Jonas (josch1@bsky) @josch_f
Phenoscaping @IHB_research. Previously @treutleinlab @ETH and @zellergroup @EMBL josch.xyz Joined June 2017-
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All researchers should fight against this. Every week I try to persuade my students that top papers often have few quantitative results. With work that's new, important, and clearly qualitatively different (zero to one!), you don't need quantitative results. Demos not tables!
All researchers should fight against this. Every week I try to persuade my students that top papers often have few quantitative results. With work that's new, important, and clearly qualitatively different (zero to one!), you don't need quantitative results. Demos not tables!
From cell lines to full embryos, drug treatments to genetic perturbations, neuron engineering to virtual organoid screens — odds are there’s something in it for you! Built on flow matching, CellFlow can help guide your next phenotypic screen.
From cell lines to full embryos, drug treatments to genetic perturbations, neuron engineering to virtual organoid screens — odds are there’s something in it for you! Built on flow matching, CellFlow can help guide your next phenotypic screen.
Really happy about that one! Also massive thanks to @dbobrovskiy_, who was essential to kick-start the project on our end.
Really happy about that one! Also massive thanks to @dbobrovskiy_, who was essential to kick-start the project on our end.
Excited to have the opportunity to present our latest results at the #cshl2024brain meeting and get valuable feedback! Stay tuned for our bioRxiv preprint coming out soon! @TreutleinLab #cshlbrain #oragnoids #singlecell #quadbio
@zhisong_he, L Dony & @josch_f present🧠#organoids as tools to study brain development, evolution and disease. Just published in @NaturePortfolio as part of the #HumanCellAtlas #HCA2024NatureCollection Congrats to all authors! @GrayCampLab
@zhisong_he, L Dony & @josch_f present🧠#organoids as tools to study brain development, evolution and disease. Just published in @NaturePortfolio as part of the #HumanCellAtlas #HCA2024NatureCollection Congrats to all authors! @GrayCampLab
Yes, great thread! I think there's enormous potential in ML for biology. But to actually be useful, models need to be evaluated in scenarios that are practically relevant and against sensible baselines
Yes, great thread! I think there's enormous potential in ML for biology. But to actually be useful, models need to be evaluated in scenarios that are practically relevant and against sensible baselines
Still no new release of the IPhone mini- @Apple's greatest IPhone form factor :/
Friends, as the saying approximately goes: "Fortune favours the bald" 👴 👉 My proposal "HOLES: Higher-Order Learning of Essential Structures with Geometry and Topology" was successfully funded with a 1.5M € @ERC_Research Starting Grant! 👈 🤯🤯🤯 This will allow me to pursue…
🌟Scientists from #TeamIHB and @Roche #pRED have made an exciting discovery that could help to better predict a drug’s effect on the body.🌟 🔬Significant research now published in @Nature.🚀 🎉 Check it out spkl.io/6013f6wcD #RocheInnovation @IHB_Research
Fantastic paper that exemplifies the credo and mission of @IHB_Research: bold and creative young scientists as hands-on leads + projects combining biology, engineering, computation and drug development + extremely close collaboration between multiple research groups! Congrats!!
Fantastic paper that exemplifies the credo and mission of @IHB_Research: bold and creative young scientists as hands-on leads + projects combining biology, engineering, computation and drug development + extremely close collaboration between multiple research groups! Congrats!!
Intestinal Immuno-Organoids (IIOs): Striking differences between immune cells in the blood or resident in the intestine which are maintained in vitro! Implications for T-Cell Bispecific and other therapy? @Nature @EricTopol @Roche @IHB_Research nature.com/articles/s4158…
Very exciting to see our single-cell epigenomic atlas of human neural organoids published in @NatureNeuro !!! Fantastic work, Fides Zenk @EpiGN_Lab, Jonas Fleck @josch_f and the whole team !!! @ETH_BSSE @IHB_Research
Very exciting to see our single-cell epigenomic atlas of human neural organoids published in @NatureNeuro !!! Fantastic work, Fides Zenk @EpiGN_Lab, Jonas Fleck @josch_f and the whole team !!! @ETH_BSSE @IHB_Research
Great to see this out in print! Absolute dream collab with the brilliant Fides Zenk (@EpiGN_Lab) where we untangle #epigenetic regulation of neural #organoid development. If you're curious, here's the tweetorial 👇@GrayCampLab @TreutleinLab
Great to see this out in print! Absolute dream collab with the brilliant Fides Zenk (@EpiGN_Lab) where we untangle #epigenetic regulation of neural #organoid development. If you're curious, here's the tweetorial 👇@GrayCampLab @TreutleinLab
🚀Super happy that our latest research has finally been published in @NatureNeuro! We delve into the world of human neural development. Our findings shed light on the dynamic epigenetic changes that guide cell fate from pluripotency to fully differentiated neural cells.🧠🔬🧵
Single-cell profiling of H3K27ac, H3K27me3 and H3K4me3 histone modifications from progenitor to differentiated neural fates in human brain and retina #organoid models @TreutleinLab @GrayCampLab @JOSCHF @EpiGN_Lab @ethz nature.com/articles/s4159…
Single cell enthusiasts, get your flip-flops ready! Less than 24 hours until the registration to SCG2024 in Corinthia, Greece opens (April 3rd 3PM EU time) conferences.weizmann.ac.il/SCG2024/ Space is limited, don’t miss your spot!
🧬 Dive into #BrainDevelopment as PhD student! Join us for research in #MolecularBiology & #Epigenetics. 🧠✨ 🎓 Apply by April 15 to: epfl.ch/education/phd/… epfl.ch/education/phd/… epfl.ch/education/phd/… 👨🔬 Top facilities, science, great environment! #PhDPosition #EPFL 🚀
Thrilled to share my PhD work in the @TreutleinLab & @GrayCampLab! In this 🚨preprint🚨, we present an integrated perspective on how morphogens impact early human neural organoid development: biorxiv.org/content/10.110… Tweetorial landing in 3, 2, 1...

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