Global Bio x AI Community. A third place for scientists, product managers, computational biologists, engineers and academics working in AI & Software for Biolinktr.ee/techbiotransfo… GlobalJoined August 2024
On the jump forward of CRISPR genome editing beta islet cells, preempting the need for immunosuppression, for a one-shot treatment of autoimmune (Type 1) diabetes
nejm.org/doi/full/10.10…nature.com/articles/d4158…
Large volumes of structured spatial data will help us discover new targets, mechanisms and drugs too difficult to reason about with unaided cognition.
Releasing:
(1) 25M curated cells - the largest open access spatial atlas to date - across 11 major vendors
(2) a tiled AnnData…
We don’t need to simulate the subcellular physico-chemical properties of cells. We need to model biology that will help us cure disease in patients.
That means cell biology in the context of tissues and patients.
Quantum computing could revolutionize phylogenetic inference!
Imagine reconstructing evolutionary histories from massive genomics datasets in minutes, not months.
Quantum algorithms + life's complexity would equal unprecedented insights into biology🧬
Success in academia means becoming a PI and “leaving the bench”
PhDs are trained in this culture. Actual lab work is for junior mentees. Important people don’t do that
So naturally biologists in industry scramble to leave the bench and biotech is bloated with middle managers
I’m helping host an AI x Bio hackathon in San Francisco this weekend with a $5K PRIZE POOL.
We welcome participants from all backgrounds! Brunch + dinner will be provided like wings tonight, surf and turf on Saturday, beef brisket on Sunday, and hamburger sliders on Monday.
Deep Generative Models Design mRNA Sequences with Enhanced Translational Capacity and Stability @ScienceMagazine
1. A groundbreaking study by He Zhang et al. introduces GEMORNA, a deep generative model that leverages Transformer architectures to design mRNA sequences with…
BindCraft is now published in @Nature!
The open-source pipeline for de novo protein binder design achieves significantly improved success rates with nanomolar affinity and therapeutic potential from gene editing to allergens.
Read more at @GENbio:
tinyurl.com/563zepkj
Arc Institute trained their foundation model Evo 2 on DNA from all domains of life. What has it learned about the natural world?
Our new research finds that it represents the tree of life, spanning thousands of species, as a curved manifold in its neuronal activations. (1/8)
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators.
nature.com/articles/s4158…
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out!
Learning Protein-Ligand Binding in Hyperbolic Space
1. HypSeek, a new hyperbolic representation learning framework, improves virtual screening and affinity ranking for drug discovery by embedding ligands, protein pockets, and sequences into Lorentz-model hyperbolic space. It…
After 28 nailbiting days, @arcinstitute's Virtual Cell Challenge has a new leaderboard topper! It took 20 tries, but the Kwisatz Haderach has beaten Snow Leopard and finally brings water to the people
Join now to win the $100,000 top prize!
376 Followers 385 FollowingPhDing in Machine Learning & Neuroscience @ETH Zurich. I also like music quite a bit. Mostly doing stuff for the plot
Moving to BlueSky: @yassinetb.bsky.social
34 Followers 229 FollowingMain aur meri parchayee...
JOAMON🫣Clinical data analyst by profession, passionate towards setting up a palliative care centre, tweets are personal.
20K Followers 250 FollowingMentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
3K Followers 3K FollowingCo-founder and Head of Machine Learning @Dyno_Tx. Previously CompBio @Harvard + CS/AI @MIT. Tweets are my own views/interests.
5K Followers 4K FollowingFounder & CEO of Infinita (@InfinitaCity) | Building a longevity bio/acc network city | Based in @ProsperaGlobal | Techno-Optimist | Crypto Cities
361 Followers 418 FollowingCTO at bitBiome Inc. Microbial single-cell genome seq, Big microbe gene DB, Synbio, Biocatalysis and stuff. Tweets are my own.
953 Followers 2K FollowingBuilding the future of healthcare AI platforms @TempusAI. Join our 250+ member NYC Biotech run club https://t.co/5uJBhhgrnf 🇨🇦🇺🇸
4K Followers 3K Followinggroup leader at @CMR_QUT
science. microbiome. content creator for Elsevier, NPG and others!
traveling salesman of second hand ideas
2K Followers 1K FollowingAI/ML, biotech, policy, flying, sometimes in that order | SovAI Unit @SciTechgovuk | PhD @Cambridge_Uni | Prev @benevolent_ai @imperialcollege | Glider Pilot
4K Followers 461 FollowingFollow for AI in Digital Biology and Drug Discovery @NVIDIA, ex Insilico Medicine, ex Yale, PhD UMaryland, views are mine, DM for collabs
41K Followers 2K FollowingDirector of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
2K Followers 870 FollowingHollandbio is de belangenvereniging van biotech bedrijven in Nederland. Samen werken we eraan dat biotech het leven beter maakt!
12K Followers 2K Following“If chaotic good was a biologist” 🧬🦠🧫🌱🥩🌽🦀🐉 exploring and helping wherever biology, technology, and people collide at https://t.co/IJdNoFq1mI
5K Followers 1K FollowingI was a Synthetic Biologist before it was cool, now working on something new. Previously CSO at Ginkgo Bioworks. @patrickboyle on 🟦☁️