Mitesh Joshi @m_joshi1
Definite optimist - bred by effort. Software engineer - making an effort to put quality in quantity. Staying upwind. recovering from knowledge porn. linkedin.com/in/mitesh-josh… Bengaluru, India Joined December 2010-
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"S3 is cheaper than EBS". This is the top reason why people want using S3 as a persistent storage for databases such as VictoriaMetrics and VictoriaLogs. They are correct - S3 costs $23/TB/month, while EBS gp3 costs $80/TB/month (but there is st1 at $45/TB/month and sc1 at…
🚨 Big news in ML for biotech 🚨 Today, we're launching the Antibody Developability Prediction Competition with @Ginkgo + @huggingface! 💧 Hydrophobicity 🎯 Polyreactivity 🧲 Self-association 🔥 Thermostability 🧪 Titer 🏆 Up to $60k in prizes 📅 Submit by Nov 1, 2025
Excited to share that the Arce Lab is launching today at @arcinstitute ! We will explore the mechanisms controlling immune cell function using genomics and biochemistry in an effort to understand immune-mediated diseases. arcinstitute.org/labs/arcelab
The good news? We're getting smarter at building and thinking about systems that avoid coordination until necessary. You can think of NoSQL, MapReduce, Java's parallelsStream, Rust's Rayon, and even CQRS as innovations in that direction. Some principled, some not so principled.
I'll look at Ray tomorrow live youtube.com/live/IK1z15R5W…
A transaction is not durable if it survives application crash but not OS crash. A committed transaction is either durable or not!
Pro tip: If you solve the clock skew problem, most problems in distributed systems become attainable with common sense methods. I’m glad that someone decided to go against the laws of physics and partially solved this problem.
Interesting blog - observation on infra. as code - resource schema, resource catalogue generation, and convergence engine blog.nelhage.com/post/declarati…
last month I gave a talk at @StanfordMed on the future of healthcare. spoiler: in the next 10 years it's going to look dramatically different. why? – the rise of large language models – ubiquity of healthcare APIs – the doubling of healthcare data every year – a consumer…
If you don't know what you want, every distraction will look like an opportunity.
You get in relationships to LEARN how to love each other, you're not suppose to automatically know. People assume this and are too quick to break up.
You get in relationships to LEARN how to love each other, you're not suppose to automatically know. People assume this and are too quick to break up.
Don’t chase closure through someone else. If they could provide you the closure you need, they wouldn’t have put you through what they did.
Don’t chase closure through someone else. If they could provide you the closure you need, they wouldn’t have put you through what they did.
Generative AI is the new lab assistant in longevity research. What once would take 150 years can be done in a month and for one billionth the cost
on my 26th birthday, i wrote I Took A Pill in Ibiza...11 years ago. The song became popular several years after i wrote it. This year I celebrated my 37th birthday. I feel proud to look at the song lyrics and know that NONE of them are true anymore. I've grown into a completely…
Sometimes you really do just need a better data structure. Subscription worker CPU and latency on one of the highest subscription-count @convex_dev projects, before and after switching to a treap-based data structure:
Asked the Head of AI at a Fortune 500 how he decides buy vs build, and his framework feels widely applicable: “we buy what accelerates us, and build what differentiates us”
i don’t think you understand you train a small model on scikit-learn it gets 80% accuracy you fine-tune a huggingface transformer it gets 90% accuracy you build a custom data pipeline it gets 93% accuracy you ensemble three models with voting it gets 95% accuracy you…
“He only hangs out with models now” means a very different thing in SF
New blog post, with some career advice: brooker.co.za/blog/2025/06/2…
Delayed gratification is good. But how much is too much?

Sourik @Sourik24
285 Followers 2K Following Making GPUs and CPUs go Brrrrr @ https://t.co/CXXbtt3IPU , GPU tinkerer, Compiler Fanatic, Code Slinger, Harry Potter and Star Trek Nerd, Full-Time LEGO Connoisseur
NancyWylde @z97xV1hKMzCisr
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Erjouodar @Erjouodar7533
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Farhad Afshar, MD @FarhadAfsharMD
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Ydroojaw @Ydroojaw7132
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Emily Grace @lank2525
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Obocea @Obocea4846
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Pathway @PathwayMedical
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Thlears @ThlearskD7uU
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Audrokrau @Audrokrau75548
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Alejandra @alejandra_beame
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Davide Pisu @mtbmeds
2K Followers 2K Following | Host-pathogen interactions w/ M. tuberculosis 🦠 | Macrophages 🔬 | Infectious diseases 🧫 | Soccer ⚽ & F1 🏎️ enthusiast!
Lois @mitchell_lois37
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Diana @mcnamee_diana60
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Roman Agabekov @agabekovroman
4K Followers 3K Following Building in public Autopilot for databases 🕹️🔄 Founder @releemhq (https://t.co/Ny4n5ske07) - Easy-to-use Database Performance Management tool 🛠️
Linqing Liu @likicode
879 Followers 459 Following Applied AI @Databricks | PhD @ucl_nlp | ex-Research Scientist intern @GoogleDeepMind @SFResearch
authzed @authzed
2K Followers 1K Following Creators of SpiceDB: https://t.co/oSDTIhg5xi Read how ChatGPT uses AuthZed for authorization: https://t.co/anUr0CQZuL
Fabrizio Montesi ⬣ ... @famontesi
662 Followers 500 Following Marchigiano 🇮🇹 in 🇩🇰 | Author of #ChoreographicProgramming and 'Introduction to Choreographies' | Maintainer @jolielang | Pres. @c_microservices
Jon Morehouse @nuonjon
911 Followers 3K Following Bring your own cloud, for everyone. - https://t.co/P44GwYDwlk
Jaikumar Ganesh @jaikumarharikoa
210 Followers 642 Following Head of Engineering at @anyscalecompute, ex Uber, ex Android@Google
ry @rywalker
9K Followers 5K Following ceo @tembo • prev founder/ceo @astronomerio (yes, that astronomer) • I follow back all startup people who post, and unfollow unfollowers
Jay Jackson @jaybjackson
1K Followers 5K Following I compete and follow Triathlon. I love running trails and MTB’s. Lawyer by day. Litigator! World Triathlon Technical Official for USA Triathlon
François Massot 🦀 @FrancoisMassot
2K Followers 2K Following Co-founder @Quickwit_inc, OSS cloud-native search engine for Logs and Traces #rust #maths #chess @[email protected]
Mayank Sharma @mayyyaank
16 Followers 246 Following
jai @jai_chopra
379 Followers 369 Following Building at @Uber. Previously @lancedb @Cruise. From 🇦🇺 now in 🇺🇸
Philip Tannor @PhilipTannor
6K Followers 5K Following CEO at Deepchecks | Moderator at https://t.co/eIctpd8n3A | Forbes 30 Under 30 | Open Source Validation of AI & LLMs https://t.co/e8ivMRLuEp
Burkay Gur @burkaygur
6K Followers 2K Following Co-founder at @fal. Previously @coinbase, @MIT_CSAIL
Victor Castell @vcastellm
1K Followers 2K Following Blockchain eng at @0xPolygonLabs, @AKASHAworldBCN Collab, https://t.co/QAN5GwC6cr author, decentralized systems and crypto. Also synths and Filipino Martial Arts
hubert dulay @hkdulay
803 Followers 2K Following “Streaming Data Mesh” & “Streaming Databases” OReilly Author @startreedata ex-@confluentinc ex-@cloudera #datamesh #clusterheadaches 🇵🇭🎸🥁🎹🤘
Synnada @synnadahq
227 Followers 135 Following Rethinking AI systems from first principles. Simpler rules, sharper tools. Built for those who build with AI.
Florian Leibert 🎢 @flo
12K Followers 4K Following GP @468capital. Founder @mesosphere, ex @twitter & @airbnb. prototype not meant for mass production. the 🇺🇸 dream is real.
Dr. Todd Ewing PhD @EwingT_PhD
4K Followers 2K Following Researcher / Aging / Fitness / Longevity / @ewingt-phd.bsky.social / Read my book BIOLOGICAL YOUTH: How to naturally promote youthfulness & prevent frailty
Joran Dirk Greef @jorandirkgreef
8K Followers 2K Following Creator, Founder and CEO of @TigerBeetleDB — the financial transactions database designed to power the next 30 years of transaction processing.
TigerBeetle @TigerBeetleDB
8K Followers 1K Following The financial transactions database designed to power the next 30 years of transaction processing.
GarrenSmith @GarrenSmith
563 Followers 549 Following @tigrisdata founding engineer. Apache @CouchDB PMC Go, Rust, distributed systems and Databases. Avid climber
James Pearce @jamespearce
9K Followers 4K Following TinyBase and other local-first & sync goodies. Previously: Eng Director at Meta, data infra, dev tools, open source, & platforms. Now: hacker & sailor.
Ankush Desai @ankushpd
2K Followers 777 Following Principal Scientist @AWS. Formal methods, systematic testing, fuzzing applied to distributed systems. Creator of P : https://t.co/Xnbk9a6xUw
Bart Veenman @bveenman
2K Followers 3K Following Sr Manager AI @KPMG_NL Data & Analytics | AI | GenAI | Predictive AI | Data | Strategy | Responsible AI | Digital Engagement
Mim @mim_djo
11K Followers 3K Following #MicrosofFabric user advocate, interests in Small Data & Self Service #Microsoftemployee since Dec 2023 , but my tweets are my own
Rahul Jain @rahulj51
3K Followers 2K Following Principal Software Engineer at @justbobsledit. Formerly led Data and Engineering at @thebeatapp , @omioglobal , @thoughtworks .
Srinikhil Naravamakul... @manchicoffee
353 Followers 3K Following Builds, breaks things for @AzureCosmosDB.
Jyotinder Singh @Jyotinder_Singh
4K Followers 1K Following Keras and Core ML @Google | Built @thedicedb | I travel and take photos 📸
Stas Bekman @StasBekman
9K Followers 286 Following Toolmaker. Software creator, optimizer and harmonizer. Makes ML systems work and fly @ Snowflake.
Langbase @LangbaseInc
3K Followers 1 Following ⌘ Langbase — Serverless AI Developers Cloud for building AI products like AI agents with memory (RAG). Billion tokens/day scale. Creators of https://t.co/ftOtI3QZrI
Amir Yazdan @ayazdanb
2K Followers 964 Following Research Scientist at Google DeepMind. TPU Co-design, Machine Learning and Accelerator Design. #ComputerArchitecture #ML4Code
Raul Junco @RaulJuncoV
31K Followers 500 Following I simplify System Design, and System Design will make you a better Software Engineer. System Design • Databases • Algorithms • AI Enthusiast
Hao AI Lab @haoailab
4K Followers 343 Following Hao AI Lab at UCSD. Our mission is to democratize large machine learning models, algorithms, and their underlying systems.
Zeeshan Patel @zeeshanp_
8K Followers 687 Following @xAI | prev research @nvidia @apple @berkeley_ai | views my own
Kan Wu @flyflyf04862062
681 Followers 405 Following Inference @xai, PhD @WisconsinCS. Prev: Google, USTC. Machine Learning Systems, Distributed Systems. Tweets are my own.
Sourik @Sourik24
285 Followers 2K Following Making GPUs and CPUs go Brrrrr @ https://t.co/CXXbtt3IPU , GPU tinkerer, Compiler Fanatic, Code Slinger, Harry Potter and Star Trek Nerd, Full-Time LEGO Connoisseur
Prafulla Dhariwal @prafdhar
43K Followers 516 Following Technical fellow @OpenAI. Co-creator of GPT-4o, GPT-3, DALL-E 2, Jukebox, Glow, PPO. Previously @MIT '17
EXO Labs @exolabs
37K Followers 2 Following AI on any device. 12 Days of EXO: https://t.co/VMrJ6Vi4h3 We're hiring: https://t.co/BzEO8ZCvBV
Microsoft AI @MicrosoftAI
2K Followers 6 Following We build responsible AI to empower people | https://t.co/A80GqUp4Kb
biraj (બિરજ) ... @biraj21_
4K Followers 276 Following founding engineer @OutspeedAI, building realtime voice ai infra. resident @lossfunk. wannabe solo founder. in my cringe era.
Sushant @sushantpandey_
1K Followers 3K Following Founder @pravapayments -Payments API for AI Agents | Econ-BHU'22 | art @artstreax
Shubham Kukreti @ShubhamKukretii
1K Followers 950 Following @PravaPayments - Payments API for AI Agent | resident @lossfunk batch 6
Mave Health @mavehealth
239 Followers 17 Following The world's first antidote to modern lifestyle—a neurotech-powered membership designed to help you improve your mental wellbeing. 👊 Join waitlist 👇
Collin Brown 💯 @CollinBrown85
1K Followers 1K Following MS Psychology. CPT, NBC-HWC. Nouthetic Performance Coach for Men. Trinity Fitness Phoenix Facility Director.
The Whole Truth Foods @wholetruthfood
6K Followers 34 Following Rebuilding the 🌎’s trust in its food. Subscribe to Truth Be Told, our newsletter on food & fitness - https://t.co/oVPCfkKTPe
anshuman @athleticKoder
15K Followers 823 Following machine learning engineer; prev: ai consultant @google, mle @ https://t.co/7tFP7MHyLH, gsoc @tensorflow
Ramp @tryramp
27K Followers 822 Following The all-in-one financial operations platform that saves businesses time and money. Trusted by 45,000+ teams.
Yichao 'Peak' Ji @peakji
25K Followers 170 Following Co-founder & Chief Scientist of Manus @ManusAI_HQ
Psychodoctor @Psychodoctor06
25K Followers 726 Following Psychiatrist, Therapist. I help people to stay mentally healthy. DM for online consultation
PepTracker App @PepTracker
26 Followers 6 Following Track, schedule, and calculate your peptide doses with confidence. Download PepTracker for free ⬇️
Lovepreet Singh 🌱 @SinghDevHub
13K Followers 300 Following 📍 backend & ml @CRED_club • distributed systems + applied mathematics • interested in solving problems in any xyz stack
maharshi @mrsiipa
41K Followers 863 Following ml perf @fal - learning deeply about life one gradient step at a time - personal blog: https://t.co/TYdFfUBImf
mem0 @mem0ai
12K Followers 13 Following The Memory Layer for your AI apps. Backed by @ycombinator. Open source: https://t.co/HqLHhUMmAf
Amanda Bertsch @abertsch72
2K Followers 872 Following PhD student @LTIatCMU / @SCSatCMU, researching long context + decoding | she/her | also @ abertsch on bsky or https://t.co/L4HBUh0R9f or by email (https://t.co/bsHqwIMFPL)
Graham Neubig @gneubig
40K Followers 710 Following Associate professor @LTIatCMU. Co-founder/chief scientist @allhands_ai. I mostly work on modeling language.
Reginald Long @reggylong
591 Followers 288 Following co-founder of Rhythm - curing all sleep diseases one at a time.
Eric Zelikman @ericzelikman
21K Followers 2K Following building for humans // was lgtm-ing @xAI, phd-ing @stanford
Neil Stone @DrNeilStone
111K Followers 18K Following Infectious Diseases doctor. Clinician-scientist.Officially the 1st person to use word #Covid. Strictly my personal views only. No DMs for medical advice.
Prime Intellect @PrimeIntellect
48K Followers 28 Following find compute. train models. contribute to open superintelligence. https://t.co/ZRZOsRRbwr
Kyle Kranen @KranenKyle
199 Followers 29 Following Hobby Data Scientist 📈 Professional Deep Learning Engineer at Nvidia 💻 Cal Alum 🧸
Alexander Nevedovsky @ednevsky
1K Followers 4K Following built @nocap_so, a viral agent backed by @ycombinator; repeat AI founder with an exit (wanna to farfetch); ex-palta (200M users); nc/acc 🚀
Joy Arulraj @joy_arulraj
2K Followers 260 Following Associate Professor @GeorgiaTech. Data systems and AI. Member of the @CMUDB mafia.