John Cuozzo @jwc54

SVP, Head of Drug Discovery, VantAI Massachusetts, USA Joined May 2011

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VantAI @vant_ai

6 months ago

Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)

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John Cuozzo @jwc54

11 months ago

Great to see this published - fantastic collaboration across multiple organizations pubs.acs.org/doi/10.1021/ac…

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Luca Naef @NaefLuca

a year ago

💥 Introducing PINDER & PLINDER With existing evals saturating without clear advances in real life downstream tasks, current progress in AI x Bio is primarily rate-limited by better datasets & evals. In two back-to-back preprints, we address this via fantastic academic-industry…

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David K. Yang @davidkmyang

a year ago

Induced proximity Glues & heterobifunctionals are exciting approaches that modulate proteins in new ways, e.g. degradation, phosphorylation, and stabilization, but the design rules remain inscrutable. VantAI is advancing AI e.g. PPI prediction to better optimize this drug class

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VantAI @vant_ai

a year ago

We made it no secret that we love @biotite_python! So much so that Biotite's Patrick Kunzmann has recently joined the team. This is the first of many releases where Patrick is contributing some of the tools he's built at @vant_ai back to Biotite.

Biotite @biotite_python

a year ago

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John Cuozzo @jwc54

a year ago

#aurora #NorthernLights Natick, MA

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John Cuozzo @jwc54

a year ago

#aurora #auroraborealis #NorthernLights

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John Cuozzo @jwc54

a year ago

linkedin.com/posts/vantai_a…

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Relay Therapeutics @Relay_Tx

2 years ago

Our first publication on RLY-2608, an investigational, first known isoform and mutant-selective allosteric PI3Kα inhibitor, is officially live in @CD_AACR. We extend our most sincere gratitude to our remarkable team of Relayers, collaborators, investigators and patients who are…

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bioRxiv @biorxivpreprint

2 years ago

Discovery of a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection followed by machine learning biorxiv.org/cgi/content/sh… #bioRxiv

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John Cuozzo @jwc54

3 years ago

Found several of these on a Cape Cod beach today. They look like leftover Thanksgiving carrots. Inside, they have yellow vein-like structures. Please identify this organism. #whatisthisthing

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John Cuozzo @jwc54

3 years ago

Amazing day yesterday at the Bicycles Battling Cancer ride organized by @AmericanCancer. Altogether we raised over $220,000 to support cancer patients. I broke my own personal distance record on my recumbent trike - 50 miles! Photo credit - @proteneer (Thank you!)

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Relay Therapeutics @Relay_Tx

3 years ago

⚠️ Drive with caution! ⚠️ 55 Relayers have taken the streets training for #BicyclesBattlingCancer. Cheer them on and…check your mirrors before turning!

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John Cuozzo @jwc54

3 years ago

A new documentary about cavernomas. Something I know quite a bit about from personal experience. youtu.be/yfJmjOye4OE

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John Cuozzo @jwc54

3 years ago

New from MIT news.mit.edu/2022/ai-model-…

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Relay Therapeutics @Relay_Tx

3 years ago

~195,000 people a year in the US are diagnosed with HR+/HER2- breast cancer. We are committed to reshaping their treatment options. In June, we announced the expansion of our breast cancer franchise: a selective CDK2 inhibitor, an ERα degrader & an additional pan mutant-PI3Kα.

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John Cuozzo @jwc54

4 years ago

Must see presentations at AACR!

Relay Therapeutics @Relay_Tx

4 years ago

Must see presentations at AACR!

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Relay Therapeutics @Relay_Tx

4 years ago

Hold on to your hard hats – we’re expanding! We’re doubling our footprint in Kendall Square. Twice the space. Twice the science. Twice the fun. #ProteinsOnTheMove

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Relay Therapeutics @Relay_Tx

4 years ago

🎥 From data milestones and an acquisition, to coming back together in person, 2021 was a year to remember. And we're just getting started! See you in 2022 – that’s a wrap! 🎬

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Relay Therapeutics @Relay_Tx

4 years ago

We work in a thriving industry making new medicines for patients, surrounded by incredible people who are committed to our mission. We are grateful we were able to bring our Relay Tx family together this month and wish everyone a happy Thanksgiving with your other families.