Embryo models @Embryo_models

Scientific updates on stem cell-based embryo models. Sharing new methods on the incredible process of mammalian embryonic development in-a-dish! Joined December 2022

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Jacob (Yaqub) Hanna - يعقوب حنا @jacob_hanna

2 years ago

1/n New Hanna lab PREPRINT: "Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naive PSCs" biorxiv.org/content/10.110…

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Magdalena Zernicka-Goetz @ZernickaGoetz

2 years ago

Thank you so much, Angela. I hope only that the press will report it correctly as the paper is not out yet. Any these are not embryos but embryo models made from stem cells.

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Embryo models @Embryo_models

3 years ago

Deciphering mouse placenta development: Single-cell transcriptomics reveals a differentiation roadmap of trophoblast cells from E7.5 to E14.5. nature.com/articles/s4142… #PlacentaDevelopment #SingleCellTranscriptomics"

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Embryo models @Embryo_models

3 years ago

Mouse trophectoderm stem cell (TSC) protocol paper from the Rivron lab. The combination of LPA, IL11, BMP7, Activin-A and 8Br-cAMP maintains the TSC stage more similar to the blastocyst trophectoderm. sciencedirect.com/science/articl…

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Heidar @HK_Heidar

3 years ago

Happy to share our detailed protocol for the generation of human blastoids modeling blastocyst-stage embryos and implantation, now out in @NatureProtocols rdcu.be/c5HA1 @NRivron lab @IMBA_Vienna @viennabiocenter [1/12]

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Embryo models @Embryo_models

3 years ago

Using the spliceosome and splicing inhibitor Pladienolide B to form blastomere-like cells that efficiently form blastoids, albeit with low number of PrE cells: pubmed.ncbi.nlm.nih.gov/36633710/

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Embryo models @Embryo_models

3 years ago

Interesting study on the more efficient generation of ETX embryoids by genetically inducing Fgfr2 along with Gata6 to speed up PrE identity reinforcement.

Zwijsen Lab @AnZwijsen

3 years ago

Interesting study on the more efficient generation of ETX embryoids by genetically inducing Fgfr2 along with Gata6 to speed up PrE identity reinforcement.