Yichen Wang @_YichenWang_
Postdoc @Sangerinstitute @Cambridge_Uni. Somatic evolution of normal aging/pre-cancer. BS bio&math @PKU1898 sanger.ac.uk/person/wang-yi… United Kingdom Joined January 2021-
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🚨 We’re #hiring a Staff Scientist to drive innovative computational workflows for large-scale, multi-omics data in human microbiome research @LawleyLab @sangerinstitute 📅 Closing date: 27th April 2025 📢 Please share & apply! sanger.wd103.myworkdayjobs.com/en-US/Wellcome…
The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our Nature paper: nature.com/articles/s4158…
We trained a genomic language model on all observed evolution, which we are calling Evo 2. The model achieves an unprecedented breadth in capabilities, enabling prediction and design tasks from molecular to genome scale and across all three domains of life.
I’ve opened two more positions in my lab for both junior and senior RAs—no PhD required. 🌟 Spread the word! 🔬 Dry Lab: aprecruit.ucsf.edu/JPF05334 💧 Wet Lab: aprecruit.ucsf.edu/JPF05332 Thanks for sharing!
Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!
Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]
Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]
🚨𝐇𝐞 𝐋𝐚𝐛 job opportunity @UCSF 🚨: I'm hiring TWO postdocs - an experimentalist and a computational biologist. Join us to use cutting-edge single-cell and spatial technologies to unravel the mysteries of human tissues. opportunities.ucsf.edu/content/open-p…
Genetic variation across and within individuals go.nature.com/3PFrsTf #Review by @ZhiYu_ACGT, @TimCoorens, Md Mesbah Uddin, Kristin G. Ardlie, @nialljlennon & @pnatarajanmd
Very excited to share our latest preprint on somatic mutations in the normal stomach. We found many surprises, incl. hypermutant glands, recurrent somatic trisomies and a unique landscape of driver mutations. Thread below! biorxiv.org/content/10.110…
Excited to share iStar, which was just published in @NatureBiotech By leveraging high-resolution histology image information, iStar can increase the spatial resolution of sequencing-based ST platform such as Visium @10xGenomics to near single-cell level.
Excited to share iStar, which was just published in @NatureBiotech By leveraging high-resolution histology image information, iStar can increase the spatial resolution of sequencing-based ST platform such as Visium @10xGenomics to near single-cell level.
🔬My sc/spatial genomics lab (Launch at #Stanford on Dec. 16) is seeking experimental RAs & post-docs in genomics & dev bio. Come to work with me and a vibrant team of sys biologists, ML experts, etc. to push the boundaries of gene regulation of development & disease. #HiringNow
excited to announce our new paper in @CellCellPress on ARC-well by @KaileWang @TapsiKS, on a new single cell DNA-seq nanowell method that we applied to study DCIS and recurrences, revealing an evolutionary bottleneck during progression @MDAndersonNews sciencedirect.com/science/articl…
Very excited to see our study on a case of ALL to AML switch after CAR-T treatment out in @NatureCancer! Using deep genome sequencing, we show the cancer switched cell types to escape therapy. @broadinstitute @sangerinstitute @getz_lab Thread below 🧵 nature.com/articles/s4301…
Two exciting method papers in @NatureGenet by Olivier Delaneau and team reporting * A new tool (GLIMPSE2) to impute genetic variants accurately from low-coverage sequencing data * A new tool (SHAPEIT5) to phase rare variants to identify compound heterozygotes My favourite is…
Two exciting method papers in @NatureGenet by Olivier Delaneau and team reporting * A new tool (GLIMPSE2) to impute genetic variants accurately from low-coverage sequencing data * A new tool (SHAPEIT5) to phase rare variants to identify compound heterozygotes My favourite is… https://t.co/8GFGpXbDXr
Posting my short talk earlier today on Cancer Mutational Signatures for a joint NIEHS-NCI workshop lectures.gersteinlab.org/summary/Though…
Didn’t know about this episode. Must watch it. The whole human genome sequence would require way more pages. From start to end it would fill a whole shelve with 30 books, see wellcomecollection.org/articles/WcvK4…
Didn’t know about this episode. Must watch it. The whole human genome sequence would require way more pages. From start to end it would fill a whole shelve with 30 books, see wellcomecollection.org/articles/WcvK4…
June really appears to be my lucky month - our new preprint is out on @researchsquare! 😍 Together with @doctor_msc, @andrewrjlawson and many others we looked into the life history of mitochondria in the human haematopoietic system researchsquare.com/article/rs-308…. [1/x]
Big congrats to the rising star! So well-deserved.
Big congrats to the rising star! So well-deserved.
Ruxandra Teslo 🧬 @RuxandraTeslo
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Inigo Martincorena @imartincorena
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Ran Zhou @xRan_Chou
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Jingzhan @JingzhanLu
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Wave Ye @yewaveye
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Oded Rechavi @OdedRechavi
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Fabian Theis @fabian_theis
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Ming "Tommy" Tang @tangming2005
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Tom Mitchell @Tom_J_Mitchell
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Anshul Kundaje (anshu... @anshulkundaje
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Cambridge University @Cambridge_Uni
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Wellcome Sanger Insti... @sangerinstitute
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David Adams @David_J_Adams
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bioRxiv @biorxivpreprint
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School of Biological ... @Cambridge_SBS
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CambridgeEpigenetics @EpigeneticsClub
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Zhenyu Liu @_LiuZhenyu
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roser @roserventotormo
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