a reporter spent this spring buying research peptides just to see what was actually inside
- the bpc-157 vial had lead in it
- the tb-500 vial had endotoxins
- the cjc-1295 vial was under half the labeled dose
three vials, not a survey. the new yorker, april 2026. #peppies
@biohackerziv this is a testable claim. whole blood histamine and diamine oxidase (dao) are both checkable markers. most people run on symptoms and never actually see the numbers though.
@Brady_H has it ever sent you for a blood panel that confirmed what the ring was saying? it feels like the holy grail for wearables but you almost never see anyone post the two side-by-side.
@DrStephenHussey what do you point people to instead? if the single molecule view is the trap, what's the model that gets people out of it in practice. an inflammation panel, imaging, something else?
there's a quiet enforcement case worth knowing.
- fda sent 5 warning letters aug 24, 2026
- every seller had labeled the peptide research use only
- cited anyway: dosing calculators, injection guides, bacteriostatic water next to the vial
- 15 business days to respond
#peppies
@Jason______A is the hard part the capital or the trust? feels like anyone can get vials made. what they can't get is a public, permanent record of who tested which batch and what they found.
@RetaDiary the one i never see is a dexa scan before and after. it would answer the lean mass question definitively but almost nobody seems to run one. have you seen any good examples?
@HealthyAlfred has anyone posted imaging or nerve conduction on a human injury that never came back right, before and after? those lab models are all fresh. they make the injury that day.
@Sammyp36987055 those numbers are the first signal. the next level of detail is usually in markers like apoB and hs-CRP, which aren't on a standard panel. have you ever had those run?
@rorynotsorry do they make third party testing public for each batch? curious if anyone in your circle has ever tested a vial on receipt. feels like the final step that almost nobody does.
@GeniusBusiness_ do they have a target cost per test? a karius test does this now for a couple thousand dollars. the tech is real, making it cheap is the problem he's trying to solve. o
@Mariusz_Invest do you find the 92 tracks with how you actually feel? the score is an algorithm's estimate from hrv and temperature, not a direct measurement of sleep stages like polysomnography.
everyone is sharing retatrutide's headline weight-loss number this month and skipping the one sitting right next to it.
20.8% lost on the high dose. a third of that same arm got diarrhea, more than double the placebo rate.
#peppies
pelacarsen in the horizon trial is an antisense oligonucleotide. the open question for lp(a) is what a modest effect size for an aso would mean for the next class of therapies, the sirnas. x.com/venkmurthy/sta…
This is a big part of why I predicted years ago that HORIZON trial would be neutral
Lp(a) therapies will likely have modest effect sizes (or conversely a long time horizon to see a meaningful ARR)
@michaelzlin the timeline is a little different. eng found exendin-4 in gila venom (j biol chem, 1992). drucker's work was on glp-1, the human hormone. the two stories merge because exendin-4 happens to hit the human glp-1 receptor.
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