Eamon McAndrew @eamon_mcandrew

Marie Curie funded PhD candidate at IPMC Sophia Antipolis. long-read single-cell transcriptomics. Interested in biology, deep learning & tech! 🔬🧬🧠 Galway Joined February 2012

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Steve McCarroll @s_mccarroll

8 months ago

Excited to share the paper: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles are innocuous, just unstable – CAG repeats slowy expand throughout life. We call it a "ticking DNA clock". cell.com/cell/fulltext/…

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Stephen Turner 🦋 @stephenturner.us @strnr

9 months ago

Borzoi was published yesterday: Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation nature.com/articles/s4158… 🧬🖥️🧪 github.com/calico/borzoi (apache)

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Yair Einhorn @yaireinhorn

9 months ago

1/🚨WOW! $SANA announced initial positive results from its first-in-human study of UP421 - an allogeneic primary islet Cell Therapy engineered with Sana’s proprietary hypoimmune (HIP) technology for patients with type 1 Diabetes, without the use of any immunosuppression $XBI 🧵👇

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AnaConesa @anaconesa

9 months ago

Proud of @Conesa_Lab and @MSCActions @LongtrecEU amazing doctoral candidate @Tian_Yuan_Liu for this timely and comprehensive review on how #LongReadSequencing can profile the epigenome to reveal complex chromatin states. Published today in @NatureGenet. nature.com/articles/s4158…

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François Fleuret @francoisfleuret

9 months ago

GANs are temperamental capricious and demanding models. They may throw a bunch of NaNs in your face at any moment because why not. Autoencoders and transformers are hard-working and tranquil.

MinotaurOnLucy @minotauronlucy

9 months ago

GANs are temperamental capricious and demanding models. They may throw a bunch of NaNs in your face at any moment because why not. Autoencoders and transformers are hard-working and tranquil.

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Jorge Bravo Abad @bravo_abad

9 months ago

Programmable trans-splicing riboregulators for complex cellular logic Synthetic biology has long sought to harness the power of living cells as programmable machines, but progress has been constrained by a limited repertoire of regulatory tools. Traditional RNA-based regulators…

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Jeremy Howard @jeremyphoward

9 months ago

SW eng manager: No real work gets done in Jupyter notebooks. Alex Radford: I invented GPT and CLIP in Jupyter notebooks.

Zach Dive @zachdive

9 months ago

SW eng manager: No real work gets done in Jupyter notebooks. Alex Radford: I invented GPT and CLIP in Jupyter notebooks.

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bioRxiv Bioinfo @biorxiv_bioinfo

9 months ago

scMusketeers: Addressing imbalanced cell type annotation and batch effect reduction with a modular autoencoder biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

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Pálás Cinema @PalasGalway

9 months ago

It is with deep regret that after seven years of trading, Pálás will be closing its doors at the end of February 2025. To many, Pálás is more than just a cinema and we have loved being a part of the community.

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Eric Vallabh Minikel @cureffi

10 months ago

Today we introduce a new drug candidate for prion disease: a PrP-lowering divalent siRNA. A 4-year collaboration with @RTI_UMassChan enabled by @NINDSfunding IGNITE & URGenT mechanisms. biorxiv.org/content/10.110… Our hope is to advance this to the clinic, wish us luck!

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CZI Science @cziscience

10 months ago

Today we’re sharing an initial set of cell models that bring together #SingleCell & imaging data in a centralized place. They come with a suite of resources so they’re easy to run + further develop to quickly uncover the mechanics of how cells work czi.co/4g1jTSa

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InstaDeep @instadeepai

10 months ago

🎉Big news! Our Nucleotide Transformer foundation models for genomics have been published in @naturemethods! The models pave the way for progress in ML and genomics, redefining our approach to genomics prediction tasks and enabling improved performance over specialized methods…

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Boxiang Liu @boxiangliu

10 months ago

Our paper on single-cell splicing QTL is now published as a cover article in Nature Genetics. nature.com/articles/s4158… Congratulations to co-first authors @chitian51616, @Yihan720, and Yuntian Zhang! Huge thanks to AIDA leaders @shyam_lab , Woong-Yang, @JayShin and Kian Hong!

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Alex Rives @alexrives

10 months ago

Introducing ESM Cambrian. Unsupervised learning can invert biology at scale to reveal the hidden structure of the natural world. We’ve scaled up compute and data to train a new generation of protein language models. ESM C defines a new state of the art for protein…

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Nature Methods @naturemethods

10 months ago

Nucleotide Transformer is a series of genomics foundation models of different parameter sizes and training datasets which can be applied to various downstream tasks by fine-tuning. @instadeepai nature.com/articles/s4159…

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Eric Topol @EricTopol

10 months ago

Some very good news for people with asthma and COPD. The first new treatment for acute attacks in over 50 years—a monoclonal antibody vs interleukin-5 receptor-α—with efficacy in a randomized trial thelancet.com/journals/lanre… @LancetRespirMed @SanjayResp @MonaBafadhel @kingsmedicine

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EMBL-EBI Jobs @EMBLEBIjobs

10 months ago

🚀 We're hiring a Full Stack Software Developer for the RNA Resources team! Work with cutting-edge tech (Django, React, Kubernetes) to develop world-leading RNA databases like Rfam & RNAcentral. Shape RNA research globally! #FullStack #DeveloperJobs embl.org/jobs/position/…

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SophI.A Summit @Summitsophia

10 months ago

[SophI.A Summit - DAY 1] - Official Launch of the SophI.A Summit 2024! 📢 Today, the SophI.A Summit 2024 officially opens with the Opening Ceremony in the presence of Jean Leonetti, Charles Bouveyron, Marco Landi, and Jeanick Brisswalter.

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Cell @CellCellPress

10 months ago

In the latest issue! Small and long non-coding RNAs: Past, present, and future dlvr.it/TGQ69B

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Richard Song @XingyouSong

10 months ago

LLM embeddings are surprisingly great for high dimensional regression. Why? Because they preserve Lipschitz continuity better than traditional methods! But bigger models aren’t always better, due to confounding factors like RL-HF. Tweeting on behalf of @erictang000 whom I had a…