Jishnu Das @jishnu1729
Asst Prof - Univ of Pittsburgh SOM (https://t.co/QXxIOm00Zv). Systems immunologist. Views world as networks at different scales. 'Transformed' engineer. Avid reader. jishnulab.org Pittsburgh, PA Joined August 2013-
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Thank you very much @naturemethods for this Research Highlight describing our new interaction language model, SWING, that learns the lexicon of protein and peptide interactions. nature.com/articles/s4159…
Thank you very much @naturemethods for this Research Highlight describing our new interaction language model, SWING, that learns the lexicon of protein and peptide interactions. nature.com/articles/s4159…
Read the Research Briefing on SWING, here! nature.com/articles/s4159…
Read the Research Briefing on SWING, here! nature.com/articles/s4159…
Pittsburgh group presenting at the 19th International Workshop on Scleroderma Research! @PittRheum @PittDeptofMed @jishnu1729
Thanks a lot @naturemethods for highlighting SWING, a generalizable biologically-inspired interaction #language_model that learns that lexicon of peptide and protein interactions & the impact of #genetic #variation on these interactions. #ML
Thanks a lot @naturemethods for highlighting SWING, a generalizable biologically-inspired interaction #language_model that learns that lexicon of peptide and protein interactions & the impact of #genetic #variation on these interactions. #ML
Today in @naturemethods, we define a new lexicon for protein/peptide interactions. SWING is a generalizable zero-shot interaction #language_model that outperforms pLMs in multi-context predictions of the impact of genetic variation on interactions. #ML nature.com/articles/s4159…
For CSI COSI, I am very thankful to my co-chair @jishnu1729 and steering committee @YuriPritykin , @haticeulku, Aly Azeem Khan. And everyone who submitted their for consideration for this session iscb.org/ismbeccb2025/p…
I came to the US in 2010 as a PhD student & it transformed my life. Privileged to lead (since 2020) a #systems #immunology lab comprising an incredible group of men & women. This country gave me opportunities I couldn't have dreamed of elsewhere. Proud #US citizen. Happy 4th all!
Check out our recent review in @MolTherapy about how machine learning approaches enable the discovery of therapeutics across domains cell.com/molecular-ther…. We cover a range of #ML techniques with wide applications to #cellulartherapy.
Check out our recent paper in @JCI_insight where we use interpretable #ML to uncover signatures of pathogenesis in localized #scleroderma (#morphea). insight.jci.org/articles/view/…
Thank you @JCI_insight for highlighting our collaborative work with @corrine_kliment using interpretable #ML approaches to uncover a novel role for GSN in #COPD. We used a range of approaches including a recent flagship method from our lab - SLIDE (nature.com/articles/s4159…).
Thank you @JCI_insight for highlighting our collaborative work with @corrine_kliment using interpretable #ML approaches to uncover a novel role for GSN in #COPD. We used a range of approaches including a recent flagship method from our lab - SLIDE (nature.com/articles/s4159…).
If you're at @ASTMH #TropMed24 do add our Systems Immunology of Tropical Diseases symposium (138) to your schedule for Sat Nov 16th. Speakers include @nadegenziza, Dr Elizabeth Aitken & my co-chair @jishnu1729. Exciting talks across AI/ML, Malaria, TB & NTDs incl Schistosomiasis.
Thank you @CellReports for highlighting our work showing how #protein #networks with structural resolution can identify #immunomodulatory variants in infectious disease. Key coding variants often missed by conventional #GWAS can be picked up by our approach.
Thank you @CellReports for highlighting our work showing how #protein #networks with structural resolution can identify #immunomodulatory variants in infectious disease. Key coding variants often missed by conventional #GWAS can be picked up by our approach.
Uncovering cell-type-specific immunomodulatory variants and molecular phenotypes in COVID-19 using structurally resolved protein networks dlvr.it/TG1HSf
Super fun collaboration with @poholeklab now out in Nature Immunology - nature.com/articles/s4159… . We use interpretable #machine_learning to help identify spatial microniches of IL2 in a murine model of allergic #asthma.
Super fun collaboration with @poholeklab now out in Nature Immunology - nature.com/articles/s4159… . We use interpretable #machine_learning to help identify spatial microniches of IL2 in a murine model of allergic #asthma.
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Study from my lab out today in @ScienceTM - using interpretable #ML on deep #antibody profiles, we uncover mechanisms of schistosomiasis pathogenesis. Collaborative work with @anisircar & @Fairley_NTD. Co-led by @TrirupaChakrab2 & Anushka Saha. science.org/doi/10.1126/sc…
Great to see this out today in @ScienceTM! Collaborative work with @jishnu1729 at Pitt & @Fairley_NTD at Emory and collaborators at CDC & in Brazil. Led by Anushka (@CoulterBME alum) in my lab & @TrirupaChakrab2 at Pitt. Antibody-omics for schistosomiasis diagnostics & beyond 👇
Congratulations to all awardees especially to our own @Niranjana89 !
Congratulations to all awardees especially to our own @Niranjana89 !

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40K Followers 2K Following High-quality basic and translational research representative of all biomedical specialties and physician-scientists. Bluesky: https://t.co/Kz22hHNYOU
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Rahul Satija @satijalab
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151K Followers 1K Following Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.
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Science Translational... @ScienceTM
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