Andre Leitao @Andre_Leitao87
Postdoctoral Researcher at University of California, San Diego, CA San Diego, CA Joined July 2013-
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"O Governo vai investir 121 milhões de euros em microelectrónica até 2027 (com outros 207 milhões de euros de fundos europeus na calha)". Qd até 2029 haverá apenas 105 milhões por ano para todos os centros de investigação em PT, alguém perguntou porquê?
"O Governo vai investir 121 milhões de euros em microelectrónica até 2027 (com outros 207 milhões de euros de fundos europeus na calha)". Qd até 2029 haverá apenas 105 milhões por ano para todos os centros de investigação em PT, alguém perguntou porquê?
"This transition reflects our broader commitment to open science" Wait. What?!?!?
"This transition reflects our broader commitment to open science" Wait. What?!?!?
New #SingleMolecule fluorescence method to track interactions with α-SYN & other proteins in #LewyBody inclusions – hallmarks of #Parkinsons & other neurodegenerative disorders. Research from InteracTeam @EMBLAustralia @UNSWMedicine now out in @CommsBio. disq.us/t/41dci0i
Do you want to know how your protein of interest ends up in Lewy Bodies in #Parkinsons? We present the interactome of monomers, oligomers and fibrils of alpha-synuclein. nature.com/articles/s4200…
Leitão et al. present a method to measure interactions of monomeric, oligomeric, and fibrillar forms of α-syn with 65 proteins that were previously shown to be components of Lewy bodies. @UNSW; @SingMolSci, @EMBLAustralia, @Andre_Leitao87 nature.com/articles/s4200…
Often forgotten that #Parkinsons-associated Lewy bodies contain over 70 proteins; Now research from @Andre_Leitao87 & @EMBLAustralia colleagues explores the selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein nature.com/articles/s4200…
congratulations to @PappulabWashU and @TanjaMittag! looking forward to the forthcoming #quantitativeandrigorous research from your groups
congratulations to @PappulabWashU and @TanjaMittag! looking forward to the forthcoming #quantitativeandrigorous research from your groups
Nature.com: Tips from neuroscience to keep you focused on hard tasks. nature.com/articles/d4158…
Out today. pnas.org/content/118/10…
Gitler lab paper alert🚨: @lumberjacob91 performed single nucleus RNAseq on motor neurons from mouse spinal cord. Tons of previously unrecognized diversity that opens up possibilities for functional studies and selective vulnerability in ALS. Check it out: spinalcordatlas.org
This review / perspective looks timely, relevant, and interesting sciencedirect.com/science/articl…
Anna Bock and Anastasia Murthy led this effort to show that N-terminal acetylation has a very slight but reproducible impact on in vitro LLPS of FUS LC but does slow in vitro conversion to an aggregated state in some conditions. Thanks Jeetain Mittal and Frank Shewmaker too!
Anna Bock and Anastasia Murthy led this effort to show that N-terminal acetylation has a very slight but reproducible impact on in vitro LLPS of FUS LC but does slow in vitro conversion to an aggregated state in some conditions. Thanks Jeetain Mittal and Frank Shewmaker too!
Our paper on the role of Rab19 in cilia formation finally has been published in Developmental Cell. Great job Cayla @caylajewett sciencedirect.com/science/articl…
If you are interested in Multiphasic Condensates and Liquid-Liquid Phase Separation of Multicomponent Mixtures, please check out our recent paper below!
If you are interested in Multiphasic Condensates and Liquid-Liquid Phase Separation of Multicomponent Mixtures, please check out our recent paper below!
Just out! If you liked our recent study in @PNASNews on proteostasis decline in human senescence - learn more on proteostasis decline with age in humans, in light of >decade of knowledge in worms in our recent review: doi.org/10.1016/j.yexc…
#EMBOcellpolarity is on! Catch up on all the latest research at the interface of cell polarity and membrane dynamics - May 16-21, 2021. More at bit.ly/39f2rJT #cellpolarity #membranedynamics #cellbiology @EMBOevents @Spang_Lab
Kenneth "Matt" Scaglione, Ph.D., Assistant Professor in the Department of Molecular Genetics and Microbiology at Duke University is our Seminar Series Speaker, this Thursday, February 4, at 3 pm.
across disorders. Link: cell.com/cell-reports/f…
Similar to transcriptomic imputation, here the authors used proteomic imputation (predicting protein levels using cis-SNPs) to identify brain proteins differentially expressed in Alzheimer's disease. Nice! nature.com/articles/s4158…
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645 Followers 618 Following Lecturer at Imperial College London; UK-DRI Group Leader working on circadian rhythms in health and dementia; chronobiologist. Opinions are my ownSabina Leonelli @SabinaLeonelli
9K Followers 6K Following empirical philosopher of science | director Egenis | editor @HPLSjournal | https://t.co/YaT1TXPyti @StudiesOpen | https://t.co/dEp4PYMYo3Molecular Machines Gr.. @Mol_Machines
237 Followers 244 Following We develop fluorescence imaging approaches to visualise the dynamics of self-assembly processes at the single-molecule level. Tweets by group members.Sara Leitão @sdgl10868
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39K Followers 627 Following The HBP ran from 2013 to 2023, as a EU Flagship Project. This account is no longer active, follow @EBRAINS_eu for news from the EBRAINS Research Infrastructure.EBRAINS @EBRAINS_eu
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551 Followers 58 Following A national network of MND centres that work together to understand how #MND happens, what treatment works, and test possible treatments in clinical trials.Fala-me Neuro @FalameNeuro
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3K Followers 599 Following L'Institut #PasteurLille est une #fondation privée reconnue d'utilité publique dans le domaine de la #santé et de la #recherche #médicale et #scientifiqueFondation Recherche A.. @Alzh_Fondation
3K Followers 573 Following #fondation reconnue d'utilité publique finance la recherche d’excellence sur la maladie d’#Alzheimer, Pitié-Salpêtrière, Paris. [email protected]@AdrianoAguzzi We are waiting for you to come back to educate us with your awesome new discoveries, including those from your large CRISPR screening efforts. Science needs you!
Peptides possess the power to spark propagation of tau fibrils, or to dismantle fibrils entirely. Two studies point to therapeutic strategies for tauopathies. @ucsantabarbara @UCLA ow.ly/fGY750RkjcX
After my first visit 30y ago 😱 as PhD student, it was a pleasure returning to @SapienzaRoma 🇮🇹 Dpt Scienze Biochimiche Rossi Fanelli for a seminar on protein self assembly and chaperones and meet so many old friends! Thanks for having me! phd.uniroma1.it/web/chaperones…
Stay at @UChicago comes to an end! Many thanks to @KrishnanYamuna and lab for hosting! Thanks to all the other fantastic people I have had interactions with! Being on the path of eclipse was a bonus, coming from down under!
I am in La Jolla for the next 4 days, going for walks with my daughter and talking at Scripps this Friday. If you want to discuss arrayed CRISPR screens and/or get me some coffee, I am game.
Paper out @jbiolchem: collaborating with the Landrieu & @LucBuee labs @univ_lille we contributed to study antibodies targeting in Tau. The first publication from our bilateral 🇵🇹🇫🇷 project TANDEM @fct_pt @CampusFrance🧠@BioISI @cienciasulisboa ➡️doi.org/10.1016/j.jbc.…
(2/2) This project has as partners: @HelmholtzMunich, @Fraunhofer, @SingleTechn, @HovioneGroup and @SPI_SOC. Read more about this news 👇 cnc.uc.pt/en/tres-milhoe… #CNCResearch #InnovativeTherapies #Neuroscience #Regeneration
(1/2) A European research consortium funded with 3M€, led by the @UnivdeCoimbra and #CNCResearcher Lino Ferreira, will develop an innovative technology that could boost the regeneration of neurons in diseases that currently have limited therapeutic options.
Today was the kick-start of the NeuroCurios@s adventure with school kids from Escola Básica de Cantanhede, with our ERA Chair holder @CrisMarquezVega introducing the misteries of the brain. #BrainAwarenessWeek
It's now time for our Shift 2⃣ posters on #ADPD2024: ☑️ Chaperone regulation of Tau LLPS (#0444) ☑️Aggregation-inhibiting nanobodies (#0045) Come and meet talented Guilherme @GuilhermeGilMo1 and Margarida during poster sessions on day 3⃣! @adpdnet
Countdown to #ADPD2024 🧠Come and meet us to explore our research on chaperones and protein aggregation in posters and talk📨 DM to set a meeting for discussions and potential collaborations. See you there! 🇵🇹
#ADPD2024 📢 I invite everyone to pass by my poster #444 in order to get insights to #Tau #PhaseSeparation #LLPS and #ProteinAggregation modulation by #S100B #chaperone 🤩 See you soon! 🧪👨🔬🔬
It's now time for our Shift 2⃣ posters on #ADPD2024: ☑️ Chaperone regulation of Tau LLPS (#0444) ☑️Aggregation-inhibiting nanobodies (#0045) Come and meet talented Guilherme @GuilhermeGilMo1 and Margarida during poster sessions on day 3⃣! @adpdnet
Countdown to #ADPD2024 🧠Come and meet us to explore our research on chaperones and protein aggregation in posters and talk📨 DM to set a meeting for discussions and potential collaborations. See you there! 🇵🇹
We’re just TWO days away from the leading event in neurodegenerative disorders - #ADPD2024! 📅This is the time to explore the scientific program and mark your must-attend sessions for an enriching experience. Plan your schedule in advance: bit.ly/42No1PZ
For two years, Ukraine has shown not only immense strength and courage but also intellect and talent. Our research, education or culture programmes have been part of EU support to the country defending itself against the Russian aggression and to people fleeing the war 👇 1/4
Knight Initiative director Tony Wyss-Coray (@wysscoray) and others are leading the development of a test measuring organ-specific proteins in the blood as a simple and sensible way to estimate biological age. shha.re/byRpi
Exciting times for the lab as we go multicellular @EMBLAustralia. Image taken on an Airy beam light sheet. Airy beams have been extensively explored for microscopy by @OpticManip. This custom microscope was implemented with @M2Lasers.
We are hiring! CNC-UC is looking for 1 Science Communication and Marketing Officer for the GeneT project. Deadline: February 29, 2024 Learn more and apply at 👉 euraxess.ec.europa.eu/jobs/188350 #CNCOpportunities #CNCJobs
Out today 📣Secondary Modification of S100B Influences Anti #Amyloid-β Aggregation Activity and #Alzheimers Disease Pathology🧠a 🇵🇹🇮🇪 collaborative effort👏 congrats to the team! @BioISI @iMedULisboa @BernalNews @UL @cienciasulisboa @IJMS_MDPI mdpi.com/1422-0067/25/3…
Breaking any negative pattern or starting over in life, always starts with believing in yourself and that you can do it. And that you deserve better. 💫
Watching that cover slide from the front row, can't wait for what @Pawel_Burkhardt has in store! Exploring the nervous system of distant organisms is fascinating science.org/doi/10.1126/sc…
Excited & thankful to give a plenary lecture on the "Evolutionary origin of neurons" at the Norwegian Bioscience Society Meeting #NBS2024. Bonus point: sharing the stage with Christophe Leterrier @christlet, who will talk about "The axonal cytoskeleton down to the nanoscale"🤩
#Twinning in action 🇪🇺
Very pleased to have participated and shared my #PhD work during the 2nd @TWIN2PIPSA Training School @Cambridge_Uni @ChemCambridge last week! 😀 @ClaudioGomesLab 🧑🎓🇵🇹🇬🇧