Anand Singh @anandkamalsingh
Resurgent Houston, TX Joined September 2009-
Tweets109
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HowCouldtheEpigenomeUnlock InsightsintoOnco-Immunologyfor BetterImmunotherapy?I’m excited to share our new study in STM.Special thanks @raikunal, @ManrongW, @Bijender2050, @lab_rezvani and @may_daher. Curious to learn more?science.org/doi/10.1126/sc… #Teamwork #RAILAB #METI
We are happy to release these new human reference single-cell maps for #ProjecTILs
Happy to share our Review on chromatin state dynamics and computational tools to explore differential CS in normal vs. cancer cell | @ Briefings in Bioinformatics | w/ @aayushraman | academic.oup.com/bib/advance-ar… | @PMResearch_UHN @broadinstitute @MDAndersonNews #epigenomics #chromatin
Ever wonder how Transcription Factors work as a team? Thrilled to share our latest work on TF cooperativity now online @MolecularCell “Stripe” TFs provide accessibility to regulatory DNA in mammalian genomes cell.com/molecular-cell… What are stripe TFs, you ask? 🧵👇 1/13
Analysis of #scRNAseq requires constant, tedious, interaction with genomics databases. To facilitate querying from @ensembl et al., @NeuroLuebbert developed gget: biorxiv.org/content/10.110… (code @ github.com/pachterlab/gget). gget has many uses; a 🧵on the its amazing versatility: 1/
Our new preprint, led by @YUHANHAO2, introduces bridge integration: cross-modality alignment via a multiomic 'bridge' dataset. We map single-cell ATAC-seq, methylation, CUT&Tag and CyTOF profiles onto scRNA-seq references- scaling to millions of cells. biorxiv.org/content/10.110…
🧬Our citizen-science videogame is officially out today! 🥳 We are launching the #GenigmaChallenge, a collaborative experiment to obtain the genomic map of breast cancer by playing with your smartphone. 📲 Run! Get the app! genigmagame.app/en/
🧬Our citizen-science videogame is officially out today! 🥳 We are launching the #GenigmaChallenge, a collaborative experiment to obtain the genomic map of breast cancer by playing with your smartphone. 📲 Run! Get the app! genigmagame.app/en/
Excited to announce that our paper describing NEAT-seq, a method to simultaneously measure transcription factor protein abundance, ATAC-seq, and RNA-seq in single cells, is out on biorxiv! Congrats to Amy and Ben! biorxiv.org/content/10.110…
Wrote some limericks long back on different areas IGIB works on. Here is one, rest will follow. A Limerick a day!
The Akdemir lab is hiring! We are analyzing human tumor samples with Hi-C & other assays to understand the altered gene regulation in cancer cells. Check out our lab website: akdemirlab.github.io & job post (starting salary $65K + benefits): nature.com/naturecareers/… Please RT!
Our study on chromatin states in metastatic melanoma came out today. We demonstrate genotype-specific chromatin state patterns and suggest use of PRC2 inhibitors in NRAS-mutant melanoma. cell.com/cell-reports/f… @tangming2005 Chris Terranova Mahinur Maitituoheti @MDAndersonNews
Happy to share our recent paper. (b.ersoy style) Cocuk yazmis :) #MachineLearning #DeepLearning #epigenetics #Cancer sciencedirect.com/science/articl…
Happy to have been a part of this study spearheaded by @orouji, @aayushraman & @anandkamalsingh (@raikunal lab), identifying enhancer subtypes in #colorectal #cancer and suggesting potential combination therapies based on such classification. #epigenetics
Happy to have been a part of this study spearheaded by @orouji, @aayushraman & @anandkamalsingh (@raikunal lab), identifying enhancer subtypes in #colorectal #cancer and suggesting potential combination therapies based on such classification. #epigenetics
Excited to share our latest paper on the new epigenomic subtypes of colorectal cancer w/ therapeutic approach | tinyurl.com/kutna4z9 | @Gut_BMJ @MDAndersonNews | @raikunal lab | thanks to @aayushraman @anandkamalsingh et al. | #epigenetics #genomics #colorectal #cancer
Very happy to share new paper from my lab. A step towards precision medicine in colorectal cancers based on their epigenome content. Great effort by @orouji @aayushraman @anandkamalsingh. Thanks to collaborators @skopetz @jsm2334 @evilarsan @MDAndersonNews gut.bmj.com/content/early/…
It takes a village to publish a paper.. special thanks to all the co-authors especially @orouji, @anandkamalsingh & @raikunal and reviewers for their helpful discussions in improving the manuscript.
It takes a village to publish a paper.. special thanks to all the co-authors especially @orouji, @anandkamalsingh & @raikunal and reviewers for their helpful discussions in improving the manuscript.
Spear-ATAC, a method for assaying open chromatin and Crispr guides, is out! Congrats to @Sarah_E_Pierce and @JeffreyGranja nature.com/articles/s4146…
Our manuscript showing tumor suppressor function of KMT2D in melanoma is out today in Cell Reports. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma cell.com/cell-reports/f…

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