José Xesspe @josecaxeca
Joined May 2009-
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4. Cut caffeine by 2pm. Having 400mg (4 cups) even 6 hours before bed cuts your sleep by 41 minutes. Half that amount still disrupts sleep.
The good news? You can stop this cascade: 🧠 Prioritise 7-8h sleep ⚡ Morning sunlight exposure 🥑 Stop eating 3h before bed ☕ Limit caffeine after 2pm 💊 Consider melatonin Thanks for reading and repost/like below if you think someone else might enjoy it too. Or read more…
The good news? You can stop this cascade: 🧠 Prioritise 7-8h sleep ⚡ Morning sunlight exposure 🥑 Stop eating 3h before bed ☕ Limit caffeine after 2pm 💊 Consider melatonin Thanks for reading and repost/like below if you think someone else might enjoy it too. Or read more…
New research reveals sleep loss triggers the same metabolic dysfunction seen in Alzheimer's. Here's the mechanism – and the fixes that work:
Un hallazgo inquietante: las infecciones durante el embarazo podrían dejar cicatrices invisibles en el cerebro del bebé, aumentando el riesgo de autismo y esquizofrenia años después. 👇
Mitochondrial health is crucial for overall health. Several nutrient and non-nutrient compounds have evidence for supporting mitochondrial function and health. Of note, regarding their effects on mitochondrial health, it is typical that most research concerning this topic is…
Creatine - therapeutic applications beyond athletic performance Creatine, a well-established ergogenic aid in sports, is now being investigated for its potential therapeutic applications in various medical domains, including neuropsychiatric disorders, heart failure, etc.…
La gran importancia del eje intestino-cerebro 🧠 La microbiota intestinal modula el eje HPA (estrés ↔ cortisol) y con ello procesos clave como memoria, aprendizaje y emociones. 🔹Cuando hay disbiosis o estrés crónico, el eje se altera: aumenta la inflamación, se afecta la…
Sleep deprivation is a catabolic stressor. This leads to reduced testosterone and increased cortisol → muscle loss, insulin resistance, and mood disturbance.
Our paper was just published in the Journal of Psychiatry & Brain Science. 5 grams of creatine per day saturates your muscles, but is likely too low for the brain. 🧵1/10
Exercise releases anti-cancer myokines that suppress tumor growth New RCT in breast cancer survivors shows 20-29% in vitro reduction in cancer cell growth from a single workout
Exercising 4h after learning enhances activation of the hippocampus & improves memory retention. Exercising immediately after has no effect.
CURRENT HUMAN APPLICATIONS: 💊 Available Now: • Exercise boosts Klotho production 30-50% 🏃♀️ • Vitamin D3 supplementation increases levels 🌞 • Caloric restriction activates Klotho pathways 🍽️ • Cold exposure stimulates production ❄️ • Quality sleep optimizes Klotho…
Hierarchy of health: 1. Sleep 2. Circadian rhythm alignment 3. Nutrition 4. Body composition 5. Social relationships 6. Exercise * my opinion. All of these factors matter and optimal health is a balance of them all
Regular exercise reduces the likelihood of plaque accumulation in the arteries However, many long-term exercisers appear to have coronary artery calcification, indicating atherosclerosis progression The fascinating thing is that despite the higher plaque, those people still…
A new research from Taiwan found that SARS-CoV-2 damages mitochondria in infected cells, reducing energy production and increasing oxidative stress even after the virus is gone. This lasting mitochondrial injury may drive #LongCOVID symptoms including fatigue and brain fog.…
Creatine is not only for athletes or optimizing cognition, it can protect you against muscle loss during injury. @BrandonLuuMD reveals creatines massive potential. Full episode: youtu.be/Twl6hpvjc0E

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