Del Valle Lab @DelValleLab
Organic synthesis and chemical biology lab at Notre Dame... Putting the 'PEP' in peptides. delvallelab.weebly.com Notre Dame, IN Joined June 2019-
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New Acc. Chem. Res. from the lab dropped online yesterday: pubs.acs.org/doi/10.1021/ac…. Right on first author Isaac's birthday, and one day before second author Madi's birthday. Practically twinsies! Happy bday guys! 🎂
Huge week for 5th year @b_raj12. Thesis defense, Dow outstanding grad student award, and birthday to boot! Congrats Ben! 🥂
At last... we're thrilled to send our story on macrocyclic mini-tau seeds out into the world. Organic chem, protein mimicry, cryo-EM, cell function; something for everyone! Congrats to Isaac & Xueyong, and collabs from Purdue and IUSM! chemrxiv.org/engage/chemrxi…
Congrats to Isaac Angera for taking home a 2nd place poster award at the 2024 Peptides GRC!! Well-deserved! Stay tuned for more on his exciting foray into "mini-tau" macrocycles.
#OnTheCover Stabilizing Pseudouridimycin: Synthesis, RNA Polymerase Inhibitory Activity, and Antibacterial Activity of Dipeptide-Modified Analogues (ChemMedChem 1/2024) (J. R. Del Valle et al.) @DelValleLab onlinelibrary.wiley.com/doi/10.1002/cm…
4 new group members this month! Thrilled to welcome postdoc Abha Dangi, and 1st year grad students Ana-Teresa Mendoza, Alexandre Renon, and Fadwa Kamari. Welcome to the team!
Had an amazing time at the Purdue University Notre Dame Symposium (PUNDS). There were so many great talks/research being done from each university. With that being said, I am honored to receive the Best Presentation Award for my talk!
Hats off to Theo and Natalia, who passed their candidacy exams this month!👏🎉 Cake, coats, and congrats on job well done!!
Almost the end of #AusPeptide2023 sadly! Thank you all for coming and having a great time, giving amazing presentations and presenting fantastic posters. Hope to see everyone again soon! 🇦🇺👀🧪
Excited to share our story on cross-beta epitope mimics targeting tau propagation, out now in @J_A_C_S. Grateful to all involved on this project, and a special congrats to first author @b_raj12!! pubs.acs.org/doi/10.1021/ja…
Check our latest pub describing stabilized PUM analogues. Congrats to @Avraz__Anwar, Chris, and Michael Garza; and our collaborators in the @R_H_Ebright lab! doi.org/10.1002/cmdc.2…
...and, as promised, here is the organic teaching faculty ad! apply.interfolio.com/130939.
...and, as promised, here is the organic teaching faculty ad! apply.interfolio.com/130939.
Congrats to our very own @tagerrein for passing his candidacy exam on Friday!! Got a chance to celebrate in the sun at ND Chemfest later that day...
ND Chem & Biochem is hiring! Tenure-track faculty position in Organic Chemistry: apply.interfolio.com/129030 Spread the word. (...and be on the lookout for a separate organic teaching faculty ad, coming soon!)
Way to go @Avraz__Anwar and @mikegz_ !
Grateful for an inspiring lecture from the incomparable @CarolynBertozzi at #NOS2023ND!
Early registration for #NOS2023ND ends this week on June 15, so register now! This year’s Roger Adams Award winner, Professor @CarolynBertozzi of @StanfordUChem will discuss her work in bioorthogonal chemistry. Not to be missed! nationalorganicsymposium.org @ACSorganic
Our story on polyproline II stabilization with derivatives of N-aminoglycine is now out in @JOC_OL. Awesome team effort from Ben, Madi, and Taylor!! pubs.acs.org/doi/10.1021/ac…
Huge congrats to 2nd year grad student @Avraz__Anwar for being awarded an CBBI fellowship through our NIH T32 program! Way to go Avraz!
Nick Chiappini 🏳�.. @ndchiappini
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19F NMR tools: Zondlo and colleagues show that 4,4-difluoroproline is a broadly applicable tool for monitoring Pro conformation with applications in protein folding, intramolecular interactions and intrinsic disorder. pubs.acs.org/doi/10.1021/ac… #folding #disorder @UDelaware
Congratulations to our brilliant postdoc @morimoto_mari, joining the fantastic faculty @NotreDame next year 🎉 🍾 🥂
Excited to share that I'll be joining the Department of Chemistry and Biochemistry at the University of @NotreDame as a Huisking Foundation Assistant Professor in January 2025! My lab will develop chemical tools to retrain our immune system in cancer, autoimmunity, and more.
Excited to share that I'll be joining the Department of Chemistry and Biochemistry at the University of @NotreDame as a Huisking Foundation Assistant Professor in January 2025! My lab will develop chemical tools to retrain our immune system in cancer, autoimmunity, and more.
We @Yichun_Wang_Lab are glad to share a preprint on @ChemRxiv with @WebberLab - "Sensitive Fluorometric Detection of Fentanyl-Class Agents by Competition-Mediated Supramolecular Displacement and Graphene Nanoparticle Quenching." chemrxiv.org/engage/chemrxi…
Thank you for organizing such a fantastic day, @AnnaMapp! It was really great meeting faculty, students and postdocs @MichiganChem 🙏
Delighted to welcome @NinaHartrampf to @MichiganChem tomorrow (Friday) to tell us about her innovative work in peptide and protein synthesis! If you are in Ann Arbor, this is not a seminar to miss.
Let me introduce you to these superstar @CarletonCollege students who have read 200(!) of my papers, distilled them to a lecture, prepared 17 pages of questions, and engaged me in two days of most stimulating discussions! An extraordinary talented group of young scientists!
I’m currently in the Midwest for a couple of department visits. Thank you for inviting me to @NotreDame earlier this week, Juan @DelValleLab 🙏 I had a really great time meeting everyone ☺️
Thankful for this recognition. All credits go to my group's past and present members; I have been truly fortunate to work with them!
Congratulations to the winner of the 2024 Bioconjugate Chemistry Young Investigator Award, Professor Abhishek Chatterjeee, Boston College. #chemistry #award @BostonCollege @AChemSynBio @ACSPublications tinyurl.com/my3a3jxk
Our paper on tau and amyloid beta in Down syndrome is out! We hope this data can lead to the inclusion of people with Down syndrome in Alzheimer's disease clinical trials nature.com/articles/s4159…
A study led by Ruben Vidal, PhD, from the Indiana University School of Medicine finds similar protein structures in Alzheimer's and Down syndrome, suggesting common mechanisms with implications for treatment development: bit.ly/49gAw80
Useful site for funding FY2024: NIA +2.2%, NIDDK +4.8%, NCI +1.7%, NIEHS -7.7%, NIMH -2.9%, NINDS -4.3%, remaining institutes flat aaas.org/news/fy-2024-r…
I am happy to announce that I was awarded with the 2024 Meienhofer Award from the Boulder Peptide Society (USA) in recognition of my lifetime of achievement in peptide science. Thanks to all my co-workers and colleagues @EurPepSoc @ampepsoc @AusPeptide
Two simple reagents, HCHO and hexafluoroisopropanol (HFIP), unleash new chemical magic! HCHO effectively “sucks” the alpha C-H bond from common alkyl amines in HFIP solvent, enabling hydride liberation without metals or light. It works for complex systems, too.
Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol @J_A_C_S #Chemistry #Chemed #Science pubs.acs.org/doi/10.1021/ja…
Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol @J_A_C_S #Chemistry #Chemed #Science pubs.acs.org/doi/10.1021/ja…
Four @schepartzlab members attend 2024 Peptides GRC...four win Best Poster prizes! Congratulations to (left to right) Isaac Knudson, @NoahXHamlish, @MaddieZoltek, and @leahtangroe!
So proud of our postdoc @elysetwilliams who was awarded a poster prize at the ‚Chemistry and Biology of Peptides GRC‘ in Ventura 🤩 We had a great time at the conference - looking forward to the next one in 2026!
Our collaborative study with the @SwansonGroup_UT made the cover of @J_A_C_S ! 'Lasso peptides: exploring the folding landscape of Nature’s smallest interlocked motifs' Cover art by Addison Cooper, Cooper Graphics. @UtahChemistry @uofu_science @UUtah read a summary:…
Super excited to share the news that I have been promoted to Full Professor of Chemistry. Nine years of roller coaster journey from Assistant Professor to Full Professor. Thanks to all the past and current members of @TheRajLab1 for making it possible.
I'm happy to share that Tufts' trustees have approved my promotion to full professor (effective this July)!
Congratulations to Dr. Joel P. Schneider of our Chemical Biology Laboratory for receiving the 2023 Biopolymers Murray Goodman Memorial Prize on behalf of the @AmerChemSociety! 👏 @theNCI
Congratulations to my amazing Team @Yichun_Wang_Lab @RunyaoZhu @Hjeon2Jeon @GaeunK1m , James Johnston, and @YouwenZhang_Lab - we are looking forward to developing the new therapeutic nanomaterials and training future scientists and engineers.
Prof. Yichun Wang @NotreDame @NDCBE has received an @NSF CAREER award! Her research focuses on the development of nanotherapeutics through computational, experimental and data-driven methods. Read ⬇️⬇️ engineering.nd.edu/faculty/yichun…
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