Joel Wong @joelwwh
Scientist @ A*STAR Singapore. Previously: PhD @ Harvard University #microbiome #diet #cancer #phages Joined July 2009-
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Following220
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Joel Wong retweeted
Out Now! A call for caution in the biological interpretation of viral auxiliary metabolic genes bit.ly/4patECC #Virology #Metagenomics #AuxiliaryMetabolicGenes
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Joel Wong retweeted
1/13 🧵 Today, Bindcraft was published in @Nature , one of the most famous AIs in biology for designing protein–protein interactions (PPI). In my opinion. Bindcraft represents one of the most important advances in the post–AlphaFold2 era.
Joel Wong retweeted
Applying ecological principles to microbiome engineering | Nature Microbiology nature.com/articles/s4156…
Joel Wong retweeted
Out Now! Intraspecies warfare restricts strain coexistence in human skin microbiomes bit.ly/4lClWyx #Microbiology #SkinMicrobiome #HumanHealth
Joel Wong retweeted
New online! The human skin microbiome: from metagenomes to therapeutics nature.com/articles/s4157…
Joel Wong retweeted
New online! Lactobacilli biology, applications and host interactions nature.com/articles/s4157…
Joel Wong retweeted
Emerging research suggests a complex interaction between the gut microbiome and endometriosis Here's what you need to know: gutmicrobiotaforhealth.com/the-link-betwe…
Joel Wong retweeted
⭐️Thrilled to share our latest publication! We found that GLP-1 receptor agonists, commonly used for diabetes and weight loss, are associated with the development of small intestinal bacterial overgrowth and intestinal methanogen overgrowth🦠 #GITwitter journals.sagepub.com/doi/10.1177/26…
Joel Wong retweeted
Updating the risks of sugar-sweetened beverages, processed meat and trans fatty acids for Type 2 diabetes, colon cancer and heart disease @NatureMedicine nature.com/articles/s4159… nature.com/articles/s4159…
Joel Wong retweeted
How gut inflammation can induce brain inflammation nature.com/articles/s4158… @Nature
Joel Wong retweeted
The unintended consequences of a gut microbiome transplant cell.com/cell/abstract/…
Joel Wong retweeted
If you care about your microbiome, limit alcohol. Alcohol misuse triggers a vicious cycle of: 📉 Disrupted gut microbiome 🔥 Neuroinflammation via the gut-brain axis 💥 Increased cravings, depression, and anxiety
Joel Wong retweeted
How the gut microbiome could be useful as a biomarker for colon cancer screening nature.com/articles/s4159…
Joel Wong retweeted
Introducing the world's first reasoning model in biology! 🧬 BioReason enables AI to reason about genomics like a biology expert. A thread 🧵:
Joel Wong retweeted
Not all commensal microorganisms shape cancer outcomes in the same way Where are we on the role of microbiome in tumour initiation and progression, interactions with chemotherapy, radiotherapy and targeted therapies? @NatMetabolism nature.com/articles/s4225…
Joel Wong retweeted
To restore the gut microbiome after antibiotics, the right diet (rich in carbohydrates, low in fat) was a better approach than fecal microbial transplants (in the experimental model) nature.com/articles/s4158… nature.com/articles/d4158…
Joel Wong retweeted
The brain can also influence the microbiome Mouse findings show that modulation of hypothalamic circuits can rapidly alter gut microbiota composition: loom.ly/W5jVSHA
Joel Wong retweeted
Read our latest Review for recent and compelling examples of #microbiome based interventions that are ripe for clinical adoption, and discussion of challenges and opportunities facing the field. @gilbertjacka @CMIdigest nature.com/articles/s4159…
Joel Wong retweeted
Microbiome–metabolome dynamics associated with impaired glucose control and responses to lifestyle changes | Nature Medicine nature.com/articles/s4159…
Joel Wong retweeted
If you use Kraken for profiling microbial/environmental/ancient metagenomic data, check this preprint where I benchmark filtering strategies of Kraken output on simulated microbial and environmental metagenomic samples, and provide recommendations for optimal filtering thresholds
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