The UnDruggable Series @Undruggable
The Undruggable Series hosts industry-leading forums in TPD, RNA & RAS, translating next generation small molecules to finally drug undruggable targets. hansonwade.com/product/undrug… Joined December 2020-
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Following180
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Today I am going to talk about quality criteria for degrader probes at #TPD23 @Undruggable. Small molecule degraders have great potential as drugs but also as tools to discover novel biology. But quality matters for all such tools. How to assess the quality of degrader probes?
It was a proud moment yesterday when my colleague Marcel Rieker disclosed our #PROxAb shuttle technology at #TPD23 @Undruggable. Along with the poster by Hendrik Schneider they outlined our plug-and-play platform for delivering VHL-based #PROTACs to diseased cells. @merckgroup
Just 2 weeks to go until 600+ TPD experts unite at the 6th Targeted Protein Degradation Summit! (October 30-November 2, 2023) Explore what our 110+ expert speakers will be sharing in the latest 2023 Agenda - ter.li/5ytgrl
We're excited to announce our strategic collaboration with @SeagenGlobal to develop a new class of drugs, Degrader Antibody-Conjugates (DACs). We’ll explore combining 2 approaches to treat cancer: antibody drug conjugation and targeted protein degradation. bit.ly/3L9p1WL
📢 4 weeks to go! Register now for @WorldCDx to secure your spot to hear Genomenon CSO @DrMarkKiel talk with Susanne Rhoades from @LoxoLillyOnc and Tom Defay from @AlexionPharma about evolving approaches for harnessing the genomics of cancer. Info --> ter.li/v1uu7l
100+ TPD experts will share their latest insights at the 6th TPD Summit this October. Explore what they will be presenting here - ter.li/qsmcp2
Join 60+ Proximity Experts at the 3rd Induced Proximity-Based Drug Discovery Summit this July! Explore what our expert speakers will be presenting in the 2023 Agenda - ter.li/2nqwbj
The 6th Targeted Protein Degradation Summit 2023 program has just been released. Explore it here - ter.li/6vf98h
Unite with 80+ experts at the 2nd Hippo Pathway Summit this May 23-25! Explore why they are excited to be joining in the latest 2023 agenda -> ter.li/p0agu5
In under 4 weeks, the 3rd TPD Europe Summit 2023 is coming to London. Hear the latest data from #PhoreMost, #Proteovant, #Novartis & many more exciting companies! View the latest brochure - ter.li/rug4iv
Excited to share Tallas's new computational science in #RNAitherapeutics pre-clinical drug discovery at the 4th Annual #RNAi-Based Therapeutics Summit in Boston, 21-23 March: rnaibased-therapeutics.com/seminar/using-…
Attending the inaugural @Undruggable TPD Assay Development & Screening Summit? Watch Darshan Sappal’s presentation on assay development for optimization of effective #protein degraders. #science
5 Days to Go! Expand Your Assay Capabilities for Next Generation Protein Degraders. Register Online Here - ter.li/jgchot
The 3rd TPD Europe Summit's biggest discount ends this Friday, 18th of November. Explore why you should be securing your place here - ter.li/cy5fly
The Molecular Glue Drug Development Summit arrives this January 24-26, 2023. Register this week & save up to $800! View the agenda to see what's in store - ter.li/ivo7sc
The Targeted Protein Degradation Europe Summit Returns to London on the 28th-30th of March 2023! Check out the brand new agenda here - ter.li/7vcsmr

Ingo Hartung @HartungIngo
16K Followers 782 Following discovery chemistry nerd @Merckgroup; oncology, immunology, targeted protein degradation, ADCs; soccer, politics, tapas can slip into the feed; my own views
Dan Nomura @DanNomura
19K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology; Co-Director of @MTI_UCB
Craig Crews @CraigMCrews
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Jay Bradner, M.D. @jaybradner
23K Followers 906 Following Physician-scientist making medicines with friends, memories with family. EVP R&D at Amgen
Ryan Potts @pottslab
2K Followers 358 Following VP & Head of Induced Proximity Platform, @Amgen | Scientist | Father
Katherine A Donovan @kdonovan1008
2K Followers 340 Following 🇳🇿 Kiwi | Scientist @DanaFarber @harvardmed | Targeted Protein Degradation | Chemoproteomics | Tweets are my own | find me on🦋
Radek Nowak @RPNowak
2K Followers 736 Following Professor @UniBonn. Former @DanaFarber @harvardmed | Targeted Protein Degradation | Chemical and Structural Biology | @UniofOxford alumni. Tweets are my own.
Thomä Lab @LabThoma
2K Followers 346 Following We are a structural biology lab located both at EPFL in Lausanne and at the Friedrich Miescher Institute in Basel.
Varun Shah @shahvarun28
365 Followers 412 Following Scientist @Dikiclab @ibc2_gu @proxidrugs | Passion for cancer research and Targeted Protein Degradation
Milka Kostić, PhD @MilkaKostic
4K Followers 3K Following Director of @DFCI_ChemBio pursuing innovation, translation & transformation through #chemicalbiology. Opinions and views strictly my own!
Danette Daniels @danetteldaniels
1K Followers 609 Following Scientist, biophysics, cell biology, targeted protein degradation, and drug discovery. Adventure athlete, runner, and mountain biker | Opinions are my own
Kanak Raina @rainakanak
280 Followers 372 Following VP @ Biotech Newco. Ex-Halda Tx; Arvinas. Drug Discovery. Induced Proximity Therapeutics. Opinions my own.
Luke Simpson @lukemsimpson
1K Followers 1K Following Product Support Investigator at Abbott Rapid Diagnostics Dundee | previously @UoDCeTPD PROTAC Cell Biologist & @mrcppu @sapkota_mrcppu PhD
J. Am. Chem. Soc. @J_A_C_S
185K Followers 10K Following Research, news, and information from the Journal of the American Chemical Society.
Mikołaj Słabicki @biomiko
1K Followers 480 Following Assistant Professor at MGH Krantz Family Center for Cancer Research, Harvard Medical School, Broad Institute of MIT and Harvard.
Cris Mayor-Ruiz @CrisMayorRuiz
3K Followers 995 Following Passionate scientist, runner, basket. Group leader at @IRBBarcelona | Targeted protein degradation | Chemical biology | Postdoc @CeMM_News, PhD @CNIOStopCancer
Narkhyun Bae @ghostbnh
523 Followers 1K Following TPD Drug Discovery Group Leader at Daewoong Pharmaceutical Co.,Ltd./Biochemist&Chemical Biologist
Pengyu Yang @Pengyu19
841 Followers 659 Following Ph.D., Drug Hunter @RayThera | @PlexiumTx | @scrippsresearch alum | #discoverychemistry | #medchem #proteindegradation
叢雲くすり (創�... @souyakuchan
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Gunning Group @GunningLabUofT
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Kokedama @Kokedama_camp
1 Followers 51 Following
OncoDaily IO @OncoDailyIO
2K Followers 7K Following Your daily source for the latest updates, insights, and news in immuno-oncology. #OncoDailyIO #OncoDaily #immunooncology #immuneoncology #immunotherapy
Max Brodermann @MaxBrodermann
9 Followers 72 Following
Wes Yanowitch @wesyano
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Rizana Azees @azees66543
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Majd Hijjawi @Majdhijjawi224
22 Followers 385 Following 👩🏻🔬 Researcher in pharmacology 🧬 and drug design 💊
MSAID @msaid_de
464 Followers 459 Following MSAID transforms the way scientists analyze proteomics data ➡️ Request a Free CHIMERYS Demo: https://t.co/wglgKtuQDd Follow us: https://t.co/E6DFmrbTAL
PJ @Jungster37
106 Followers 589 Following Words have meaning. Truth is real. Honesty matters. Kindness is important. Opinions my own. Not responsible for egregious puns.
jujbhn @sWXkaZY99g40093
0 Followers 41 Following
Lokesh Gakhar @LokeshGakhar
210 Followers 495 Following Drug Discovery | Targeted Protein Degradation | Structural Biology | Protein Science | Biophysics | Interfacial Phenomena | Automation
Abdullah Al Noman @Noman_abdullah
129 Followers 246 Following Interested in Science, Politics, and everything else.
Saikat Chowdhury @saikatbib
108 Followers 454 Following Postdoc Fellow at MD Anderson Cancer Center | Review editors @FrontCellDevBio & @FrontBioinf | Alma mater @csir_ncl & @CalcuttaUniv | Computational Biologist
Biswanath Shaw @Bis_acrylamide
306 Followers 2K Following Exploring Biophysics @Cornell | Curious about Finance & Businesses | Love 🚴, podcasts & Audiobooks | IISc UG | HSMS | iGEMer
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0 Followers 50 Following
Ben Reisman MD PhD @BenjaminReisman
1K Followers 3K Following Onc Fellow @Hopkins_HemOnc via @OslerResidency + @VanderbiltMSTP • chemical biologist ⚗️
Michael @brigendcelt
20 Followers 330 Following
Rohan Rej @rohanrej
1 Followers 47 Following
Tetsuya Iida @tetsuii
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Greg Findlay @gregfindlaylab
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Mass Dynamics @massDynamicsCo
851 Followers 2K Following Collaboration software to unleash proteomics. Delivering high-confidence analysis - in one place - so scientists can free humanity from the burden of disease.
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jsf5 @jsf5
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张changfa @changfa166491
0 Followers 23 Following
Vanessa Buffa @ChemVane93
1 Followers 5 Following
Vusumuzi Ngonidzashe ... @VusaHove
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GGGddd @GGGddd377918
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Balmiki Kumar @BKumarUTM24
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喵喵喵 @2053380994qqco1
27 Followers 180 Following 永远17岁/ 在英留学党 /肥宅/ 日本語勉强中 / ACG / moe / 价值观质疑中 / 自我厌恶 / 业余画画 / 理科 /化学bsc/人生目标是混吃等死/如果有回fo会很感动/日常推/喜欢性格可爱的人/INTJ
Andy @_targetability_
6 Followers 67 Following
Salomé Llabrés Prat @s_llabres
127 Followers 977 Following
Hontrue @Hontrue1
28 Followers 650 Following
Caleb Heaslip @CalebHeaslip
21 Followers 471 Following
Tunoko @tunoko_tunoko
500 Followers 1K Following
Kavita Tiwari @kaveetatiwari
192 Followers 177 Following Senior Project Scientist - Early Discovery. Writer/Poet. An ardent learner. Loves challenges. A Total Rebel.
ぐるー @molecular_gluer
10 Followers 167 Following Chemical biologist, drug discovery, induced proximity
Harry Taylor @Harryyyyt
160 Followers 557 Following Post-Doc-ing at the University of Nottingham 👨🏻🔬 Studying Structural Biology via Protein Footprinting #TeamMassSpec
Kyle Boulanger @KyleBoulanger22
454 Followers 632 Following
Peter Meinke @PeterTMeinke
15 Followers 144 Following
Haseeb @Abdulhaseeb_k
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Bin Mao @Bin_RUG
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Diana M. Soto M. @soto_marcela89
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Ingo Hartung @HartungIngo
16K Followers 782 Following discovery chemistry nerd @Merckgroup; oncology, immunology, targeted protein degradation, ADCs; soccer, politics, tapas can slip into the feed; my own views
Guillaume Laconde @Glaconde34
5K Followers 110 Following Medicinal chemist, PROTAC and #TPD technology OXELTIS Scientist, https://t.co/F8c4eERuOA Communication Deputy for the SCT, https://t.co/8j34whJXIQ Tweets = my own.
Keith Hornberger @KRHornberger
12K Followers 260 Following TPD-med chem-hiking-cocktails / while I have a connection to Arvinas, all opinions expressed are mine and do not represent the views or positions of the company
Dan Nomura @DanNomura
19K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology; Co-Director of @MTI_UCB
Craig Crews @CraigMCrews
9K Followers 948 Following Yale Professor, Founder of @ArvinasInc, Halda Therapeutics, https://t.co/YoR6Yo3d3u, @[email protected]
Darryl B McConnell @D_B_McConnell
8K Followers 373 Following drug discoverer, medicinal chemist, wannaberunner, wannabeartist, builder of ponds and webmaster
Jay Bradner, M.D. @jaybradner
23K Followers 906 Following Physician-scientist making medicines with friends, memories with family. EVP R&D at Amgen
Ryan Potts @pottslab
2K Followers 358 Following VP & Head of Induced Proximity Platform, @Amgen | Scientist | Father
Rapé Lab @RapeLab
4K Followers 119 Following molecular mechanisms of cell fate specification in development and disease; molecular glues and induced protein degradation as new therapeutic options
Alessio Ciulli @alessiociulli
6K Followers 392 Following Prof @Dundeeuni. Founder and Director @UoDCeTPD. Founder @AmphistaThera. We develop molecules that induce protein interactions and degradation
Katherine A Donovan @kdonovan1008
2K Followers 340 Following 🇳🇿 Kiwi | Scientist @DanaFarber @harvardmed | Targeted Protein Degradation | Chemoproteomics | Tweets are my own | find me on🦋
Ivan Đikić @iDikic2
9K Followers 948 Following Scientist @goetheuni, Professor @IBC2_GU, Fellow @MPIBP. Interests in research, education, science popularisation & snowboarding🙃
Radek Nowak @RPNowak
2K Followers 736 Following Professor @UniBonn. Former @DanaFarber @harvardmed | Targeted Protein Degradation | Chemical and Structural Biology | @UniofOxford alumni. Tweets are my own.
Thomä Lab @LabThoma
2K Followers 346 Following We are a structural biology lab located both at EPFL in Lausanne and at the Friedrich Miescher Institute in Basel.
Stuart Schreiber @SchreiberStuart
12K Followers 374 Following Truth-seeking scientist; equal parts Cajun, Mississippian, Irish, Hungarian.
Milka Kostić, PhD @MilkaKostic
4K Followers 3K Following Director of @DFCI_ChemBio pursuing innovation, translation & transformation through #chemicalbiology. Opinions and views strictly my own!
Danette Daniels @danetteldaniels
1K Followers 609 Following Scientist, biophysics, cell biology, targeted protein degradation, and drug discovery. Adventure athlete, runner, and mountain biker | Opinions are my own
Fischer Lab @fischerlab1
2K Followers 54 Following News and updates from the Eric Fischer Lab, Est. Oct 2015 @DanaFarber @harvardmed | E3 Ligases | Ubiquitin | Degraders | Chemical Biology | Cancer
Matt Disney @disney_lab
6K Followers 1K Following Walker of the earth RNA & Chemical Biology practitioner @J_A_C_S associate editor
Luke Simpson @lukemsimpson
1K Followers 1K Following Product Support Investigator at Abbott Rapid Diagnostics Dundee | previously @UoDCeTPD PROTAC Cell Biologist & @mrcppu @sapkota_mrcppu PhD
Women in TPD & Induce... @WomenInTPD
524 Followers 200 Following
Justine Koenigsberg @jkoenigsberg
44 Followers 118 Following Head of Investor Relations at Kymera Therapeutics (NASDAQ: KYMR)
Jim Wells @realJimWells
2K Followers 130 Following @UCSF professor interested in antibody engineering and how cells remodel their extracellular proteome in health and disease
Hanson Wade @HansonWade
352 Followers 10 Following We put on events all over the world, giving people clarity on their jobs and industries. We build careers, help companies and highlight progress
Amphista Therapeutics @AmphistaThera
551 Followers 30 Following A global leader in the discovery and development of next generation targeted protein degradation therapeutics with the potential to treat a range of diseases.
John Castle @joccastle
802 Followers 1K Following Inventing & translating technologies for therapies. ML AI ‘omics & comp biology. Molecular glue for targeted protein degraders. @MonteRosaTx Tweets my own
Vesna Vetma @VesnaVetma
367 Followers 195 Following Senior Cell Biologist at CeTPD, Dundee| Aerialist
Targeted Oncology @TargetedOnc
21K Followers 4K Following Oncology news and insights from leading researchers and cancer centers.
OncLive.com @OncLive
48K Followers 2K Following Healthcare publisher of oncology focused articles, videos, panel discussions, and much more that run the gamut of oncology care and management.
World Bispecific Foru... @Bispecific
518 Followers 520 Following Scientist interested in bispecific antibodies: Keen to discuss developments, challenges and new technologies
Nurix Therapeutics @Nurix_Tx
643 Followers 4 Following Nurix is writing medicine’s next chapter using targeted protein degradation as a new script to outmatch disease. $NRIX
Dr. Janet Woodcock @DrWoodcockFDA
14K Followers 65 Following Former Principal Deputy Commissioner at @US_FDA. This account is now archived.
PROXIDRUGS @proxidrugs
598 Followers 103 Following PROXIDRUGS Cluster4Future is no longer actively using this account. We invite you to continue engaging with us on LinkedIn and Bluesky.
neomorphinc @neomorphinc
279 Followers 2 Following Solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets’.
Eric Wang @eswang01
73 Followers 25 Following Assistant Professor @SBPDiscovery @SBPCancerCenter | Chemical Biology | Views my own
Laurent Audoly @laurentaudoly
256 Followers 215 Following CEO of Kymera. Taking out the undruggable world one target a time. Board member American Skin Association. Living proof of the 3 L.
Matthieu Schapira @mattschap
1K Followers 116 Following Structural/computational chemistry - CACHE challenges - @mattschap.bsky.social
Nello Mainolfi @NelloMainolfi
2K Followers 287 Following Founder, President & CEO @kymeratx - $KYMR - runner and sailing enthusiast - tweets my own
Behnam Nabet @behnamnabet
1K Followers 536 Following Assistant Professor @fredhutch | dTAG designer | Proud Husband & Baba | He/Him/His
Michal Walczak @MichalWalczak7
24 Followers 37 Following Captor Therapeutics (CSO) | Chemical biology | Biophysics | Structural biology | Protein NMR
Harald Weinstabl @ChemHaWei
134 Followers 102 Following Innovator, Challenger, all opinions and tweets are personal and not influenced by or towards my employer
Giovanni Nigita, PhD @GianniNigita
146 Followers 385 Following Assistant Professor @OhioStateMedOnc, @OhioStateMed @OSUCCC_James. #CancerInformatics, #ncRNAs, #Epitranscriptomics, #HERVs, #LungCancer,#LiquidBiopsy, #ML, #AI
Philips Healthcare @PhilipsHealth
67K Followers 90 Following Better care for more people 💙. Tweet @PhilipsCare for product questions. Read our House Rules: https://t.co/JvWhcAz2as
Oncotarget @Oncotarget
3K Followers 4K Following Oncotarget is a peer-reviewed, open-access biomedical journal indexed in MEDLINE, PubMed, PMC, Scopus, and more.
Rune Busk Damgaard @rbdamgaard
2K Followers 1K Following Associate Professor, Section for Medical Biotechnology, Technical University of Denmark. Studies ubiquitin signalling in inflammation, metabolism, and disease.
Satpal Virdee @SatpalVirdee
602 Followers 192 Following Professor of Chemical Biology, MRC Protein Phosphorylation and Ubiquitylation Unit
Adam Fletcher @E3ligase
620 Followers 655 Following New recruit at @CVRinfo, asking how cells deal with nasty viruses #UKRIFLF
Juraj Ahel @JurajAhel
155 Followers 203 Following
T&F Bioscience @tandfbiosci
3K Followers 2K Following An international publisher covering Biological and Life Sciences
MRC-Uni of Glasgow Ce... @CVRinfo
7K Followers 1K Following Fascinated by viruses and the diseases they cause. @The_MRC @UofGlasgow
Roivant Sciences @Roivant
2K Followers 122 Following Roivant aims to improve the lives of patients by accelerating the development and commercialization of medicines that matter
Dana-Farber @DanaFarber
112K Followers 9K Following Dana-Farber Cancer Institute - a leading center for expert, compassionate cancer care and advanced research. Appts: 877-442-3324 | https://t.co/HvCwkLltic
bioRxiv @biorxivpreprint
137K Followers 23 Following Daily summaries of preprints posted in each bioRxiv Subject Area. Find ways to get social media alerts to individual papers at https://t.co/wrlEW1phDV
bioRxiv Biophysics @biorxiv_biophys
5K Followers 0 Following
FDA Drug Information @FDA_Drug_Info
341K Followers 59 Following Receive the latest drug information from the US FDA. Contact us at 1.855.543.3784 or [email protected]. Privacy Policy - https://t.co/K2nAJlm94m.
Johnson & Johnson @JNJNews
245K Followers 157 Following Follow us to see how we're solving the world's toughest health challenges. Community Guidelines: https://t.co/XOPIzkbgzo
Roche @Roche
241K Followers 220 Following We advance science so that we all have more time with the people we love. Read our community guidelines: https://t.co/7k1HdbdrYL
EFPIA @EFPIA
25K Followers 4K Following EFPIA is the voice of the research-based pharmaceutical industry in Europe #WeWontRest #TeamVaccines https://t.co/y1FLniUcoT
STAT @statnews
160K Followers 5K Following Reporting from the frontiers of health & medicine. Sign up for any of our 10 free newsletters here: https://t.co/CBx3GZBv31
Bloomberg @business
9.8M Followers 104 Following The first word in business news. Singapore newsletter: https://t.co/RtyaUOdLdF Newsletters: https://t.co/nWaCxHSKuU Podcasts: https://t.co/096e9xMbPz
Astellas Pharma CA @AstellasCA
576 Followers 499 Following A pharma company dedicated to changing tomorrow by improving the health of people around the world. Tweets intended for a Canadian audience.
Astellas Pharma US @AstellasUS
51K Followers 1K Following A pharma company dedicated to changing tomorrow by improving the health of people around the world. Tweets for U.S. audience. Guidelines: https://t.co/AJlgiDgWSG
Boehringer Ingelheim @Boehringer
104K Followers 3K Following Science for a healthier tomorrow. Medical innovation for people and animals. #LifeForward Community Guidelines: https://t.co/d5aGI1ZS8e
BridGene Biosciences,... @BridgeneI
5 Followers 0 Following BridGene is a biotechnology company focused on discovering and developing innovative small molecules that drug high-value but previously undruggable targets.
Neumora @NeumoraTx
745 Followers 62 Following At Neumora, we are focused on conquering one of the greatest medical challenges of our generation: the global brain disease crisis.
Sage Therapeutics @SageBiotech
3K Followers 413 Following Our mission is to pioneer solutions to deliver life-changing brain health medicines, so every person can thrive. Community Guidelines: https://t.co/O3kvO0DUOA