James Torpy @jamesRtorpy
PhD student at the Garvan Institute in Sydney, studying repetitive genomic elements (and ncRNA from!) in genomically unstable cancers Sydney, New South Wales Joined September 2018-
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Following181
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James Torpy retweeted
My PhD work is out at last!! We uncovered a new role for ID4 in repressing HEB-mediated myoepithelial differentiation of breast stem cells using tg mice, organoids, RNA-seq, RIME & ChIP-seq 🍾 Thanks to my boss supervisors @dralexswarbrick @SimonJunankar cell.com/iscience/fullt…
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Exciting paper recently published in our lab highlighting the role of an inflammatory subtype of cancer-associated fibroblast (iCAF) in cytotoxic T-cell dysfunction with significant clinical implications! Check out the mini tweetorial...
Exciting paper recently published in our lab highlighting the role of an inflammatory subtype of cancer-associated fibroblast (iCAF) in cytotoxic T-cell dysfunction with significant clinical implications! Check out the mini tweetorial...
James Torpy retweeted
We are really excited that our work showing how pervasive lesion segregation shapes cancer genome evolution is published today in @Nature. nature.com/articles/s4158… Here’s a #tweetorial to explain our #LesionSegregation findings... [1/13]
James Torpy retweeted
Excited to share another preprint from the @dralexswarbrick lab, describing the heterogeneity of stromal cells in triple-negative breast cancers. Collabs with @XShirleyLiu, Elgene Lim, @paultimpson7 @thomasrcox + many more. Pls share and RT! Summary👇 biorxiv.org/content/10.110… 1/5
James Torpy retweeted
Presenting my first preprint benchmarking the cryopreservation of human cancers for scRNA-seq. Work involved many from @dralexswarbrick lab + collaborators from @GarvanInstitute @SVHSydney @COBLH @MelanomaAus. Pls share and RT ! Summary below 👇 biorxiv.org/content/10.110…
James Torpy retweeted
A collaborative study with Roger Reddel’s lab is out now in @J_Cell_Sci. Pleased to have contributed automated imaging and analysis tools to aid their mechanistic study which found that ATRX and PML protein level is an identifier of cancer cell suceptibility to oncolytic HSV-1.
A collaborative study with Roger Reddel’s lab is out now in @J_Cell_Sci. Pleased to have contributed automated imaging and analysis tools to aid their mechanistic study which found that ATRX and PML protein level is an identifier of cancer cell suceptibility to oncolytic HSV-1.
James Torpy retweeted
RAGE-SEQ at #KSsinglecell ! @ManuSinghNZ from @GarvanInstitute describing a powerful scRNA-Seq + targeted long read seq approach with many applications in tumour immunology.
James Torpy retweeted
Combo of tech & informatics, we present RAGE-seq. @10xGenomics & @illumina single cell seq & targeted @nanopore seq of antigen receptors in a breast #cancer tumour & draining lymph node. @dralexswarbrick @martinalexsmith @GammyAL @ManuSinghNZ @carsweshau biorxiv.org/content/early/…
James Torpy retweeted
Introducing Seave for precision medicine variant interpretation. It handles WGS-sized data, uses #gemini for SNV and Indels, and provides CNV and SV support, an annotation engine, and sharing with collaborators academic.oup.com/bioinformatics…
Introducing Seave for precision medicine variant interpretation. It handles WGS-sized data, uses #gemini for SNV and Indels, and provides CNV and SV support, an annotation engine, and sharing with collaborators academic.oup.com/bioinformatics…
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