Sebastian Geibel @GeibelLab
#structuralbiology of type VII secretion systems. Leiden Institute of Chemistry Leiden, Netherlands Joined July 2019-
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Sebastian Geibel retweeted
Here is our recent work on T7SSb LXG effectors and the proteins that are required for their secretion. Thank you to everyone that contributed to the work and to @mbiojournal for the valuable reviews and speedy publication. journals.asm.org/doi/10.1128/mb…
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Sebastian Geibel retweeted
So excited to finally share these results of my 7 years effort. Thanks the whole @MarlovitsLab team for great support and esp. @DirkFahrenkamp, @nikigoessi! This was a wild ride... starting with a simple question. How does the complex move the DNA - lever is the answer. SOUND ON!
So excited to finally share these results of my 7 years effort. Thanks the whole @MarlovitsLab team for great support and esp. @DirkFahrenkamp, @nikigoessi! This was a wild ride... starting with a simple question. How does the complex move the DNA - lever is the answer. SOUND ON! https://t.co/tLN39LMPdO
Sebastian Geibel retweeted
How Escherichia coli Became the Flagship Bacterium of Molecular Biology @JBacteriology MiniReview by Natividad Ruiz and Thomas J. Silhavy journals.asm.org/doi/10.1128/jb…
Sebastian Geibel retweeted
Today in partnership with @emblebi, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: dpmd.ai/AF-22-TW 1/
Sebastian Geibel retweeted
Check out our collaboration with Anton Zavialov's group and others on the zigzag spring-like structure of an archaic chaperone-usher pilus in @Nature: doi.org/10.1038/s41586… Congrats to @NPakharuk, Henri Malmi and all authors!
Sebastian Geibel retweeted
Last days for abstract submission. Show us your cool science at the event. In particular encouraging ECR as well!!!
Last days for abstract submission. Show us your cool science at the event. In particular encouraging ECR as well!!!
Sebastian Geibel retweeted
In a recent Science study, researchers present a near-atomic composite structure of the human #NuclearPoreComplex’s ~64-megadalton symmetric core. The findings provide a basis for future functional studies. fcld.ly/wgoa4cj
Sebastian Geibel retweeted
Excited to finally share our story on the central role of PPE68 in ESX-1 secretion. I hope you enjoy reading it! #T7SS #mycobacterium
Excited to finally share our story on the central role of PPE68 in ESX-1 secretion. I hope you enjoy reading it! #T7SS #mycobacterium https://t.co/cGCSVrLf0m
Sebastian Geibel retweeted
Finally Online our paper on the molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation. Great team effort and fantastic collaboration with the Garnett group and Pau Bernadó nature.com/articles/s4152…
Sebastian Geibel retweeted
Here is the first preprint from our lab - which was only possible via a number of fantastic collaborations @FedorovaLab @PrattGroup @GarciaSaez_Lab @Conrad_Lab and a number of tweeterless colleagues. Please check this out and let us know what you think! #ferroptosis #preprints
Sebastian Geibel retweeted
We still have a fully-funded Ph.D. position open. If you are interested in developing antibody-based strategies to trigger ferroptosis in B-cell malignancies and exploit them in the context of immunotherapies - please get in touch. Previous mouse work exp is a plus!
Sebastian Geibel retweeted
Short term postdoc position available to work on the Tat pathway! Please RT jobs.ncl.ac.uk/job/Newcastle-…
Sebastian Geibel retweeted
@DanGrabarczyk @clausen_lab @OlgaPetrova127 @Real_Dr_Kessler @nchembio When did you leave the RVZ?😅 Congrats!
Sebastian Geibel retweeted
Just out.. our paper with brilliant collaborators @lab_baum @BaumBuzz showing ESCRT-III-like membrane remodelling proteins in bacteria… #Vipp1 #PspA 😎 cell.com/cell/fulltext/…
Sebastian Geibel retweeted
Identification and structural characterization of highly-resistant Gram positive pili at the surface of Bacillus cereus endospores. @RemautHan 's lab embopress.org/doi/abs/10.152…
Sebastian Geibel retweeted
Type VII secretion systems: structure, functions and transport models In this Review, Rivera-Calzada et al. provide an overview of the architecture of T7SSs, their functions and transport models nature.com/articles/s4157… @LlorcaLab @CNIOStopCancer @GeibelLab
Sebastian Geibel retweeted
Great to see the #cryoID of Endospore Appendages from pathogenic Bacilli out in @embojournal embopress.org/doi/abs/10.152… Built to last where others perish. Amazing architecture and self-assembly properties that results in flexible yet extremely resilient protein nanofibers.
Sebastian Geibel retweeted
We are very happy to make visible our review: “Understanding the invisible hands of sample preparation for cryo-EM” celebrating Protein Data Base 50th: the future of structural biology rdcu.be/ckjy8
Sebastian Geibel retweeted
Excited to share our research on bidirectional promoters in @NatureMicrobiol today! Here we show that transcription in bacteria isn't as 'straightforward' as we thought... 🧵 nature.com/articles/s4156…
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