MS-STAT2 @MsStat2
Updates and insight on the MS-STAT2 study from the team at UCL. A phase 3 clinical trial of high dose simvastatin for secondary progressive multiple sclerosis ms-stat2.info London, England Joined April 2019-
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Today the results of the MS-STAT2 trial were announced by Professor Jeremy Chataway at the ECTRIMS research conference in Copenhagen. This trial tested simvastatin, commonly used to treat high cholesterol, in 964 people with secondary progressive MS. (1/6)
Registration and abstract submission are open for MS Frontiers conference! This year the MS Society are hosting their MS research conference at the University of Liverpool. Find out all about it and how to register via their website: mssociety.org.uk/research/for-r…
Thank you @StuStepsUp+Marie for inspiring work @mssocietyuk @mscymru Ambassadors for people with #MS #AdvancedMS Check out chariotms.com #ChariotMS @QSMSCENTRE @MsStat2 @OctopusTrial @AttackMS_trial @the_MSBlog #MS @RachelHorne19 @themsguide @aid4disabled #NHS75 #GIG75
Thank you @StuStepsUp+Marie for inspiring work @mssocietyuk @mscymru Ambassadors for people with #MS #AdvancedMS Check out chariotms.com #ChariotMS @QSMSCENTRE @MsStat2 @OctopusTrial @AttackMS_trial @the_MSBlog #MS @RachelHorne19 @themsguide @aid4disabled #NHS75 #GIG75
Excellent @EANeurology #EAN2023 update on our expanded knowledge of #MS CNS compartmentalised inflammation and the exciting near future of BTK Inhibitors by Wallace Brownlee, Veronica Popescu and Martin König @DrWBRO @VeroPopescu
Great to be in Budapest for #EAN2023 discussing PIRA, compartmentalized CNS inflammation and BTK inhibitors with Veronica Popescu and Marton König @VeroPopescu @EANeurology
What is MS progression? Our understanding of progress independent of disease activity (PIRA) has grown over the last 20 years, with clinical and real world studies confirming that once relapses are controlled with DMTs progression can still happen!
An excellent overview of #SMOULDERINGMS - how we see progression independent of relapses #PIRA, what processes are involved and what #biomarkers will let us ultimately lead to individualized treatment!
#BrainAtrophy and #CognitiveImpairment in #MS - Closely interlinked, and of great importance to PWMS. Cognitive impairment being associated with more care needs and worse quality of life - focus on slowing/stopping this is essential!
#BigData in #MS - a great overview of the incorporation of all the -omics (genomic, metabolomics, proteomics, etc) towards novel understanding and treatments for #PMS #ProgressiveMS
The European Academy of Neurology 2023 conference! Let's talk #MS #BigData #Biomarkers #SmoulderingMS #clinicaltrials #PIRA and much more!
Hot off the press! The first STAT2 research paper - Cardiovascular Risk Factors in SPMS and how they impact brain volumes and memory. onlinelibrary.wiley.com/doi/full/10.11… Thank you to all our participants for their time and contribution!
#MSAwarenessWeek - how does MS make you feel? Does it affect you personally, or someone you know? Our amazing colleague Dr Alessia Bianchi @alessia_bia completing the London marathon to fundraiser for the @mssocietyuk! If you'd like please donate via: 2023tcslondonmarathon.enthuse.com/pf/alessia-bia…
Higher serum neurofilament light chain (sNfL) is linked to more cognitive decline in MS. Data from the MS-STAT study (simvastatin vs. placebo in progressive MS) pubmed.ncbi.nlm.nih.gov/35946107/
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial - PubMed pubmed.ncbi.nlm.nih.gov/35946107/
How did we recruit all our fantastic volunteers with SPMS for the MS-STAT2 and MS-SMART trials?? How can we make it better?! All in here if interested 👇 trialsjournal.biomedcentral.com/articles/10.11…
Fantastic to have team MS-STAT2 at #MSFrontiers! Congratulations to @mssocietyuk for a brilliant conference in beautiful Swansea!
Rachael Hunter presenting fascinating but quite shocking data on the impact of #SPMS on employment and quality of life for people in MS-STAT2. This is why we need treatments!

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