Raghav Ramabadran @BMSplice
Houston, TX Joined August 2017-
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Raghav Ramabadran retweeted
Discovered more than 30 years ago, CD40L antagonists are proving to be powerful autoimmune drugs. Learn more in a 2024 #SciencePerspective: scim.ag/4mQ5VG9 #ScienceMagArchives
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Raghav Ramabadran retweeted
In the more than 20 years since the term “microplastics” was first coined, a rapidly growing body of research has consistently shown how pervasive and problematic the pollutants have become. A 2024 #ScienceReview provides an overview of this research and the progress made in…
Raghav Ramabadran retweeted
Mitochondrial dysfunction in myeloid cells: a central deficit in autoimmune diseases: Trends in Immunology cell.com/trends/immunol…
Raghav Ramabadran retweeted
Excited to share the first paper from my lab in @Nature ! We repurposed the widely used research tool, proximity labeling, to demonstrate its therapeutic potential in antigen amplification for immunotherapy using mouse tumor models and patient samples. nature.com/articles/s4158…
Raghav Ramabadran retweeted
ABCA7 variants impact phosphatidylcholine and mitochondria in neurons nature.com/articles/s4158… @Nature
Raghav Ramabadran retweeted
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation bit.ly/47xeroJ
Raghav Ramabadran retweeted
Genome-wide mapping of RNA-protein associations through sequencing go.nature.com/4gmf1Ii
Raghav Ramabadran retweeted
For readers interested in cancer therapies, this review discusses how metabolic dysfunction of CD8 T cells and NK cells can diminish their anticancer activity, and assesses therapeutic strategies to overcome this nature.com/articles/s4157… rdcu.be/eFqm2
Raghav Ramabadran retweeted
Small peptide tags (like ALFA) cause minimal disruption of proteins, but typically lack fluorescence. Now fluorescent protein-fused ALFA nanobodies have been developed for knockin ALFA tag labeling of endogenous proteins nature.com/articles/s4158…
Raghav Ramabadran retweeted
Nature research paper: Metabolic adaptations direct cell fate during tissue regeneration go.nature.com/3FMlpe4
Raghav Ramabadran retweeted
Online Now! Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength dlvr.it/TLK9Q9 #stemcells
Raghav Ramabadran retweeted
OpenAI quietly dropped a 34-page technical manual on building AI agents that 99% of people will never read. I spent 3 days coding every single pattern they revealed. Here's the practical guide to autonomous AI agents:🧵
Raghav Ramabadran retweeted
Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵:
Raghav Ramabadran retweeted
How exercise protects the brain through neurovascular-associated astrocytes and neuroplasticity: Results of elegant single cell/nuceli studies in the experimental Alzheimer's model @NatureNeuro nature.com/articles/s4159…
Raghav Ramabadran retweeted
The "reasoning doesn't exist" Apple paper drives me crazy. Take logic puzzle like Tower of Hanoi w/ 10s to 1000000s of moves to solve correctly. Check first step where an LLM makes mistake. Long problems aren't solved. Fewer thought tokens/early mistakes on longer problems. 1/11
Raghav Ramabadran retweeted
A new epigenetic clock —DNAmIC—outperforms others for identifying risk of all-cause mortality, and linked with lifestyle and immune system factors @NatureAging nature.com/articles/s4358…
Raghav Ramabadran retweeted
New research in Science establishes #CRISPR-associated transposase (CAST) as a powerful platform technology for efficient, RNA-guided gene integration in human cells. scim.ag/3FgKo93
Raghav Ramabadran retweeted
An antibody directed to the NAD-degrading enzyme CD38 in mice restores metabolic fitness, improves cognitive performance & lowers neuroinflammation nature.com/articles/s4146…
Raghav Ramabadran retweeted
90% of doing science is being open to new ideas.
Raghav Ramabadran retweeted
An atlas of transcription factor-driven gene programs across human cells @teichlab biorxiv.org/content/10.110…
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