So Yeon Koo @_SoyeonKoo

neurobiologist post-doc in the world of RNA Dr. V. Narry Kim lab @ibs_media @SeoulNatlUni scholar.google.com/citations?user… Seoul Joined February 2020

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101
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Lorenz @studerl

a year ago

How to trigger age-related features in hPSC neurons? In a CRISPR screen @NatSaurat identified neddylation inhibition as a tool to trigger hallmarks of aging in neurons and selective degeneration in AD or PD but not isogenic control neurons. @CellStemCell bit.ly/3XBxCsA

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Cell @CellCellPress

a year ago

Now online! TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons dlvr.it/T8DDc6

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Lorenz @studerl

a year ago

Excellent thread from @_SoyeonKoo on the paper (and also her thesis work 😊). Congrats!

So Yeon Koo @_SoyeonKoo

a year ago

Excellent thread from @_SoyeonKoo on the paper (and also her thesis work 😊). Congrats!

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Noopur Khobrekar @NoopurKhobrekar

a year ago

Amazing work from an outstanding scientist @_SoyeonKoo (that I greatly admired in the Studer lab)! Many Congrats on this well-deserved achievement.

So Yeon Koo @_SoyeonKoo

a year ago

Amazing work from an outstanding scientist @_SoyeonKoo (that I greatly admired in the Studer lab)! Many Congrats on this well-deserved achievement.

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Waggoner Lab @LabWaggoner

a year ago

@CellCellPress @TaeWanKim0 @studerl Transient TNF-α inhibition overcomes a p53-dependent survival restriction in grafted dopamine neurons as a clinically relevant strategy to promote functional dopamine neuronal engraftment in Parkinson’s disease cell.com/cell/abstract/…

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Lorenz @studerl

2 years ago

“Why human brain cells grow so slowly?” This is a video piece on our epigenetic barrier paper at @NatureVideoChannel on @YouTube. youtube.com/watch?v=lIJkc6…

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Gabriele Ciceri @gabriele_ciceri

2 years ago

Excited to share that our paper on an epigenetic barrier setting timing of maturation in human neurons is finally out @Nature! go.nature.com/48dhO0V.

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Lorenz @studerl

2 years ago

The GENtoniK paper is finally out in Nat Biotech! go.nature.com/3ROgdZf A chemical cocktail to drive maturation of neurons and other hPSC-derived cell types. Congrats to Emiliano, Andrew, @OberstPolina, @YZorina, @BaggioliniA, @ChenShuibing @gabriele_ciceri and many others.

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Lorenz @studerl

2 years ago

Preprint led by @chaozhangw @NatSaurat @dbetel on a strategy for measuring/manipulating cellular age bit.ly/3KIJ7XI. “RNAge” is used to track induced aging strategies in iPSC human neurons & to perform in silico screen for identifying novel aging & rejuvenation compounds

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Lorenz @studerl

2 years ago

Excited to share initial press release @BlueRockTx on promising results of Phase 1 trial in 12 PD patients bit.ly/3JCKneG. A major milestone on a 20+ year journey. Amazing leadership by @TabarViviane, @MSKCancerCenter & @BlueRockTx (@bigosi, Mark Tomishima & many more).

Viviane Tabar @TabarViviane

2 years ago

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The Science of Parkinson's @ScienceofPD

3 years ago

Interesting @biorxivpreprint from @studerl & colleagues using in vivo CRISPR-Cas9 screen to identify p53-mediated apoptotic cell death as major contributor to dopamine neuron loss & uncovered a causal link of TNFa-NFκB signaling in limiting cell survival biorxiv.org/content/10.110…