Ruby Pelingon @ruby_pelingon
Biochemistry | Glycoproteomics | Protein Engineering | Postdoc at UQ | @[email protected] Australia Joined November 2022-
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Ruby Pelingon retweeted
For readers interested in approaches to improve the preclinical assessment of immunogenicity risk of engineered antibodies and other protein therapeutics, here's a recent review nature.com/articles/s4157… rdcu.be/enaiR
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Ruby Pelingon retweeted
New Online! N-glycan-dependent protein maturation and quality control in the ER bit.ly/3FfBQPI
Ruby Pelingon retweeted
New review on structural glycobiology in glycosciences: "From enzymes to organelles". Carbohydrate processing enzymes, glycosylation networks in vitro, cryo-ET in direct visualisation of native biology. tinyurl.com/4jnv85xt #glycotime
Ruby Pelingon retweeted
This rate of validation suggests that antibodies should be considered non-specific until proven otherwise: 357 validated out of 1,124 tested. .
Ruby Pelingon retweeted
MCP press| Improving the Depth and Reliability of Glycopeptide Identification Using Protein Prospector. Learn more: mcponline.org/article/S1535-…
Ruby Pelingon retweeted
Sugar symphony: glycosylation in cancer metabolism and stemness dlvr.it/TFps5s
Ruby Pelingon retweeted
Interesting piece about glycosylated RNAs (glycoRNAs): sialylated glycoRNAs are present in human cell lines, and sialylation of glycoRNAs depends on the catalytic isoforms of the oligosaccharyltransferase (OST) complex. tinyurl.com/vhz2rj8a
Ruby Pelingon retweeted
@SMereiter @penningerlab and colleagues introduce a scalable method to profile N-glycans across 20 mouse tissues, revealing tissue-specific glycosylation patterns and novel N-glycan structures #glycotime nature.com/articles/s4146…
Ruby Pelingon retweeted
Protein sequencing is key to understanding cellular signalling pathways and metabolic processes. In their Review, @cees_dekker et al discuss how nanopores enable single-molecule protein sequencing and the identification of post-translational modifications go.nature.com/40ZutV0
Ruby Pelingon retweeted
#glycotime Cell-based glycoengineering of extracellular vesicles through precise ... sciencedirect.com/science/articl…
Ruby Pelingon retweeted
Now this is big! S. aureus vaccine exerts production of high levels of IL-10, resulting in the hyper-α2,3 sialylation of antibodies, which interfere with opsonophagocytic killing of S. aureus. Reviewed in tinyurl.com/2ubfanet, details in tinyurl.com/37hueffa #glycotime
Ruby Pelingon retweeted
Lotsa good stuff here! 🍻
Ruby Pelingon retweeted
🔓 #OpenAccess + Most Read in the past 30 days: "PPI-Affinity: A Web Tool for the Prediction and Optimization of Protein–Peptide and Protein–Protein Binding Affinity" go.acs.org/8av
Ruby Pelingon retweeted
Wondering how #MCC950 inhibits the #NLRP3 #inflammasome? To find out read our new @nchembio article from @inflammasomelab star @Rebecca_Coll! Thanks to @arc_gov_au @nhmrc @UQ_News for funding. @ASImmunology @IMBatUQ Link: go.nature.com/2Ytnd0m (PDF rdcu.be/bBC7s)
Ruby Pelingon retweeted
For Tuesday's Tip, here's how you can animate colored and highlighted 3D models of your molecules natively in PowerPoint. Check out more ways to create attention-grabbing presentations with #ChemDraw that will make your peers jealous: ms.spr.ly/6010iZyae #TuesdayTip
Ruby Pelingon retweeted
Structure–activity studies of Streptococcus pyogenesenzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal #SciRep #MassSpec nature.com/articles/s4159…
Ruby Pelingon retweeted
Out today in @ScienceMagazine: Seeing glycans attached to proteins and lipids - at the *single molecule level*! 🎉🎉🎉 doi.org/10.1126/scienc… #ScienceResearch #glycotime #teammassspec My 1st #tweetorial🧵(1/n) 👇👇👇
Ruby Pelingon retweeted
Thanks again to the entire team of investigators including first authors @KawaharaSRebeca and @JUgonotti for enabling this detailed study of neutrophil glycosylation eurekalert.org/news-releases/…
Ruby Pelingon retweeted
Could RNA rings be the next blockbuster drugs. This nice @Nature piece covers the past, present and future of this exciting modality. nature.com/articles/d4158…
Ruby Pelingon retweeted
3/3 Dr. Karikó and Dr. Weissman were also recipients of the 2021 @GoldGooseAward for their #mRNA therapeutics research! Weissman compares his research partnership with Karikó to mixing chocolate and peanut butter in Reese’s peanut butter cup. More here: goldengooseaward.org/01awardees/mrna
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