Global Bio x AI Community. A third place for scientists, product managers, computational biologists, engineers and academics working in AI & Software for Biolinktr.ee/techbiotransfo… GlobalJoined August 2024
💥 We're hiring our first research scientists for OpenAI for Science!
As a reminder, our goal is to build the next great scientific instrument: an AI-powered platform that accelerates scientific discovery.
Antibody design may be just about to leave its “spray‑and‑pray" era.
Chai‑2 reports ~50% de‑novo hits incl. sub‑nM.
IgGM, Germinal, PXDesign join the push.
Mosaic + AIntibody/BenchBB makes it testable.
The bottleneck seems to be clean affinity data.
A Large-Scale Pharmacogenomic Knowledge Graph for Drug-Gene-Variant-Disease Discovery
1. This preprint presents a large-scale pharmacogenomic knowledge graph (PGx-KG) integrating multiple databases to enable the discovery of drug-gene-variant-disease relationships. The graph…
(New thesis) AI-ification of R&D proteins
There’s been an emergence of new papers on computational antibody, peptide, nanobody, and and enzyme design. While these are all relevant for new therapeutics, there’s massive market opportunity in R&D reagents. (This thesis was started…
AI & bio: speakers from Pfizer, Novartis, the Broad, Vertex & @formationbio will discuss some key areas where biopharma industry has been successful in developing & applying AI & giving career advice @thebiotechclub panel on Fri. Link ⬇️ cc @dr_alphalyrae@TechBi0@decodingbio
Welcome to the age of generative genome design!
In 1977, Sanger et al. sequenced the first genome—of phage ΦX174.
Today, led by @samuelhking, we report the first AI-generated genomes. Using ΦX174 as a template, we made novel, high-fitness phages with genome language models. 🧵
Asimov Press party // September 30 // Boston // Asimov HQ
There will be trivia. There will be winners (and losers). And there will be prizes.
Come celebrate, answer questions, and show everyone how much esoteric biology stuff you know. Hope to see you there!
Physical AI acts 🤖
Our general purpose robots use vision language models to flexibly operate your instruments and carry out protocols.
We’re the first company to bring Physical AI to the lab using the same models that power self-driving cars and humanoid robots.
AI is not on track to eradicate disease in our lifetime.
Scientists need to generate more data, but they’re physically limited by how fast they can work.
That’s why we’re launching Medra: Physical AI in the lab, doing and optimizing real experiments.
Thread👇
On the jump forward of CRISPR genome editing beta islet cells, preempting the need for immunosuppression, for a one-shot treatment of autoimmune (Type 1) diabetes
nejm.org/doi/full/10.10…nature.com/articles/d4158…
Large volumes of structured spatial data will help us discover new targets, mechanisms and drugs too difficult to reason about with unaided cognition.
Releasing:
(1) 25M curated cells - the largest open access spatial atlas to date - across 11 major vendors
(2) a tiled AnnData…
We don’t need to simulate the subcellular physico-chemical properties of cells. We need to model biology that will help us cure disease in patients.
That means cell biology in the context of tissues and patients.
Quantum computing could revolutionize phylogenetic inference!
Imagine reconstructing evolutionary histories from massive genomics datasets in minutes, not months.
Quantum algorithms + life's complexity would equal unprecedented insights into biology🧬
Success in academia means becoming a PI and “leaving the bench”
PhDs are trained in this culture. Actual lab work is for junior mentees. Important people don’t do that
So naturally biologists in industry scramble to leave the bench and biotech is bloated with middle managers
432 Followers 3K FollowingTech Leader, thinker, writer, leadership coach. Google I Pinterest I Getty I Omnicom. Expat living in the fast lane. Science and History lover.
322 Followers 1K Following@MIDASUoB PhD student working in clinical bioinformatics. Interested in chronic inflammatory diseases, everything R related and part of @ComunidadCeru Midlands!
294 Followers 2K FollowingEnseñar y comunicar son los nuevos talentos y negocios de la Sociedad del Conocimiento y Aprendizaje
Acumulador de libros sin leer. Biólogo. Aprendiz.
321 Followers 426 FollowingAiming to understand the metabolic side of bacterial infection #immunometabolism #legionella #salmonella #macrophages @institutpasteur
3K Followers 5K FollowingFinal-year PhD building AI to predict molecular toxicity 🤖⚕️💊📈
I discuss AI, economics, investing and geopolitics 📊💱🌍
Views are my own.
4 Followers 64 FollowingLeaving The Lab is a comprehensive and actionable guide that will enable you to transition into new, rewarding careers beyond the laboratory.
715 Followers 2K Followingmusic/ literature/ molecules fan. PhD student at Institute of Chemical Technology, Mumbai. BS-MS (Chemistry) @IISERPune Interested in biomass valorisation.
20K Followers 252 FollowingMentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
3K Followers 3K FollowingCo-founder and Head of Machine Learning @Dyno_Tx. Previously CompBio @Harvard + CS/AI @MIT. Tweets are my own views/interests.
5K Followers 4K FollowingFounder & CEO of Infinita (@InfinitaCity) | Building a longevity bio/acc network city | Based in @ProsperaGlobal | Techno-Optimist | Crypto Cities
357 Followers 419 FollowingCTO at bitBiome Inc. Microbial single-cell genome seq, Big microbe gene DB, Synbio, Biocatalysis and stuff. Tweets are my own.
962 Followers 2K FollowingBuilding the future of healthcare AI platforms @TempusAI. Join our 300+ member NYC Biotech run club https://t.co/5uJBhhgrnf 🇨🇦🇺🇸
4K Followers 3K Followinggroup leader at @CMR_QUT
science. microbiome. content creator for Elsevier, NPG and others!
traveling salesman of second hand ideas
2K Followers 1K FollowingAI/ML, biotech, policy, flying, sometimes in that order | SovAI Unit @SciTechgovuk | PhD @Cambridge_Uni | Prev @benevolent_ai @imperialcollege | Glider Pilot
4K Followers 473 FollowingFollow for AI in Digital Biology and Drug Discovery @NVIDIA, ex Insilico Medicine, ex Yale, PhD UMaryland, views are mine, DM for collabs
41K Followers 2K FollowingDirector of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
2K Followers 869 FollowingHollandbio is de belangenvereniging van biotech bedrijven in Nederland. Samen werken we eraan dat biotech het leven beter maakt!
13K Followers 2K Following“If chaotic good was a biologist” 🧬🦠🧫🌱🥩🌽🦀🐉 exploring and helping wherever biology, technology, and people collide at https://t.co/IJdNoFq1mI