Martin Pera @martinperaJAX
Professor @jacksonlab, stem cell biologist, Associate Editor @ISSCR Stem Cell Reports jax.org/research-and-f… Bar Harbor, ME Joined July 2019-
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Brachyury expression levels predict lineage potential and axis-forming ability of in vitro derived neuromesodermal progenitors biorxiv.org/content/10.110…
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Single-cell nascent transcription reveals sparse genome usage and plasticity: Cell cell.com/cell/fulltext/…
Stable Maintenance of Two-Cell-Like Cells from Embryonic Stem Cells Reveals Chromatin and Super Enhancer Regulation of MERVL Elements biorxiv.org/content/10.110…
Dual-patterned pluripotent stem cells self-organize into a human embryo model with extended anterior-posterior patterning biorxiv.org/content/10.110…
Drivers and implications of lineage-specific cancer-related mutations in human pluripotent and adult stem cells: Stem Cell Reports cell.com/stem-cell-repo…
Signaling reprogramming via Stat3 activation unravels high-fidelity human post-implantation embryo modeling: Cell Stem Cell cell.com/cell-stem-cell…
Saitou, M., Nagano, M. & Mizuta, K. Mechanisms of human germ cell development. Nat Rev Mol Cell Biol (2025). doi.org/10.1038/s41580…
Human adult hippocampal neurogenesis is shaped by neuropsychiatric disorders, demographics, and lifestyle-related factors: Cell Stem Cell cell.com/cell-stem-cell…
Martin Pera retweeted
Mouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
A phenotypic brain organoid atlas for neurodevelopmental disorders biorxiv.org/content/10.110…
Emerging principles and models of human primordial germ cell development journals.biologists.com/dev/article/15…
Frozen potential: embryo research at the crossroads of ethics, regulation and scientific opportunity journals.biologists.com/dev/article/15…
Low nucleus to cytoplasmic ratio compromises cytokinesis, genome stability and development in haploid embryonic cells biorxiv.org/content/10.110…
Sekulovski, N., Carleton, A.E., Rengarajan, A. et al. CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates. Genome Biol 26, 263 (2025). doi.org/10.1186/s13059…
Lindenhofer, D., Bauman, J.R., Hawkins, J.A. et al. Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing. Nat Methods (2025). doi.org/10.1038/s41592…
A mouse organoid platform for modeling cerebral cortex development and... sciencedirect.com/science/articl…
Martin Pera retweeted
Congratulations to Yale Genetics faculty Dr. Berna Sozen @BernaSozen_ and Dr. Steven Reilly @ReillyLikesIt, who have been named 2025 Pew Biomedical Scholars! 🎊🧬🔬medicine.yale.edu/news-article/y… #PewBiomedicalScholars #Genetics
Pretemer, Y., Gao, Y., Kanai, K. et al. An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification. Nat Commun 16, 7680 (2025). doi.org/10.1038/s41467…
Transient gene melting governs the timing of oligodendrocyte maturation: Cell cell.com/cell/fulltext/…
Contractile function maintains cardiomyocyte differentiation and inhibits cell cycle activity biorxiv.org/content/10.110…
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