Bill Miller @BillMiller32
Private Doctor/Investor specializing in micro/small cap biotech-big believer in collaborative networks of fellow investors who can & do beat the institutions USA Joined November 2011-
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Positive Commentary re $AXSM ADA etc. Starts at 11.46 min ...Nice restatement of the obvious value & opportunity... $XBI $IBB biotechtv.com/post/mizuho-gr…
$AXSM 05's ACCORD P3 presented today at AAN x.com/MichaelOkun/st…
$AXSM 05's ACCORD P3 presented today at AAN x.com/MichaelOkun/st…
$CLRB coming back!
$AXSM Ph3 batting avg is great!-& even 1 TRD miss was close where maj error was prob running rel. small Tr(312pts) & expecting separation in such an obv unresponsive pt pop. Since TRD covered under gen. MDD approval, AXSM prob decided docs could figure this out w/o 2nd P3:-) $XBI
$AXSM Ph3 batting avg is great!-& even 1 TRD miss was close where maj error was prob running rel. small Tr(312pts) & expecting separation in such an obv unresponsive pt pop. Since TRD covered under gen. MDD approval, AXSM prob decided docs could figure this out w/o 2nd P3:-) $XBI
$tgtx I will repeat what I said not to long ago. CPI/inflation has nothing to do with Bruimvi sales. Any pullback imho is an opportunity for those who want to increase their position at a more advantageous price
$AXSM seeking an Associate Director to provide field medical support in Alzheimer Agitation. This person will be the 1st field medical hire supporting ADA & will be a key member of the Medical Affairs team at AXSM. Will be responsible for providing support for launch planning.
$AXSM in BED? Prim.rationale for Sol. in ADHD is precisely b/c it works w/o heavy SEs & abuse poten. of uppers like Vyvance, & SEs prob big part of why V not used much in BED-So,Sol. imo could be very big in ext. underserved mkt making tiny Tr invest. another AXSM bargain!:) $XBI
$AXSM in BED? Prim.rationale for Sol. in ADHD is precisely b/c it works w/o heavy SEs & abuse poten. of uppers like Vyvance, & SEs prob big part of why V not used much in BED-So,Sol. imo could be very big in ext. underserved mkt making tiny Tr invest. another AXSM bargain!:) $XBI
$AXSM Pipeline-focused with eyes on ‘24 catalyst prize: AXSM-05 Ph3 results 2H24. ~$1B Alzheimer’s Agitation market. AXSM-05 has better safety profile vs. front-running competitor, Rexulti, with black box warning for elderly pts. with dementia-related psychosis.
$AXSM Pipeline-focused with eyes on ‘24 catalyst prize: AXSM-05 Ph3 results 2H24. ~$1B Alzheimer’s Agitation market. AXSM-05 has better safety profile vs. front-running competitor, Rexulti, with black box warning for elderly pts. with dementia-related psychosis.
$NVCT validation will progress over the following months as additional screens reveal patient data. Clearance of lymph node, where OC metastasizes, very exciting. Nice institutional size bid sitting on the board this morning.
@BillMiller32 Funny how the large inflection we've been looking for to confirm Auvelity's BB Status all along comes at a time like this(Q1), when no one's really looking for it. Still, great to see😀! $AXSM
$AXSM Week 73 of the Auvelity launch), with IQVIA reporting 5,074 NRxs/8,056 TRxs (+39%/+38% w/w). This compares to last week's 3,654 NRxs/5,838 TRxs and for Auvelity, again according to IQVIA.
$AXSM RX #s? Todays massive RX bump confirms strength of Auvelity launch, partic. since comparative analogs didn't follow suit in bounce back from cyber attack slow down. Therefore, strong recovery from recent correction v. probable! x.com/kjerath/status… $XBI $IBB
$AXSM RX #s? Todays massive RX bump confirms strength of Auvelity launch, partic. since comparative analogs didn't follow suit in bounce back from cyber attack slow down. Therefore, strong recovery from recent correction v. probable! x.com/kjerath/status… $XBI $IBB
$AXSM s rapid turnaround from hi $60s to $73+ in minutes suggests some big investors concluded they’d, for lack of a better term, run out of “suckers” to buy from down here👻!Barring some maj unexpected bust, I suspect we’ve essentially seen the bottom of this sequence. $XBI $IBB
Jim-re $AXSM 05 in ADA, just a regurgitation of what we’ve known since Rexulti( w black box) approved for ADA last year-A little surprised, due to great 05 data & need, that FDA approved that 1st, but another Buy initiation today by UBS v.clear on +Tr & Approval odds in 2024👻!:)
Jim-re $AXSM 05 in ADA, just a regurgitation of what we’ve known since Rexulti( w black box) approved for ADA last year-A little surprised, due to great 05 data & need, that FDA approved that 1st, but another Buy initiation today by UBS v.clear on +Tr & Approval odds in 2024👻!:)
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311 Followers 502 Following Tech analysis / 15 year Options Swing Trader. Heavy focus on biotechs solving today's unmet needs. Will be launching https://t.co/rpq39Sxz9a soon$AXSM. From Morgan Stanley today. "Upgrading to OW on attractive risk/reward heading into 2H24, with PT up to $115. Following the recent pull back, we believe current levels provide an attractive entry point into AXSM ahead of a data readout that could unlock a significant .....
$AXSM Within next 2 months AXSM expects to submit AXS-07's migraine NDA & AXS-14's Fibromyalgia NDA.
I'm extremely bullish $AXSM and AX-05 has possibly to enter Alzheimer's agitation market without warning labels carried by current therapies
Positive Commentary re $AXSM ADA etc. Starts at 11.46 min ...Nice restatement of the obvious value & opportunity... $XBI $IBB biotechtv.com/post/mizuho-gr…
@BillMiller32 BILL; thanks for replying to my question about allocation of my limited equity between AXSM and VKTX. I decided last week to shift some $$$ from my VKTX to AXSM for one reason; while VKTX has a much higher ceiling than AXSM in a few yrs, my time line is fairly short term and AXSM
@BillMiller32 @arenella1 🙏🏻from your mouth to gods ears and to the board!
@BuyLowRetire The 8,300 # of scripts was the highest of any week for Auvelity since its launch began. IQVIA's TRX counts miss by about 8% so Auvelity was closer to 9,000 TRX last week.
$AXSM AAN Slideshow for 05's ACCORD data axsomecongresshub.com/pdf/AAN-2024-O…
@BillMiller32 Matter of time. Can’t believe @axsome doesnt have something positive to share with the market 🤔
Remaining short SPY, long VIX, and holding but not adding yet to individual biotech names. If I had $ to deploy, only one I would add is $AXSM b/c their target indications are expanding, sleep disorders and Alz big markets.
$AXSM New AEs with Antipsychotics use in dementia alzheimersresearchuk.org/news/antipsych….
$AXSM If you’re short, take note, the fat lady is warming up!
$AXSM seeking an Associate Director to provide field medical support in Alzheimer Agitation. This person will be the 1st field medical hire supporting ADA & will be a key member of the Medical Affairs team at AXSM. Will be responsible for providing support for launch planning.
$SPY what breaks first, ceiling or floor? For context see @dampedspring -- the "pivot" predicted in January was just a dream. I think those January lows get revisited. Short $SPY: $SPXU $SQQQ $SOXS: long $VIX options.
$AXSM 05's ACCORD P3 presented today at AAN x.com/MichaelOkun/st…
AXS-05 looks good in preventing relapses of agitation w/ Alzheimer’s. Presented this morning @AANmember. Data on primary outcome. We need more drugs to help this symptom so could be good news.
@biobetting TRD showed good efficacy and "miss" was on stat sig, which can be notoriously irratic. Auvelity probably safest drug for TRD and as good as, if not better, than ketamine based treatments. Ketamine is risky.
$AXSM
In a pooled analysis of 2 phase 3 trials, treatment with AXS-07 (@axsome) resulted in a significant reduction of #headache pain freedom, #migraine symptoms, and rescue medication use. #AANAM @AANmember neurologylive.com/view/pooled-ph…
@BillMiller32 Spot on. This is such an undervalued stock. They’re going to hit on ADA as well. They already hit in the phase 2. Don’t understand why the market doesn’t see this coming.
$AXSM owns a great CNS P3 batting average when compared to others in CNS. PFE & LLY dominated the sector until withdrawing due to PBO effect forcing larger P3s. AXSM has 2 sig stats in 2 MDD, 2/2 in migraine, 2/2 in AA and 2/2 in Narcolepsy w Cataplexy. Lone fail was TRD miss.
$tgtx I will repeat what I said not to long ago. CPI/inflation has nothing to do with Bruimvi sales. Any pullback imho is an opportunity for those who want to increase their position at a more advantageous price
$GMAB acquision of ProfoundBio -- if molecules under preclinical development can be attractive additions to an oncology portfolio, those that begin to demonstrate efficacy in humans against widely used drug (e.g. Tagrisso) resistant targets certainly are as well. $NVCT
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