Kuldeep Kumar @kkumar_iitkgp
Postdoc, CHUSJ. Investigating the impact of genomic variants on human brain, and link to psychiatric risk. IIT-Engineer-ISRO-Neuro-Genetics. Data --- Pattern. kkumar-iitkgp.github.io Montreal Joined July 2011-
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"So transcription and decay don't seem to be tightly matched within a single cell at a given time after all. The balance between production + decay is only true in bulk." Excellent summary, and so many key takeaways.
"So transcription and decay don't seem to be tightly matched within a single cell at a given time after all. The balance between production + decay is only true in bulk." Excellent summary, and so many key takeaways.
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Kuldeep Kumar retweeted
We are proud to be one of the 13 projects funded by the NIH Autism Data Science Initiative. Our project: "Elucidating the Interplay of Genes and Environment in Autism Using Genomic and Exposure Data from Large Populations" 🧵nytimes.com/2025/09/26/hea…
Kuldeep Kumar retweeted
🚨 New preprint out! We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation. This reveals intensified assortment in recent generations. 🔗biorxiv.org/content/10.110…
Kuldeep Kumar retweeted
Exciting news! 🎉 Our Computational Neuroscience course has been awarded NIH BRAIN Initiative funding! Students will get hands-on experience w real BRAIN Initiative datasets! ➡️ Learn more: buff.ly/vfjjD3Y
"glia-neuron protein co-expression subnetwork is most strongly associated with AD".
"glia-neuron protein co-expression subnetwork is most strongly associated with AD".
Kuldeep Kumar retweeted
Here is our new preprint (medrxiv.org/cgi/content/sh…). We report heritability estimates for multiple traits using a within-family design in 500,000 sibling pairs of diverse ancestries! Fantastic collaboration with @23andMeResearch! Thanks to their participants and research team.
Kuldeep Kumar retweeted
Ever wish you could hit "undo" on disease? 🩺🔄 nature.com/articles/s4155… Most drug discovery asks: what does this perturbation do to cells? But we can also ask the reverse: which perturbations undo a disease signature and move cells back toward health? That's the idea behind…
Kuldeep Kumar retweeted
🔥🔥My new lab has a new Postdoc position, exploring how genetic factors and environmental factors (e.g., early life stress) influence brain development, child psychopathology, and neurodevelopmental disorders (e.g., autism) based on neuroimaging. Welcome uscjobs.sc.edu/postings/194578
Kuldeep Kumar retweeted
High costs motivate efforts to predict spatial transcriptomics from H&E images w/ deep learning. In our recent preprint, we show that noise, sparsity & resolution in ST data impact performance, highlighting the importance of training data quality: biorxiv.org/content/10.110… 🧵1/n
Kuldeep Kumar retweeted
📆 Mark your calendars! Neuromatch Academy 2026 courses are coming! 🧠 #ComputationalNeuroscience & #DeepLearning (6–24 July) 🌍 Computational Tools for #ClimateScience & #NeuroAI (13–24 July) ➡️ Applications open Feb 2026. Sign up for updates: buff.ly/i8h5t6f
Kuldeep Kumar retweeted
We are looking for a PhD student interested in studying the brain-immune axis, to understand the interaction between the brain and the immune system in ageing and psychiatric disorders. Large-scale brain imaging biobanks and in house collected datasets will be analysed.
Kuldeep Kumar retweeted
New Open dataset alert: 🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience! N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks! 🧵below
Kuldeep Kumar retweeted
Can we fuse adaptive and connectomic DBS? @neumann_wj & I say yes. Out in @NatRevNeurol: nature.com/articles/s4158… Thread here: shorturl.at/NtPMf
Kuldeep Kumar retweeted
🔥🔥Excited to announce that I am recruiting PhD students this fall. Our lab uses neuroimaging (MRI) and computational modeling to study the mechanisms of neurodevelopmental disorders, bridging genetic factor, brain circuitry, early life stress, and psychopathology. Please DM me
Nature | Single-cell transcriptomic and genomic changes in the ageing human brain Downregulation of short, highly expressed housekeeping genes with age, correlating with increased somatic mutation accumulation. Conversely, longer neuron-specific genes maintain their expression
Kuldeep Kumar retweeted
Most genetic reports label variants as ✅ “pathogenic” or ❌ “benign.” But what patients really want to know is: what are my chances of getting the disease? 🚨 In our new Science study, we used AI + 1.3M patient records to better answer that…
Kuldeep Kumar retweeted
Two flagship papers from the International Brain Laboratory, now out in @Nature: 🧠 Brain-wide map of neural activity during complex behaviour → doi.org/10.1038/s41586… 🧠 Brain-wide representations of prior information in mouse decision-making → doi.org/10.1038/s41586… +
Kuldeep Kumar retweeted
super cool, this used to take forever back when we were making AI simulation games like Republic.
super cool, this used to take forever back when we were making AI simulation games like Republic.
Kuldeep Kumar retweeted
Check out our new preprint on Streamline Density Normalization (SDNorm)! SDNorm can reduce bundle variability, improve reliability of along-tract microstructure, and provide metrics for automated bundle QC. 📎Paper: biorxiv.org/content/10.110… 📎Code: github.com/wendyfyx/SDNorm
Kuldeep Kumar retweeted
I was fortunate to work with my role model @foxmdphd . Thank you for the quality time you created for us, for the big encouragements, for the seemingly small yet powerful daily encouragements, for your consistency, for supporting us in challenging times, your genuine respect for…
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