Mark Peters @pus27
Joined May 2011-
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Editorial Commentary on @OxyPicu trial with @Doug_Gould1 Thanks @PedCritCareMed and @RobertCTasker for the chance to say some of things we couldn't fit in the main trial discussion tinyurl.com/mtjy35ah @NIHRresearch @ICNARC @PICSociety @PICJournalWatch @PaulMouncey @pic_pram
@lyvonnetume @pus27 @PICJournalWatch @PicPod_Podcast @ICNARC @NIHRresearch @APMIC_Imperial @mjcarterhealth @DrSamRay @SarahESeaton @PICANetAudit PCCS-SG Spring Meeting: OXFORD 22/23 MAY 2024
Research explored the oxygen levels of critically ill children in intensive care. The study found that with reduced oxygen targets: 💙50 more children would survive in the UK each year 💰 the NHS could save £20 million per year. Read the evidence: evidence.nihr.ac.uk/alert/children… @pus27
Clear signal of benefit of a Lower Oxygenation Target in a MCRCT. Support for @OxyPicu result - time to implement if you haven’t already? @PICSociety @ESPNIC_Society @PALISInet @ICNARC Super work. @AndersPerner jamanetwork.com/journals/jama/…
There is a crisis in clinical academia in the UK. We talk of the need to expand medical schools, embed research into the NHS to improve care, & the importance of a vibrant life sciences sector for the economy of the UK, & yet we seem unable to tackle the underlying issues 1/9
I've waited seven years for this moment. "There was truth and there was untruth, and if you clung to the truth even against the whole world, you were not mad." George Orwell, 1984
I've waited seven years for this moment. "There was truth and there was untruth, and if you clung to the truth even against the whole world, you were not mad." George Orwell, 1984
#pediatric #sepsis definitions discussion here, relevant for #pem. In our world, sepsis is not a screening tool - we need to treat more than the children who meet these criteria. This definition can be an outcome to drive our research forward on better screening.
#pediatric #sepsis definitions discussion here, relevant for #pem. In our world, sepsis is not a screening tool - we need to treat more than the children who meet these criteria. This definition can be an outcome to drive our research forward on better screening.
Great to see the huge level of interest in our @PICSociety @ICNARC @NIHRresearch trial in @TheLancet . @pic_pram @PaulMouncey @Doug_Gould1 @DavidHarrison80 @DrSamRay @catsretrieval @STRS_Evelina @UHS_PICResearch @GreatNorthCH @PICJournalWatch @BristolPICRese1 @OxyPicu
Great to see the huge level of interest in our @PICSociety @ICNARC @NIHRresearch trial in @TheLancet . @pic_pram @PaulMouncey @Doug_Gould1 @DavidHarrison80 @DrSamRay @catsretrieval @STRS_Evelina @UHS_PICResearch @GreatNorthCH @PICJournalWatch @BristolPICRese1 @OxyPicu
Folks, tomorrow we’ll be announcing the NEW PEDIATRIC SEPSIS CRITERIA @SCCM! A huge multinational and multidisciplinary effort, based on the largest data-driven effort of the kind (>3.6M peds encounters). Concurrent publications in @JAMA_current! #sccm2024 #PedsICU #DataScience
Folks, tomorrow we’ll be announcing the NEW PEDIATRIC SEPSIS CRITERIA @SCCM! A huge multinational and multidisciplinary effort, based on the largest data-driven effort of the kind (>3.6M peds encounters). Concurrent publications in @JAMA_current! #sccm2024 #PedsICU #DataScience
Amazing effort from all 16 PICUs ! we’re nearly at our 1000th recruit ! @ICNARC @NIHRresearch @pus27 @PICSociety @edgehill_HRI
@OxyPicu fue un ensayo clínico controlado en 15 #PedsICU británicas y encotró que quizás MENOS es MAS en Oxigenación Objetivo. Sat 88–92% o liberal (SpO2 >94%) ?thelancet.com/journals/lance……@TheLancet @pus27 @ICNARC @DrSamRay @pic_pram @KathyRowan101
Just published at PicPod.net, PicPod77 on the OxyPICU trial results with study lead Mark Peters @pus27. It's a blockbuster trial for #PedsICU, with results which should impact management globally. How was it done, what do the results mean, and how can we implement?
How should we decide how to treat the child: harm versus best interests in cases of disagreement academic.oup.com/medlaw/article… Nice to see this one in print - thanks Emma & Dave, don’t think we are on the fence @PCCS_UK @uclbioethics @GOSH_PGME
Aiming for lower oxygen targets in critically ill children being ventilated in intensive care could save lives and reduce the length of time that organ support is needed, a large UK-wide study has shown bmj.com/content/383/bm…
In depth presentation of the @OxyPicu results and discussion thanks the brilliant @CritCareReviews team. @ICNARC @NIHRresearch @TheLancet @GreatOrmondSt @UCL_RCCA @PICJournalWatch @PICSociety @OPENPediatrics @ESPNIC_Society @PALISInet @anzicsctg @KathyRowan101 @Lem_Exeter
In depth presentation of the @OxyPicu results and discussion thanks the brilliant @CritCareReviews team. @ICNARC @NIHRresearch @TheLancet @GreatOrmondSt @UCL_RCCA @PICJournalWatch @PICSociety @OPENPediatrics @ESPNIC_Society @PALISInet @anzicsctg @KathyRowan101 @Lem_Exeter
Great to see this important PICU trial published, comparing SpO2 of 88-92% vs >94% in critically ill kids. TL:DR conservative oxygen gets you off organ support faster, with no evidence of harm (mortality non-significantly down, but PiCU mortality is low) thelancet.com/journals/lance…
Extremely important results showing us that many more trials should be done in pediatric ICU patients
Extremely important results showing us that many more trials should be done in pediatric ICU patients
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial - if you are interested what the authors say about this practice changing trial come to #sccm2024 thelancet.com/journals/lance…
A landmark NIHR-funded study has found that reducing oxygen levels for children in intensive care will save lives. The Oxy-PICU study was led by researchers from @GreatOrmondSt and @UCLHresearch. Read more: nihr.ac.uk/news/reducing-…
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Chris Tomlinson @tomlincr
1K Followers 869 Following 👨💻Health Data Scientist |🎓PhD in AI Healthcare @ucl @cdt_ai_health |👨⚕️Critical Care Doctor
Dr Martí Pons @DrMartiPons
537 Followers 260 Following
Early Doors @EarlyDoorsClips
62K Followers 752 Following Early Doors fan account. Content not owned. To the regiment 🍻
Alex Menn @_AlexMenn
334K Followers 2K Following Partner at Begin Capital, VC, angel investor, and entrepreneur
Fesshole 🧻 @fesshole
1.1M Followers 600 Following Confess your sins anonymously - will the internet absolve you? 👖 Sponsored by @hebtroco - buy their lovely trousers 🩳 Buy *NEW* book https://t.co/opfREXuSjI
Vic and Bob @IsItTrue_false
74K Followers 8 Following Welcome! - Vic and Bob clips - True or false questions from Shooting Stars - Fan run by @Gabba_Gabba_Lou
Ranjit Bhose @RanjitBhose
13 Followers 0 Following
I ran the London Landmarks half-marathon for nacoa.org.uk, a wonderful charity supporting the children of parents with alcohol addiction. Not a pretty sight but made it! Next challenge is a 20 mile walk around the Peak District in May (#JustGiving link below)....
Amazing work to all 17 sites! only 58 patients off our pilot target of 1500! @ICNARC @NIHRresearch @lyvonnetume @pus27 @PICSociety
Researchers explored the level of oxygen children in intensive care need. With lower oxygen targets: 🧒50 children would be saved each year 💊children would spend less time on life-support 💸the #NHS would save £20 million per year bit.ly/49dDXwA @pus27 #patientsafety
@EP_AnimalLovers @ThrillaRilla369 Our dog's don't know how to use apostrophe's.
The most fantastic achievement - recruiting ahead of target! Thanks to everyone who is making @neogastric such a success!
It’s astonishing to see @neogastric reaching another recruitment milestone so soon. Over 800 babies recruited!! Congratulations to everyone involved, especially the hospital teams that work so hard for these recruits 🌟🌟 @NPEU_Oxford @NPEU_CTU
#pediatric #sepsis definitions discussion here, relevant for #pem. In our world, sepsis is not a screening tool - we need to treat more than the children who meet these criteria. This definition can be an outcome to drive our research forward on better screening.
Important commentary. The Phoenix criteria is for diagnosis of sepsis (that is, infection with life-threatening organ dysfuntion) and NOT a screening tool for possible sepsis before organ dysfunction is overt. Screening tools should primarily be locally developed and…
Stability of the transcriptome in #PedsICU sepsis. Work presented by med student Josh Hageman Phoenix #SCCM2024 on behalf of @mjcarterhealth. As expected - dynamic evolution of gene expression but stable within patients. @ImperialPaeCH @ImperialBRC @ImperialMed @pus27 @_myrsini_
Folks, tomorrow we’ll be announcing the NEW PEDIATRIC SEPSIS CRITERIA @SCCM! A huge multinational and multidisciplinary effort, based on the largest data-driven effort of the kind (>3.6M peds encounters). Concurrent publications in @JAMA_current! #sccm2024 #PedsICU #DataScience
#sccm2024 special mention to our #pedsicu community who will bring us a new sepsis definition to Phoenix w/ @JAMA_current
Are dichotomised outcomes in #research good or bad?? 😉 Fascinating start from @DavidHarrison80 at #ukccrf24 @ukccrg in #southampton looking at the results from @OxyPicu in more detail @ICNARC @ICS_updates @SouthamptonBRC @pus27
Amazing effort from all 16 PICUs ! we’re nearly at our 1000th recruit ! @ICNARC @NIHRresearch @pus27 @PICSociety @edgehill_HRI
@OxyPicu fue un ensayo clínico controlado en 15 #PedsICU británicas y encotró que quizás MENOS es MAS en Oxigenación Objetivo. Sat 88–92% o liberal (SpO2 >94%) ?thelancet.com/journals/lance……@TheLancet @pus27 @ICNARC @DrSamRay @pic_pram @KathyRowan101
Amazing recruitment for December 241 children ! Fantastic effort to all 16 sites open …. @ICNARC @NIHRresearch @pus27
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial thelancet.com/journals/lance… via @pus27 et al
Just published at PicPod.net, PicPod77 on the OxyPICU trial results with study lead Mark Peters @pus27. It's a blockbuster trial for #PedsICU, with results which should impact management globally. How was it done, what do the results mean, and how can we implement?
#PedsICU #OXYPICU in case you missed it in the last 10 days! @ICNARC @pus27 @DrSamRay @pic_pram et al. @PICSociety
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial hubs.li/Q02c7nrg0
Airway occlusion maneuvers can estimate respiratory effort in invasively ventilated children. This should help us deliver more protective ventilation and understand how much our patients are contributing to ventilation. #PedsICU. @PALISInet link.springer.com/article/10.118…
How should we decide how to treat the child: harm versus best interests in cases of disagreement academic.oup.com/medlaw/article… Nice to see this one in print - thanks Emma & Dave, don’t think we are on the fence @PCCS_UK @uclbioethics @GOSH_PGME
Important Results, Best Science, Evidence Based Medicine. @OxyPicu
In depth presentation of the @OxyPicu results and discussion thanks the brilliant @CritCareReviews team. @ICNARC @NIHRresearch @TheLancet @GreatOrmondSt @UCL_RCCA @PICJournalWatch @PICSociety @OPENPediatrics @ESPNIC_Society @PALISInet @anzicsctg @KathyRowan101 @Lem_Exeter
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