Sumedh Neni @sumedhsunks
NYC Joined August 2011-
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Sumedh Neni retweeted
$TECX presents data for their phase 1B trial. Not much new, but something that caught my eye. Supports my thesis Relaxin ST Vasodilation gives way to longer term antifibrotic effects. TAPSE/SPAP plateaus and declines quickly because day 1 vasodilation leads to fast improvement. (this is a ratio measuring both function and resistance). RVFAC continues to improve slowly because anti fibrotic effects are longer term. Think this could be why CpC PH patients are ideal because they have vascular remodeling in Pulm Vasculature.
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