Aishwarya Prakash @_AishPrakash
PhD scholar @JNCASR trying to understand the origin of blood stem cells in mammals| Hematopoiesis, Mitochondria, Embryos | Zoologist from @hrcduofficial | Bengaluru, India Joined June 2023-
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Mitochondrial-activity-driven hematopoietic stem cell fate and lineage choice is first established in the aorta-gonad-mesonephros dlvr.it/TND8v6
Excited to share that a major part of my PhD work is out now in @CellReports!! We show that mitochondria shape blood stem cell formation and function during embryogenesis, setting the stage for healthy blood production throughout life. @InamdarManeesha cell.com/cell-reports/f…
Bend it like Bendless!! We are on the Rxiv @biorxivpreprint this month with our new story on the role of K63 ubiquitination in regulating signalling during hematopoiesis! Congrats team 👏🎉 Wish us luck :) @biopatrika @VoicesofIndAcad biorxiv.org/content/10.110…
Now out in the July 10th issue of @CellCellPress LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs: Cell cell.com/cell/fulltext/…
Officially Dr. Prathamesh Dongre! 🎓✨ Thrilled to share that I have completed my PhD in Cellular and Molecular Biology from @jncasr. Huge thanks to my family, friends, and lab members for unwavering support! 🧪 🔬 Onto the next one! ❤️
Online now: Eomes directs the formation of spatially and functionally diverse extraembryonic hematovascular tissues dlvr.it/TLXNzc
Happy to share our work led by @Kishalay_ish & Rohit where we show how localized & systemic genetic modulation of cellular ageing can impact organ homeostasis. Accepted version out now! @Co_Biologists journals.biologists.com/bio/article/do… @biopatrika @VoicesofIndAcad
Delighted to share our recent study now out @embojournal; embopress.org/doi/full/10.10…. We characterized the hematopoietic niche in adult spleen, a lesser known host for hematopoietic stem cells.
It brings us great joy to share that our PhD student, Mr. Yash Acharya, has been selected for the prestigious ASM Future Leaders Mentorship Fellowship (FLMP) by @ASMicrobiology Congratulations @yash_amr @NCU_JNCASR @jncasr #ASM #FLMP #AMR
Excited to share our latest publication in @eLife: Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development doi.org/10.7554/eLife.… Huge thanks to all the amazing co-authors @InamdarManeesha @PreetiJ89839688 and Ronak 🙂
How does metabolism act through generic chromatin modifiers promote specific cellular states? Simultaneous modification of transcription factors and chromatin, enhancing epigenetic signal to noise ratios. embopress.org/doi/full/10.10…
🚨 New review out! 🚨 With my amazing PhD student @lydia_pouncey we dive into how the chick embryo has helped shape our understanding of developmental haematopoiesis and the technologies to tackle fundamental questions🩸🧬 Read it here 👇 🔗 bit.ly/4jLMn3O
Excited to share my co-first author paper from Sunil Laxman's lab, now out in PNAS @PNASNews on mitochondrial activity independent regulation of mito-morphology via ROS. Great working with Gaurav, Aayushee & @a_swagata #Mitochondria #Metabolism #Redox pnas.org/doi/10.1073/pn…
1. My postdoctoral work on the non-canonical role of an autophagy-related protein at the spindle pole body (SPB) is now out in @PLOSBiology (doi.org/10.1371/journa…).
Exciting progress in Alzheimer’s research! 🧠 Prof. Maneesha Inamdar’s lab at BRIC-inStem is advancing studies on Asrij/OCIAD1 to reduce neuroinflammation and improve brain health. Congratulation! @DBTIndia @DBT_inStem
Our article published in Journal of Neuroinflammation! 😁 Asrij promotes microglia-mediated neuroinflammation in Alzheimer’s disease @InamdarManeesha @govindaraju_tgr @jncasr @DBT_inStem link.springer.com/article/10.118…
New Paper Alert! Prof. Maneesha Inamdar’s lab @BRIC_inStem investigates the role of microglia in Alzheimer's disease, shedding light on the function of Asrij/OCIAD1 in neuroinflammation. Read more here: biorxiv.org/content/10.110… Advancing neuroscience, one discovery at a time!…
How blood ages - A curious case of mice and men. Our latest study @Nature published today. Biological processes such as DNA mutagenesis often scale to animal time. Blood stem cells have special evolutionary protection against this. 👉🏽nature.com/articles/s4158…
🚨Excited to share that our manuscript "Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing" W/ @RafiiShahin and the Twitter/X'less CompWiz Sean Houghton is out @NatImmunol 👇🏽👇🏽👇🏽 🧵 nature.com/articles/s4159…
🔥New Fraticelli lab publication🔥 “Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemia driver mutations” Two new figures compared to the pre-print, with more in vivo and sequential mutagenesis data. sciencedirect.com/science/articl…
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