The Body Explained | Anatomy, Physiology, Medicine @BodyExplained
Explore the wonders of the human body through bite-sized lessons on anatomy and physiology🫀🫁🩻⚕️clinicclips.substack.com United StatesJoined January 2024
Molecular mechanism of muscle contraction
▪️Action potential travels through the transverse tubule system & sarcoplasmic reticulum
▪️Ca ions is released
▪️Ca ions bind to troponin C
▪️Actin-myosin binding (requires ATP)
▪️Muscle contraction
#musclesciencedirect.com/science/articl…
👂 The eardrum (tympanic membrane)
•Thin, cone-shaped membrane separating external ear from middle ear
•Vibrates with sound waves → transmits energy via ossicles to the cochlea
•Innervation: auriculotemporal nerve (V3) & auricular branch of vagus (Arnold’s nerve)
🧵 Growth Hormone
💤Secreted by the anterior pituitary (somatotrophs) in a pulsatile fashion, especially at night.
Controlled by:
•GHRH (stimulates)
•Somatostatin (inhibits)
⚙️Main actions:
•Stimulates IGF-1 release from the liver → drives bone & muscle growth.…
💡When a supplement has been studied for decades, across thousands of trials, in both men and women, you pay attention.
That's Creatine Monohydrate.
Recognized as one of the safest, most effective performance aids in existence, creatine goes far beyond the barbell.
🥼WHAT…
🔥FEBRILE STUFF 🔥
BMS Wednesday 🙋🏾♀️🙋🏾♂️📚
Houston Valves of Rectum
💥The valves of Houston, also known as transverse rectal folds, are permanent semilunar folds within the rectum.
💦🧂Aldosterone
📍Secreted from the zona glomerulosa of the adrenal cortex.
Release is triggered by:
-Low blood pressure (via renin–angiotensin–aldosterone system)
- High Potassium levels
-ACTH (minor role)
⚙️Main actions:
-Acts on the distal nephron (collecting ducts &…
🧬 Anti-Müllerian Hormone (AMH)
Secreted by Sertoli cells in males → causes regression of Müllerian ducts (prevents uterus, fallopian tubes, upper vagina).
In females, produced by granulosa cells of ovarian follicles → reflects ovarian reserve.
👉 Clinically used in…
🧪 D-dimer = fibrin degradation product
•Elevated when clots are being formed & broken down.
•Useful to rule out VTE (DVT/PE) if clinical probability is low.
•Not specific → also ↑ with infection, inflammation, cancer, surgery, pregnancy.
👉 High D-dimer ≠ always a…
Heartburn that doesn’t quit isn’t just annoying, it can change the esophagus itself. 🔥➡️🟠
Learn below how chronic GERD leads to Barrett’s esophagus and why it raises cancer risk.
open.substack.com/pub/clinicclip…
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