Parth Shah @ParthSharesBio
Biotech exec sharing views on biopharma | Passionate about #leadership and advancing medicines to reach patients | #RareDisease | Tweets are my own | 🤝 linkedin.com/in/parthrshah California, USA Joined September 2013-
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As competitive as oncology if not more on the high side…#immunology #oncology #biotech #pharma #drugdevelopment
As competitive as oncology if not more on the high side…#immunology #oncology #biotech #pharma #drugdevelopment
Biotech Consolidation: Not Really Happening. After two years of talk, that appears to be all it is right now… talk. Net numbers of publicly traded biotech down only 4.5%, hardly significant. lifescivc.com/2023/11/biotec…
One of the most powerful things we do at Amgen is to take the time to celebrate our shared mission for patients and recognize the work that we all do matters. Truly an inspiring day being with our team and hearing directly from the patients we serve. #AmgenMissionWeek #mycompany…
We set up the molecules in our portfolio as little companies and each one of those companies has a leadership team and board of directors. And they'll meet whenever they need to—and that's the way we provide the governance instead of the teams coming to committees for approvals.
RNAi (Alnylam), ASO (Ionis), Human Mabs (Regeneron), rDNA (Genentech, Biogen, many others)… Platforms are the only way to achieve sustainable innovation.
RNAi (Alnylam), ASO (Ionis), Human Mabs (Regeneron), rDNA (Genentech, Biogen, many others)… Platforms are the only way to achieve sustainable innovation.
2023 Orphan Drugs: PDUFA Dates and FDA Approvals Click on the link below👇 to view the list of important regulatory dates for all orphan drugs for 2023. checkrare.com/2023-orphan-dr… #rarediseases #drugapprovals
The lessons we learn over and over.
The “Innovation Reduction Act?” An inspiring story by Dr. Ted Love. The #InflationReductionAct has some laudable provisions, but others that threaten to chill investment in the new #medicines we and our loved ones all need.
The “Innovation Reduction Act?” An inspiring story by Dr. Ted Love. The #InflationReductionAct has some laudable provisions, but others that threaten to chill investment in the new #medicines we and our loved ones all need.
Great contrarian take on eNPV in #drugdevelopment . But this is where the people and process beyond the data are critical in these high stakes decisions. The best leaders know when to take the eNPV off the table, or use it as an extra data point at most. You can often make a…
Great contrarian take on eNPV in #drugdevelopment . But this is where the people and process beyond the data are critical in these high stakes decisions. The best leaders know when to take the eNPV off the table, or use it as an extra data point at most. You can often make a…
An important #FDA consideration if you are navigating upcoming #clinicaldevelopment in #RareDisease. Double edge sword as some of cross disease instruments may not yield all the disease specific nuances. Looking forward to more updates about the endpoint advancement program...…
Development and commercial odds are tough which is why the mission/vision is so critical —> the inspiration to do the unimaginable isn’t just make believe - time and again , we have seen that if you can stay in the commercialization fight, you’ll land some blows, but the team…
Development and commercial odds are tough which is why the mission/vision is so critical —> the inspiration to do the unimaginable isn’t just make believe - time and again , we have seen that if you can stay in the commercialization fight, you’ll land some blows, but the team…
AstraZeneca will buy up a group of early-stage gene therapies from Pfizer, bucking a trend of drugmakers axing programs and exiting a field that had once captured the imagination — and checkbooks — of many pharmaceutical executives. trib.al/78WHgKb
Better use of digital and data in rare disease commercialization go hand in hand. However, applying judgment to these levers and creating an intentional strategy and org design to execute is the tough part (my brief take 👇). #pharma #biotech mckinsey.com/industries/lif…
Great clip from @chamath describing who the ultimate financial winners may be from the generative AI revolution
Came across NaviHealth recently denying care to a 33-year old mom with a rare ovarian cancer. Drug was working but new #PBM using NaviHealth denied it. Report in @statnews @caseymross @bobjherman statnews.com/2023/03/13/med…
#Hospitals took $28 Billion in tax-exemptions for charity care but delivered only $16B in care-while they set collectors on indigent patients who couldn't afford their bills. Why are @POTUS & #Congress not exercised about this? #healthcare #costs
#Hospitals took $28 Billion in tax-exemptions for charity care but delivered only $16B in care-while they set collectors on indigent patients who couldn't afford their bills. Why are @POTUS & #Congress not exercised about this? #healthcare #costs
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Reading Between the Transaction Timelines by Cantor **2023 Acquisitions Maintains that Many Deals Are Competitive
New professor walking to lecture on her first day of class. Wish me/them luck! (But mainly me)
Do NOT jump from an MBA to try to start your own biotech company. Do NOT jump into a small start up. Do NOT skip experience in a big biotech (where you will learn from great people) and think you can develop drugs when you’ve never seen it done. 🧵7
Do NOT rush and miss out on the experience you need to be successful! Experience is PRICELESS! Hope this helps! John P.S. Also, don’t do virtual or hybrid “work!” Be on site!!! 🧵8/8
Bob Bradway announced today that I have joined his leadership team as Executive Vice President of R&D, and Chief Scientific Officer @Amgen. I am overjoyed by the opportunity to create and develop therapeutic solutions for patients with serious illnesses. Here are some additional…
We’re announcing two changes to Amgen’s senior leadership team that will keep our company at the forefront of innovation. @jaybradner, M.D., joins as EVP, R&D, and Chief Scientific Officer. David M. Reese, M.D., will assume a new role as EVP and Chief Technology Officer.…
Let’s go! @Amgen #MyCompany
No wonder my day was super busy with investors wanting to schedule meetings 🤦♀️ #JPM24 #biotech #medtech #InvestorRelations
The preliminary #JPM24 schedule is out.
My PhD advisor and an amazing mentor. Learned so much from him, not just about science but life in general. Sad day. RIP.
A major loss for all of us. Allan Hoffman (1932-2023) Univ_Washington passed away today. Allan was my academic brother (PhD '57 MIT) and great mentor. Devastated. He was such an inspiration to all of us. All in tears after we received the news about an hour ago. RIP.
completed $148M raise ($125M offering, $23M private placement with @EliLillyandCo) post raise, 3y cash runway, now into late 2026. @VerveTx $VERV ir.vervetx.com/news-releases/…
Biotech startups with a large pharma investor/licensor have a higher success rate (32% vs 18% aquisition/IPO/FDA approval rate) and higher valuations, as measured by current market capitalization (median $332M vs $138M market cap; median $337 million vs $138M acquisition value).
How large pharma impacts biotech startup success. Implications for bioentrepreneurs go.nature.com/3djFeZm rdcu.be/cgdw5
@LifeSciVC Biopharma is unconcentrated to begin with, vs other sectors...and there are *tons* of companies! Interesting that the # of companies is relatively stable Y/Y (-4.5%) vs >20% reduction for the GFC. There's prob more consolidation in mkt cap terms, but that's harder to pin down.
Biotech Consolidation: Not Really Happening. After two years of talk, that appears to be all it is right now… talk. Net numbers of publicly traded biotech down only 4.5%, hardly significant. lifescivc.com/2023/11/biotec…
Today I started a new role as EVP, Investments at Enavate Sciences (part of Patient Square Capital). I'm thrilled to be working with the stellar team at Enavate to identify new biopharma investment opportunities, and w/ the talented entrepreneurs at their portfolio companies!
Last 5 years @VerveTx What will next 5y bring? Super excited for path ahead with our team
A common theme in my work with biotech leaders is tough conversations. How can you confidently have a tough conversation in which you openly ask for what you need without damaging your relationship with the other person? I've written a long thread with a step-by-step framework…
🚀Coming soon: All my most loved articles and guides on biotech leadership in a single book! 📕 Boy, have I written a lot this year! Endless hours of researching, writing, editing, re-editing… And now, putting all these writings into a book hasn’t been easy either! I wasn’t…