Peter Openshaw @p_openshaw
Mucosal immunologist and respiratory physician, working on lung infections (esp. COVID, RSV and influenza) at Imperial College London. imperial.ac.uk/people/p.opens… London, England Joined September 2017-
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"We hope that our work opens the way to the development of specific tests and treatments for the various types of long COVID and believe that a ‘one size fits all’ approach to treatment may not work" @p_openshaw imperial.ac.uk/news/252415/lo…
Our latest #LongCovid research from @PHOSP_COVID & @CCPUKstudy has found inflammatory patterns across different symptoms. The work brings us closer to understanding long COVID and finding treatments. Thanks to all co-authors @p_openshaw @InThwaiteImmune & @ClaudEfstathiou
'With 1 in 10 #SARSCoV2 infections leading to #LongCOVID and ~65million people globally suffering ongoing symptoms, we urgently need more research to understand this condition. At the moment, it’s very hard to diagnose and treat'. @p_openshaw @ImperialNHLI ukri.org/news/long-covi…
Prospective, longitudinal data with a contemporaneous non-cancer cohort has enable us to make important novel observations in regard to cancer patients on treatment & admitted with COVID @LanceTurtle ⬇️ this demonstrates power of national pandemic planning @ISARIC1 @CCPUKstudy
Prospective, longitudinal data with a contemporaneous non-cancer cohort has enable us to make important novel observations in regard to cancer patients on treatment & admitted with COVID @LanceTurtle ⬇️ this demonstrates power of national pandemic planning @ISARIC1 @CCPUKstudy https://t.co/QZFAD7Jy5F
This year's International Day of Immunology will be Monday, April 29th! This year's theme is #ImmunityAndAging! Register for our #DayofImmunology webinar: loom.ly/M63fa6w Learn about our social media contest for national and regional societies: loom.ly/yWRSIP0
We are hosting a free public talk by DAME SARAH GILBERT at @imperialcollege on 'Vaccine development in a pandemic'. All welcome, register here: eventbrite.co.uk/e/vaccine-deve… Please RT
We’re pleased to share our latest analysis of the ISARIC4C CCP-UK dataset of patients hospitalised with COVID in the UK, looking at patients having treatment for cancer over the first two years of the pandemic. sciencedirect.com/science/articl…
The data highlight the robust working of our immune system, with concentration on conserved parts of the pathohen. SARS-CoV-2 has many epitiopes and will not overcome vaccine or infection induced immunity. x.com/Marc_Veld/stat… 10/10
The data highlight the robust working of our immune system, with concentration on conserved parts of the pathohen. SARS-CoV-2 has many epitiopes and will not overcome vaccine or infection induced immunity. x.com/Marc_Veld/stat… 10/10
Congratulations to Dr. Gagandeep Kang, recipient of the 2024 John Dirks Canada Gairdner Global Health Award!
“Long Covid blood clues could prompt future trials” “People with long Covid have evidence of continuing inflammation in their blood, which could help understanding of the condition and how it may be treated, a UK study suggests” bbc.co.uk/news/health-68…
We are really please to have our paper on Long Covid subtypes out today in @NatImmunol. This project worked with @PHOSP_COVID cohort to delve into what is different in those with persistent symptoms. nature.com/articles/s4159… Here's a short thread on what we found:
@PHOSP_COVID @long_covid @p_openshaw @FelicityLiew @rhyanthwaites 🌟 Great coverage @BBCNews 🙏 🌟 positive for public to hear about the underpinning biology for #LongCovid 🌟 more next week about a clinical trial finally started 🌟 much to do - plans +++ #LongCovid 👇👇👇
@PHOSP_COVID @long_covid @p_openshaw @FelicityLiew @rhyanthwaites 🌟 Great coverage @BBCNews 🙏 🌟 positive for public to hear about the underpinning biology for #LongCovid 🌟 more next week about a clinical trial finally started 🌟 much to do - plans +++ #LongCovid 👇👇👇 https://t.co/ieXVns1H1I
Cabinet Office question from @elliereeves on no. people in UK currently out of work due to #LongCovid. Answer given 🔴Most recent estimate July ‘22 - 375,000 🔴Nov 23 - Jan 24 - 2.7m not working/seeking work due to long-term sickness/disability. Can’t say how many due to LC
Subtypes of #LongCovid indicating specific immune/inflammation markers and pathways related to principal symptoms nature.com/articles/s4159… @NatImmunol by @FelicityLiew @ClaudEfstathiou @p_openshaw @InThwaiteImmune and their collaborators across the UK
Kenneth Clark was such a great man. Did the cigarelloes he smoked on camera kill him?
A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results nature.com/articles/s4159…
💫 Today is #vaccine engagement day! 💫 We'll be sharing resources & amplifying expert voices to help everyone make informed decisions about childhood #vaccinations Our new #measles infographic answers common questions & highlights the importance of the #MMR vaccine 1/2 🧵
"Unfortunately, in public policy, pandemic preparedness is all too often relegated to the cash-starved budgets of development agencies or squeezed into strained health budgets"
"Unfortunately, in public policy, pandemic preparedness is all too often relegated to the cash-starved budgets of development agencies or squeezed into strained health budgets"
Nice account of where we are with #COVID_19 from @BristOliver open.substack.com/pub/bristolive…
Proud to have Prof. Peter Openshaw @p_openshaw as a keynote speaker at #GfV2024! Fantastic insights into RSV, a notoriously underrated respiratory virus causing high morbidity among infants but also elderly every winter season. Will the new vaccines end the tragedy?
Stephen Griffin @SGriffin_Lab
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Resident tissue macrophages: Key coordinators of tissue homeostasis beyond immunity | Sci Immunol science.org/doi/10.1126/sc…
We have just wrapped up #RECOVERYmeeting2024. It was a huge success thanks to the amazing work of the @OUCRU_Programme team. Working on #RECOVERYTrial has been one of the highlights of my career!
The West Midlands currently has the highest hospital admission rates by region.🗺 You can read the full report here: gov.uk/government/sta…
A nuanced understanding of myeloid C-type lectin receptors' interactions with endogenous and microbial triggers is starting to uncover the context-dependent nature of their roles in #InnateImmunity, reports Drs. Reis e Sousa @TheCrick and co-authors. bit.ly/4cYX1Bv
🚨Study on #LongCovid phenotyping, identifying potential treatments.⬇️ Thanks to our members for their work as part of the @PHOSP_COVID Collaborative Group! "findings…support use of antiviral or immunomodulatory agents in controlled therapeutic trials” nature.com/articles/s4159…
"We hope that our work opens the way to the development of specific tests and treatments for the various types of long COVID and believe that a ‘one size fits all’ approach to treatment may not work" @p_openshaw imperial.ac.uk/news/252415/lo…
Congratulations to AAI President Akiko Iwasaki for being named one of Time's most influential people of 2024! @VirusesImmunity @TIME @YaleCII time.com/collection/100…
Morning Vancouver. Looking forward to #TED2024
There are some who understand that the future doesn’t just happen — it’s made. Among these are the TED Fellows: innovators, activists, artists, inventors and dreamers. Meet the class of #TED2024. blog.ted.com/meet-the-2024-…
Comprehensive overview of literature on (pathogenesis of) post acute COVID syndrome. nature.com/articles/s4141…
We have learned so much from this pandemic. Next step is: can we optimize vaccination schemes to reduce this initial exposure bias? Timing between boosters has shown an effect, for instance. More to learn here
I have highlighted many papers over the past year that show this; a more rapid and robust response of those cells that recognise parts of SARS-CoV-2 that is conserved between the initial response and the subsequent one. Important: this does not prevent new responses. 3/10
Many congratulation. An obvious choice for working selflessly for so many with so little
Congratulations to Dr. Gagandeep Kang, recipient of the 2024 John Dirks Canada Gairdner Global Health Award!
The largest genome-wide association study for type 2 diabetes so far, which included several ancestry groups, led to the identification of eight clusters of genetic risk variants go.nature.com/3xzZ27i
Subtypes of #LongCovid indicating specific immune/inflammation markers and pathways related to principal symptoms nature.com/articles/s4159… @NatImmunol by @FelicityLiew @ClaudEfstathiou @p_openshaw @InThwaiteImmune and their collaborators across the UK
8,000 possible H5N1 exposures [between 9 February 2022 to 29 March 2024] are currently under investigation, according to Dr Joshua Mott, WHO senior advisor on influenza, in an article in the Telegraph.
🚀Exciting news!📢 Our latest article "Thioredoxin is a metabolic rheostat controlling regulatory B cells" has just been published in @NatImmunol! Thioredoxin fuels Breg differentiation. SLE B cells show mitochondrial chaos. Thioredoxin fixes the mess!💥 See below for details ⬇️
A new study shows how a #COVID19 #CoVLP vaccine adjuvant induces robust and broad memory #Bcell response. @GSK @medicagoinc Learn more: scim.ag/6xV
Could be significant: CBS is launching a new show as part of its pivot to streaming. It's called "CBS News Confirmed." Devoted to combatting misinformation. "Mission is to identify and fight the spread of false stories, conspiracy theories and bad facts." variety.com/2024/tv/news/c…