessier-Lavigne took steps to hide fraud in blockbuster Alzheimer’s research being promoted by the company while it sold itself to Roche, according to nine people involved at the time. stanforddaily.com/2023/02/17/int…