BüttnerLab @ButtnerLab
We are yeast and fly enthusiasts interested in different aspects of cellular aging and organellar connectivity. Account run by lab members. buttner-lab.com Stockholm, Sweden Joined January 2021-
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Join us for the DGZ Focus Workshop “Membrane Organization and Contact Sites” on Tuesday, March 25, 2025. Zoom-ID and passcode available in the flyer. Don't miss it!
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BüttnerLab retweeted
TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport nature.com/articles/s4146…
BüttnerLab retweeted
Evolutionary origins of the lysosome-related organelle sorting machinery reveal ancient homology in post-endosome trafficking pathways | PNAS pnas.org/doi/10.1073/pn…
BüttnerLab retweeted
So happy to finally see this out! Great work by first authors @A_STEDhammer and @petiaadarska which have shown that cargo flow along post-Golgi routes is driven by a key maturation step where compartments defined by ARF1 nature into recycling endosomes nature.com/articles/s4155…
BüttnerLab retweeted
Image summarizes the observations by Smith, Gay, and Babst @UofUBiology proposing a new function for the tricalbins: mediating the fusion of the ER to the plasma membrane at contact sites. hubs.la/Q02QBxc40 #Membrane #lipid #Trafficking #Biochemistry #ER_literature
BüttnerLab retweeted
In a special seminar on Monday, October 07, at 12:00, @sfb1348 will host Sabrina Büttner @ButtnerLab, who just joined @uni_muenster. Welcome to our scientific community! Don't miss Sabrina's seminar on Organelle connectivity during cellular aging and metabolic adaptation!
BüttnerLab retweeted
An exciting story from the lab! The balance of ceramide-glycerolipid synthesis in the ER regulates Caveolin1 localization. This is dependent on seipin, organizing #lipiddroplet formation. #Golgi #Caveolin1 #ER_literature #Diatetes #Metabolicdisorders biorxiv.org/content/10.110…
BüttnerLab retweeted
Our new paper: Misfolded proteins activate HSF1 by releasing it from Hsp70. This has been clear in yeast for some time and we find that the mechanism is similar in human cells. sciencedirect.com/science/articl…
BüttnerLab retweeted
Wilson, @Adam_L_Hughes et al. observe that mitochondrial-derived compartments selectively incorporate proteins from only the outer mitochondrial membrane (OMM) and robustly sequester both excess and mistargeted proteins into this OMM-enriched domain. hubs.la/Q02L7pSP0
BüttnerLab retweeted
🥂Thrilled to see my latest #postdoc work out! What began as a quick, fun side project just before the first lockdown led me down a rabbit hole and ended in @NatureCellBio 4.5y later: nature.com/articles/s4155… #autophagy #polyamines #fasting #caloricrestriction🧵1/11
BüttnerLab retweeted
Posor & Haucke discuss the recent study by @JasonCasler, @LLLackner et al. @LacknerLabNU (hubs.ly/Q02JyKd30) describing how tripartite membrane contacts btwn #mitochondria, ER & plasma membrane regulate mitochondrial division & PI(4)P metabolism. hubs.ly/Q02JyTBm0
Very excited to participate in this "Membrane Contact Sites in Cellular Homeostasis" meeting in Edinburgh. Earlybird registration and abstract submission closes the 23rd of July. Don't miss it! bit.ly/Membrane24
BüttnerLab retweeted
#MembraneContactSite community: Do not miss July 23, the earlybird registration deadline for our “Membrane Contact Sites in Cellular Homeostasis” @BiochemSoc meeting in Edinburgh. Submit an abstract by then for being considered for a short talk! bit.ly/Membrane24
BüttnerLab retweeted
Great to see our preprint out. We uncovered a simple likely mechanism to fuse inner+outer nuclear envelopes to precede nuclear pore complex (NPC) insertion. Our first step was to show that CLCC1 is the long-lost human homologue of Brl1 (previously only known in yeast, protists)
Great to see our preprint out. We uncovered a simple likely mechanism to fuse inner+outer nuclear envelopes to precede nuclear pore complex (NPC) insertion. Our first step was to show that CLCC1 is the long-lost human homologue of Brl1 (previously only known in yeast, protists) https://t.co/3bSujVODXl
BüttnerLab retweeted
Finally out! Unsaturated lipids regulate the growth of the apoptotic pore 🍩 @ShashankDadsena @CECAD_ link.springer.com/10.1038/s41467…
BüttnerLab retweeted
Two weeks left to register for the 8th EMBO/FEBS lecture course on “Mitochondria in life, death and disease” (16-20 September). Amazing line-up of speakers and many possibilities for early career scientists to discuss science and career paths. #EMBOmitochondria #mito
BüttnerLab retweeted
We are proud and excited to share the new study from our lab, led by the amazing @RanenAviner. It uncovers an important pathogenic mechanism causing cellular dysfunction in Huntington's Disease. We hope this work will inspire new and effective therapies nature.com/articles/s4155…
BüttnerLab retweeted
A breakthrough from the lab! A game-changer and the dawn of a new era in membrane and organelle biophysics and biology. We've generated giant organelle vesicles #GOVs with conserved biochemical activity. @AgenceRecherche @LP_ENS_ @ENS_ULM @NatureComms nature.com/articles/s4146… 1/6
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