Anand K @Y_anandk
Senior Scientist @Sanofi Postdoc @iecb_bordeaux, PhD @institutpasteur #CryoEM #MembraneProtein #DrugDiscovery #Beerlover mypcscan.blogspot.com Paris, Ile-de-France Joined December 2010-
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Cryo-EM in drug development!
Protein structure determination is forging the way for the discovery of diverse biologic and small molecule therapies. @sanofi recently joined @endpts & @thermofisher to discuss how they use #cryoEM to advance #DrugDiscovery. Watch now on-demand: ter.li/1ilyck
What do breaking world records and making breakthrough drug discoveries have in common? Find out how scientists and athletes are #IgnitingPotential with #TeamSanofi @TeamEzra05 🔥.
Register for a exciting webinar on "Cryo-electron Microscopy: Revolutionizing Rational Drug Discovery Pipelines" webinars.endpts.com/cryo-electron-…
PostDoc, Senior Scientist and/or PhD position in Cryo-EM Method Development in Lausanne We are looking for a PhD student, PostDoc, or Senior Scientist to join our team to support cryo-EM data collection, using conventional and novel approaches, including diffractive imaging.
Come and join my team as a cryo-EM scientist. Its a great opportunity to apply your cryo-EM skills and aquire new ones in the field of drug discovery. sanofi.wd3.myworkdayjobs.com/SanofiCareers/…
Very excited to share our last paper done at @DBSC_IP and publish in @pnas. We use integrative structural biology to challenge the paradigm of an universally conserved architecture in PDH metabolic complexes pnas.org/content/118/48… #cryoEM #tuberculosis #actinobacteria
Structural and biophysical work by Nicolas Reyes lab @iecb_bordeaux defines the ion-coupling mechanism of #synaptic #glutamate transport via human excitatory amino acid transporter #EAAT1 embopress.org/doi/10.15252/e…
This week in Nature: Protein misfolds – Neurodegenerative diseases classified by shapes of tau filaments. Browse the issue here: go.nature.com/3mKuu9E
CD20 is the target of therapeutic #antibodies used in #cancer #immunotherapy. Here, CD20 solved in complex with Rituximab Fab by Reyes Lab @institutpasteur, published on @ScienceMagazine PDBid 6y90 #sciart #proteinimaging #antibody
Scientists in France have elucidated the binding mechanisms of monoclonal antibodies used in cancer immunotherapy, aiding in the rational design of future therapeutics. #structuralbiology #cryoem ow.ly/Xe9S50B1ID8
❓ Comment agissent les #anticorps thérapeutiques ? Pour la 1ère fois, des chercheurs ont obtenu des images de l’interaction entre certains anticorps et leurs molécules cibles, au niveau de l’atome. @CNRS @institutpasteur @univbordeaux pasteur.fr/fr/espace-pres…
#ImmunoTherapeutics | Binding mechanisms of therapeutic antibodies to human CD20 | CryoEM & Structure of CD20 in complex with type II FabOBZ | Nicolas Reyes @institpasteur @ScienceMagazine buff.ly/3kJQfoa
Binding mechanisms of therapeutic antibodies to human CD20. dlvr.it/RdhgKB
#Communiqué 🗞️ | Pour la première fois, des scientifiques du @CNRS, de l’@institutpasteur et de l’@univbordeaux ont observé l’interaction entre les anticorps thérapeutiques et leur protéine cible. #Immunothérapie ➡️ cnrs.fr/fr/immunothera… 📙 science.sciencemag.org/cgi/doi/10.112…
Thrilled to see our long lasting collaborative effort with the great Nicolas Reyes's lab @CNRS @univbordeaux @institutpasteur on #CD20 #therapeutic #antibodies published in the last issue @ScienceMagazine !!!! science.sciencemag.org/content/369/65…
Thank you @fronzes_lab, without your contribution and access to @EArctica it wouldn’t have been possible! :):) congratulations to you as well!
@iecb_bordeaux scientists reveal the structure of therapeutic Fabs used in cancer immunotherapy bound to their human target. @CNRSAquitaine @univbordeaux Published in @ScienceMagazine science.sciencemag.org/content/369/65…
Our Cryoem structures of CD20 in complex with Type-I (human as well as a rodent) and Type-II reveal the mechanistic differences #CryoEM #CD20 #structure science.sciencemag.org/content/369/65… cnrs.fr/en/behaviour-t…

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