Abdullah @0x_abdullah

😱😱 “…there are now 120+ "in vivo CAR-T" companies in China.” 🇨🇳

David Li @davidycli

2 days ago

😱😱 “…there are now 120+ "in vivo CAR-T" companies in China.” 🇨🇳

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I finished my estimate on required compute to make an atomic-resolution virtual cell: 10^38 FLOPs to simulate a human cell for 1 day. We should be able to do this simulation in 2074 using 200 TW of power. 1/3

I became Senior VP at a multi-million dollar company at age 26. My salary was $600k. This was in 2018. How did I do it? It wasn’t hustle culture. No 5:30am wakeups, cold showers, or productivity hacks. What got me there was a relentless focus on impact. Every project I…

I think one of the largest issues in my life currently is that I'm simply never bored. Boredom creates space for doing, a space to develop discipline. It's a vacuum begging to be filled but it's far to easy these days to fill when the world is at my fingertips. I can hop on here…

For now, since I don’t want to have us all buy embryos on some social media marketplace through some AR glasses, I urge us to start a counterculture of love. Biology’s greatest “feature” has never been an eye color, fur texture, or voice tone. The most beautiful “feature” of…

The internet has no rules. Everything you think is "normal" online was made up. The stock market wasn’t supposed to be memes. Currency wasn’t supposed to be jokes. Attention wasn’t supposed to be money. But now it is. Why? Because enough people agreed it should be. Tokens…

Can AI cure disease & make science faster? @pdhsu @JorgeCondeBio and @eriktorenberg discuss (00:45) The Moonshot: Virtual Cells and Human Biology (02:58) Interdisciplinary Collaboration at Arc Institute (05:11) The Role of AI in Biology (10:18) Understanding Virtual Cells…

It is incredible that GLP1s work for reducing cravings with evidence in alcohol use disorder, opioid use disorder, and cannabis use disorder. A little peptide that comes from the proglucagon gene primarily made by pancreatic and gut cells (and to a lesser extent in the brain)…

Jake Wintermute 🧬/acc @SynBio1

3 weeks ago

It is incredible that GLP1s work for reducing cravings with evidence in alcohol use disorder, opioid use disorder, and cannabis use disorder. A little peptide that comes from the proglucagon gene primarily made by pancreatic and gut cells (and to a lesser extent in the brain)… https://t.co/YTGRSatRD4

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Check out our new perspective "Illuminating the universe of enzyme catalysis in the era of artificial intelligence" now out in @CellSystemsCP ! We discuss a vision and path forward for genetically encoding almost all chemistry, powered by new AI tools: authors.elsevier.com/c/1lg4h8YyDfuZ…

One of the most epic framings of human genetics that lives rent-free in my head: "The human population, through explosive growth, has performed a comprehensive saturation mutagenesis experiment on itself. It is now the case that any single base substitution that is compatible…

Our inaugural BioAgent @Aubrai_ has awakened. Prompt it to birth novel hypotheses, alchemized from @aubreydegrey's intellect. Years of private lab notes, emails, a knowledge graph of +4k papers, fine-tuning on @PrimeIntellect compute, fused with the best LLMs Every hypothesis is…

The Aitchison College Rocketry Team has tested its Delta 5 Engine, generating 40 KGs of thrust for 4 seconds at mach 2.5 speed. They claim its the most powerful rocket engine developed by a non-military organization in Pakistan. I think this is the sort of healthy innovation…

I spent 1.5 years at MIT designing a new undergraduate program in Genetic Engineering. One of our theses in designing that program (which I’ll share more about soon; I'm writing a long essay about it) was that undergraduate students could be trained to be excellent genetic…

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Human 1.0 (currently we’re here): cavemen stage Human 2.0: indefinite lifespan and aging solved. (Stay young and alive as long as you want) Human 3.0: genetically engineered. evolve to human sub-species Human 4.0: pure energy, light, and quantum information. Live in their own…

Cell-free protein synthesis systems, optimized at Ginkgo and now available to you! Ginkgo has been using cell-fee protein synthesis systems in house for years, and we’re now making our E. coli system available to outside users! We’ve optimized it for: • High production from…

sending bitcoin over bluetooth between bitchat android and iphone. both have a native cashu ecash wallet built in. the ecash travels directly from phone to phone. the sender needs no internet. like instant and untraceable digital cash. work in progress. it's going to be insane.

Every law needs a sunset thenews.com.pk/print/1329090-… A good suggestion. Pakistan needs to revamp, repeal, and rewrite ALL colonial-era laws made before August 1947. Don't we have good lawyers who can rewrite the PAKISTAN PENAL CODE 1860? But Elite rulers are reluctant to do it!

Jellyfish reverse their aging when stressed lobsters produce telomerase forever trees live for thousands of years death isn't universal in nature it's just common in mammals let's make death optional

DUHS develops Pakistan’s first indigenous anti-rabies vaccine in lab-scale breakthrough profit.pakistantoday.com.pk/2025/07/15/duh… via @Profitpk Excellent!! "This marks the first time a human vaccine in Pakistan has been developed from a completely indigenous biomolecule," Govt must fund RESEARCH.

So you want to organize a "pop up" village? Sharing some operational learnings from organizing, supporting, and participating in many Zuzalu inspired pop up villages in the last 2 years: 2 initial decisions to make: - urban or rural / isolated - top-down accommodation…