richardson_lab @richardson_lab
Chris Richardson lab at UCSB. DNA repair. Gene Editing. Relatable. richardsonlab.mcdb.ucsb.edu UCSB, CA Joined March 2019-
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richardson_lab retweeted
Amazing postdoc Eric Aird asked how #CRISPR gRNAs & interferon regulate innate #immunity. He found a wild partnership that balances appropriate response w/ cell death. SP100 builds filaments that kill cells, and SP110 breaks them to keep things in line. biorxiv.org/content/10.110… 🧵
richardson_lab retweeted
Excited to share with you our manuscript describing the endogenous protein La as a mediator of prime editing and the development of our PE7 editor, which can improve prime editing. For more, please check out nature.com/articles/s4158…
richardson_lab retweeted
Our phenomenal lab manager is moving on after 3 great years 😭 We are looking for someone to fill the gap. Great for a graduating senior who wants ~2 years experience before grad school Details: shorturl.at/jknqv
Are there established ways of segmenting a TSS list? I have convinced myself that some transcriptional start sites behave differently than others. It would be nice to see if this signal exists in canonical TSS lists rather than my homerolled and idiosyncratic versions.
Congrats. It was a real pleasure seeing this story come together over the years.
Cool!
It’s October 27th and I have finished writing reference letters for trainees/students for the year. A professional Black Friday.
richardson_lab retweeted
Take a look at our preprint out in bioRxiv. We used structural and biochemical techniques to characterize the function of the N1 domain in Pex6 from yeast.
Take a look at our preprint out in bioRxiv. We used structural and biochemical techniques to characterize the function of the N1 domain in Pex6 from yeast.
Congrats!
How did they map enhancers and silencers I wonder 🤔
How did they map enhancers and silencers I wonder 🤔
Oh.
Congrats, Hannah.
UCSB is building capacity for high throughput cell-based assays. What works or doesn’t work? We do a lot of pooled screens in mammalian cells. I’m interested in anecdotes and/or references where those workflows were automated.
This is fun all around. Good premise. Lot of data/assays. Shot through with great technical solutions (e.g. the PTEN exon). biorxiv.org/content/10.110…
Amazing work on this, Julien.
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