IntAct at EBI @intact_project
The Molecular Interactions Database at the EMBL-EBI. Open Source Framework for Molecular Interactions. Also follow➡️@complexportal. ebi.ac.uk/intact Cambridge, UK Joined May 2009-
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IntAct at EBI retweeted
In our next release (2025_04) we will deploy a new Reference Proteome selection pipeline with the aim of improving the representation of species biodiversity in UniProtKB. Read our blog post to find out how this might affect your research: insideuniprot.blogspot.com/2025/06/captur…
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IntAct at EBI retweeted
🧠 Ever wonder how your tongue detects umami or sweetness? 🧂 Umami is sensed by a GPCR made of TAS1R1 + TAS1R3; sweet by TAS1R2 + TAS1R3. 🍜 Both trigger gustducin proteins, sending signals to your brain (and beyond). 🔬 Learn more: Complex Portal: tinyurl.com/ymd4ews9
IntAct at EBI retweeted
Complex Portal release 251 is out! 5,190 manually curated biological complexes. ebi.ac.uk/complexportal/… (in sync with UniProt release 2025_03)
Excited to share the global proximity interactome in the Human Macroautophagy Pathway! (See: tinyurl.com/bdfaeztn) Study uncovers novel role of OSBPL family lipid transport proteins as new players in autophagy.See IntAct: tinyurl.com/34ksav36 #Macroautophagy #BrumellLab
Excited to share the global proximity interactome in the Human Macroautophagy Pathway!(PMID: 34524948). Study uncovers novel putative connections including the OSBPL family lipid transporters, new players in autophagy.See IntAct: tinyurl.com/34ksav36 #Macroautophagy#BrumellLab
IntAct at EBI retweeted
Want to learn more about macromolecular complexes? Register for our webinar on 𝗝𝘂𝗹𝘆 𝟵𝘁𝗵, 𝟮𝟬𝟮𝟱! Discover more about our latest updates including the Complex Navigator & the integration of ML-predicted complexes (huMap3.0 & MuSIC). ➡️ Register:tinyurl.com/bdy6wttv
IntAct at EBI retweeted
UniProt is a world-leading, freely accessible data resource that provides protein sequence and functional information to scientists worldwide. So what is the value of UniProt for the global scientific community? #FAIRdata #Bioinformatics
UniProt is a world-leading, freely accessible data resource that provides protein sequence and functional information to scientists worldwide. So what is the value of UniProt for the global scientific community? #FAIRdata #Bioinformatics
IntAct's dataset of the month features 75 cancer-associated missense variants in retinoblastoma tumor suppressor protein (PMID:39938803). Visit IntAct & explore detailed expert-curation of variants, binding domains and biophysical parameters (tinyurl.com/4rsx8754). #Cancer
IntAct at EBI retweeted
Now published in @MolSystBiol embopress.org/doi/full/10.10…
IntAct at EBI retweeted
May is skin cancer awareness month! We're highlighting Telomerase holoenzyme complex (CPX-265) featuring TERT(UniProt:O14746). See the complex in tinyurl.com/mt7u4wbs & visit UniProt for all melanoma-associated proteins tinyurl.com/mryjvyu7 #MelanomaAwareness, #SunSafety🧴
It is Skin Cancer awareness month! Explore manually curated interactomes of proteins associated with familial melanoma in IntAct. Access the network in IntAct (tinyurl.com/26tc7xtm). #IntAct_EBI, #ComplexPortal, #UniProt, #MelanomaAwareness, #SunSafety, 😎📷🧴
Thrilled to announce that the protein–protein interactions of 396 SLC transporters, from the RESOLUTE project, is now integrated into IntAct! Congratulations to #Superti-FurgaLab, #FabianFrommelt Explore the interactome at ebi.ac.uk/intact/search?…
Excited to have integrated data from ‘Systematic discovery of mutation-directed neo-protein-protein interactions in cancer’ in IntAct (PMID: 35512704). #tumor #PPI #mutations Explore the interactome at ebi.ac.uk/intact/search?…
IntAct is expanding its Inflammatory Bowel Disease dataset (lnkd.in/ejkr8tKx)! Our latest addition is the lncRNA GATA6-AS1 interactome, from K.E. Sosnovski et al. (2023) in Caco-2 cells (lnkd.in/eiYaFSdK). ➡️ Learn more about this! (lnkd.in/e2RSQEZZ)
IntAct release 250 is out! 1,702,367 binary interactions from 23,612 manually curated publications ebi.ac.uk/intact/about#s… (in sync with UniProt release 2025_02)
IntAct at EBI retweeted
Interested in RASopathy and RAS-driven cancers? This month we feature SHOC-MRAS holophosphatase complexes.....CPX-25716, CPX-25719, CPX-25720. Visit the Complex Portal to learn more!
IntAct at EBI retweeted
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.
IntAct at EBI retweeted
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two members of the IntAct team.
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