Beta Hydroxybutyrate Enjoyer @BHBEnjoyer
Layman. Looking for tips on how to keep BHB above 5.5 consistently BHB Processing Plant Joined December 2022-
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“SNPs in or Near the LDLR Locus Are Likely to be Associated with TNF-α and Other Inflammatory Mediators Inflammation is involved in atherosclerosis, and increased chemokine levels have been shown in heterozygous FH.” @daveketo @LDLSkeptic
Don’t forget the daily dose of your fungal toxin! Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes cell.com/iscience/abstr…
“Fibrin may injure endothelial cells, and in certain works it was possible to demonstrate that deposition of fibrin in the intima precedes LDL accumulation.” —Velican p252
Insulin resistance doesn't just relate to carbohydrate metabolism or dietary factors, it also relates to immune activation and stress. 👇 Important things to understand for those experiencing persistent IR despite low carb interventions.
Insulin resistance doesn't just relate to carbohydrate metabolism or dietary factors, it also relates to immune activation and stress. 👇 Important things to understand for those experiencing persistent IR despite low carb interventions.
🚨🚨🚨The exciting day I've been waiting for for a while has finally come.... the publication of our team's collaborative lipedema case definition paper!🚨🚨🚨 🌎This paper was worked on not only by those of us at the research arm of the Lipedema Project, but from clinicians and…
I’m proud to share the results of my pilot trial investigating the therapeutic effects of a #ketogenicdiet on bipolar and schizophrenia, published in @PsychiatryResJ. 📈 We found promising improvements in BOTH metabolic and psychiatric outcomes: sciencedirect.com/science/articl…
Yes, fat is protein sparing in the context of a ketogenic diet, in at least three ways. 1. Products of fat metabolism like acetone and glycerol are used for GNG 2. BOHB is anti-catabolic 3. The Cori cycle recycles glucose
Yes, fat is protein sparing in the context of a ketogenic diet, in at least three ways. 1. Products of fat metabolism like acetone and glycerol are used for GNG 2. BOHB is anti-catabolic 3. The Cori cycle recycles glucose
Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial. Great work by @ShebaniMD showing the metabolic–psychiatric benefits from ketogenic therapy. sciencedirect.com/science/articl…
“This study demonstrated, for the first time in vivo, that circulating levels of PCSK9 and LPS are associated with a mechanism possibly involving NADPH oxidase activation. Patients with concomitant increase of PCSK9 and LPS showed a higher risk of CVEs.” atherosclerosis-journal.com/article/S0021-…
Yes, it’s ‘only’ a murine model. However, it shows a whopping 96 % reduction in atherosclerosis after an anti-inflammatory diet. Yet, I’m just the 3rd person who shares the study in 8 years? NB, the majority of compounds are strong microbiota modulators. academic.oup.com/jn/article/141…
A newly discovered gut hormone, released specifically in response to dietary cholesterol, suppresses cholesterol synthesis in the liver. Named cholesin. A gut-derived hormone regulates cholesterol metabolism cell.com/cell/abstract/…
My thoughts on the NEJM plastics study after listening to a lot of people much smarter than I
@exfatloss @jefmdawson Pretty well. The satiety is triggered in the brain stem. Once the neural sensors generate enough ROS then they tell the rest of the brain to stop eating. In a rat you can infuse antioxidants in to the brain via the carotid artery and they keep eating. ncbi.nlm.nih.gov/pmc/articles/P…
Especially when carbohydrate restriction has already been successfully implemented by healthcare professionals with first-hand insight (and skin in the game)? @idlake
Especially when carbohydrate restriction has already been successfully implemented by healthcare professionals with first-hand insight (and skin in the game)? @idlake
I have been testing a CKM (continuous ketone monitor) for about a week now. I controlled it many times and it correlates extremely well with blood ketones, actually much more accurately than CGM and blood glucose. Great work from #sibiockm🥳 It can be a useful device especially…
Interesting review on connections between sleep and the therapeutic mechanisms of ketogenic diets for mood disorders. frontiersin.org/journals/psych…
And just like that, I offered a perspective article to the peer-reviewed literature on the use of ketogenic diets as a treatment for mental illness. #psychology #socialwork #counseling #ketogenic #metabolicpsychiatry frontiersin.org/articles/10.33…
Today is a very exciting day! 🧠@KetoCounselor has published this essential piece in Frontiers: "From theory to practice: challenges and rewards of implementing ketogenic metabolic therapy in mental health". Check it out! #mentalhealth #metabolicpsychiatry frontiersin.org/articles/10.33…
Velican on the multiple subtypes of "fatty streak." Could help explain some of the immense confusion around hypothesized progression that results from treating all of these as one class of lesion.
It's been 12 years since Stafstrom and Rho reviewed the potential of KD in diverse neurological conditions, including ALS. Only now we have a case study on improved quality of life. ncbi.nlm.nih.gov/pmc/articles/P… P.S. I don't have access—I'm not sure what "time restricted" means here.
It's been 12 years since Stafstrom and Rho reviewed the potential of KD in diverse neurological conditions, including ALS. Only now we have a case study on improved quality of life. ncbi.nlm.nih.gov/pmc/articles/P… P.S. I don't have access—I'm not sure what "time restricted" means here.
Jørn Hegstad Tallaks.. @jaaayht
11 Followers 87 Following
KO Trading & Research @offshoretactics
562 Followers 1K Following Long Term Position Trader. Contrary thinking on world affairs. Free as can be
Senza for Keto & Fast.. @keto_app
371 Followers 443 Following Coaches, Macros, Meal Plans: What began as a passion project to help our friends and family go keto has touched the lives of more than half a million people.
Tfot @TfotTfot
43 Followers 1K Following
Angie Greenshields @tayakaid
265 Followers 726 Following
Dill @Dill6677
1 Followers 15 Following
Michael Stingl @michaelstingl
2K Followers 4K Following digital resident | passionate about #coworking #ui #ux #photography #agile #lean | product owner #mobile #desktop @owncloud | opinions are my own | he/him
Caitlin @Caitlin02368961
1K Followers 2K Following Holistic Pharmacist Mpharm, Metabolic Nutritionist Paleolithic-Ketogenic Diet advocate for healing 🥩🥚🧀☀️✨Sharing information, NOT giving medical advice.
Kurt Röhrbacher @KurtRoehr
4 Followers 51 Following
MAKE EARTH GREAT AS I.. @mysterydancer1
1K Followers 2K Following fighting for the children, veterans, and homeless! Our world needs to flip right side up! Living in the Land of the Lost.
miguel santos @miguelsantos40
9 Followers 446 Following
Lister Leão @LeaoLister
252 Followers 1K Following
Mark Bski 🇺🇸�.. @MarkBski
6K Followers 3K Following If you have one hand in ice & one in fire, on average you feel ok. Lost 100+lbs keto & fasting. Be hard to kill. Go barefoot. Pureblood. I enjoy photography.
Carbs Free Al-Bhatti @carbsfreehuman
325 Followers 564 Following A Pakistani carnivore. After 2.5 years of keto, doing a strict 0 carb carnivore diet since Sep/2022. Lowered my HBA1C from 11.7 (Mar/2020) to 5.3 (Sep/2020).
00000000000 @kh2p8s6q9g
90 Followers 1K Following
The 40 year old white.. @Patrick75649973
60 Followers 551 Following
David Bezpalec @BezpalecDavid
2K Followers 1K Following PhD candidate at @UniLeiden 🇳🇱 Investigating the effect of exogenous ketones on cognition, brain ageing and ADHD 🧠 Also interested in ageing clocks ⏳
PUFA Diluter @pufadiluter
1K Followers 337 Following
MintK @MintK_
174 Followers 429 Following
Professor Peter Delpu.. @peterdelputte
1K Followers 3K Following Professor of Virology & Vaccinology / Respiratory Viruses / EU Master in Vaccinology / Tracking (Corona)viruses in wastewater
TobikoPop @tobikopop
454 Followers 4K Following CryptoCTO. Cogito, ergo sum. Build the future don’t wait for it to happen.
Rex @RexHodlday
880 Followers 692 Following #Bitcoin, freedom, and self-sovereignty maximalist. Regenerative ranching.
Mark 🟡⚪️🟣�.. @meditationstuff
5K Followers 5K Following Enlightened via https://t.co/bRbwiodDZz Groundlessness, but, like, hyperanalytical. 10k-20k+ hours like water flowing downhill
Thor Torrens @ThorTorrens
14K Followers 3K Following Vitamin A disrespecter - Helio therapist - Health Coach - Athlete - Guiding humans to reach their utmost potential - Questions? DM Me 📩
Dr. Martin Milmaniene @doctormilma
13 Followers 57 Following Médico clínico nutricionista Medicina evolutiva Dieta Keto Ayuno intermitente
Harry @larrington323
88 Followers 1K Following Interests: start-ups, technology, philosophy, consciousness, freedom. Nullius in verba. I have no clue what im doing.
exactly1234 @exactly12316
22 Followers 333 Following
Scott Greenway @scottgreenway7
220 Followers 1K Following USMNT/USWNT Fan. Still remember some German from “studying” there. Also a Puerto Rican speaking Gringo.
LeVortex @LeVortexZen
524 Followers 2K Following 🦠🔬⁉️ 🥩💪😎 🤡🌎🙅 Fr - Eng 🥸I use psyops to control and divide oppositions🤫 🥸j'utilise des psyops pour contrôler et diviser les oppositions🤫
The Power of Ozone | .. @thepowerofozone
1K Followers 365 Following Believer in a Divine Creative Force. I eat meat. I don’t eat liver. Ozone therapy aficionado, aka The Crazy Ozone Lady. I know nothing.
Clarry Kitten @ClarryKitten
88 Followers 524 Following "The society that separates its scholars from its warriors will have its thinking done by cowards and its fighting by fools.”
Slobodan Fuletic @Lone_Swordsman1
82 Followers 296 Following
Arteesun @arteesun
147 Followers 405 Following
Chris DeVocht @UnModded_Human
628 Followers 323 Following Building a better way to optimal health and sustainable weight loss. Don't get stuck in endless "move more eat less" loops.
Gregg Trener Personal.. @gregorkaslewicz
16 Followers 81 Following Personal Trainer inst: https://t.co/bctZLQPPtd
Andreia @andreiafscosta
387 Followers 3K Following
DJ🇨🇦🇮🇹 @domj2924
457 Followers 1K Following 🥩🥓🍳🏀Friendly Carnivore. CPTSD. GAD. Socially anxious. Seasonally depressed. Mood disordered. CPP-D/ODSP. Mom of ♀️👼 & 2 boys. Raising a son w/ADHD/MID.
Bryan Krantz @bakrantz
564 Followers 2K Following Associate Professor of Microbial Pathogenesis University of Maryland, Baltimore
Dr Scott W Murray @DrScottMurray
6K Followers 3K Following NHS Consultant Cardiologist interested in Prevention, Lipoproteins and Cardiac CT. Ex-President @bacpr, Senior Lecturer @LiverpoolCCS, Founder @VCardiology 👍
Carnivore is Vegan @CarnivoreIs
4K Followers 712 Following A carnivore diet is more vegan than veganism. We're here to promote a meat based diet. es or a 9 dettp://carnivoreisvegan.com Pronouns: beef/pork/lamb
Emily Anne @iam_emilyanne
6K Followers 769 Following Changing my diet healed 20+ years of treatment-resistant depression, anxiety, & OCD. #glutenfree #ketodiet #carnivore @ChrisPalmerMD @Metabolic_Mind 🥑🥩🧠
Timothy Nightfall, BS.. @timnightfallMD
121 Followers 72 Following Evidence based CVD prevention ONLY. No grifters/deniers allowed! Polydactyly survivor. Heart disease begins at conception. #PrimordialPrevention #PERIOD
Shebani Sethi, MD @ShebaniMD
4K Followers 285 Following Founding Director, #MetabolicPsychiatry #StanfordMed Faculty #psychiatry & #obesitymedicine clinical researcher in metabolic & mental health #DukeMed Alum #mom
Ann Argabright @ann_seclow
47 Followers 158 Following
raw chicken experimen.. @rawmeatdaddy
4K Followers 872 Following eating raw chicken every day til I get a tummy ache. future Nobel prize winner.
Darius Sharpe @MurseDarius
107 Followers 84 Following
The Power of Ozone | .. @thepowerofozone
1K Followers 365 Following Believer in a Divine Creative Force. I eat meat. I don’t eat liver. Ozone therapy aficionado, aka The Crazy Ozone Lady. I know nothing.
DesignedByNature @DesignedNature
408 Followers 121 Following Love the #science behind life and #health #metabolism #ketones #fat shaped through our #evolution - mod of https://t.co/QB3NypQda8
sabine hazan md @SabinehazanMD
158K Followers 652 Following Gastroenterologist, Researcher, Consultant, Speaker. CEO #progenabiome CEO #author LetsTalkSht #microbiome expert. https://t.co/s9PHV6OtbX
Rob @Th3DietGuy
123 Followers 285 Following Hypotheses on health and aging. Academic mathematician | hobby interests in holistic health, anti-aging.
David Saenger, MD, FA.. @saenger_david
633 Followers 847 Following Cardiologist and ultra runner. 40 ultra finishes, 2 x Sub-24 hour 100 mile, 6 x WSER qualifier, Father of 3, intermittent fasting and low carb advocate
Dana @ZeroCarbHealth
11K Followers 203 Following I have been on a Zero Carb all meat Carnivore diet for 16+ yrs. I'm the founder of website & FB Group ZeroCarbHealth providing support and education about ZC.
Danny @dannyketo88
3K Followers 643 Following Animal based ancestral diet. IF. Ex long term veg. & V. Healed an AI disease & restored my health with #Keto. Now helping people restore theirs. Eat for health!
softfocusnostalgia @SFNostalgia
261 Followers 834 Following Nostr: nprofile1qqs2lfnrqwkrqz96slcuh2u9d378zu2lt9rn4f7j4g3gazeqst23c4qgw30jn
Isabella Cooper @I_mitochondria
9K Followers 119 Following PhD researcher in Ketogenic Science and Hyperinsulinemia. AMRSB. Biochemistry/Physiology/Pathology/Ageing.
Matt Calkins MD MHP @MattCalkinsMD
1K Followers 311 Following Primary Care with focus on Metabolic Health. Weight lifting. Long distance thru-hiking (AT 2014). Husband of @laurabuchananmd!
Garry Lee @Gearoidmuar
4K Followers 559 Following Retd doctor, Consultant Histopathologist.Cyclist, photographer, Fluent Irish, some French and Spanish. Ignore anon trolls. LCHF 9.5y+ 40lb down 9y+
Fabio @change_states
60 Followers 85 Following
Metabolic Health Summ.. @MetabolicSummit
4K Followers 235 Following The world's leading medical & scientific conference on metabolic health & therapy! #MHS2024 was recorded - watch the replay for a limited time👇
Spearman @Jimmygotsoul
1K Followers 3K Following The Sultan's Royal Point Guard, low-carb, price action trader, #HoustonRockets, Left economics #Labor. Come out of your echo chamber. Ellipsis... 👑
Dr Erin Louise Bellam.. @erinlbellamy
2K Followers 980 Following 👩🎓PhD MSc BA MHP CPsychol AFBPsS 🧠 Metabolic Psychiatry Clinician & Researcher 🌐Integrative Ketogenic Research & Therapies @ikrt_org
Dr Jen Unwin-Fork in .. @drjenunwin
26K Followers 2K Following #psychology #solutionfocus #hope #wellbeing #realfood #foodaddiction #sugaraddiction https://t.co/eDyYzlIocv….
Eivor @Eivor_Koy
14K Followers 647 Following Regret is a mirage that leads many off the path. @EivorKoy
Dr Elena Gross, Ph.D... @DrElenaGross
2K Followers 378 Following Oxford neuroscientist, PhD in clinical research (ketosis for migraine), ex-chronic migraineur, CEO & founder of KetoSwiss //Tweets are not medical advice
Dr. Matthew CL Philli.. @drmclphillips
3K Followers 49 Following Metabolic neurologist. My foremost passion is to explore metabolic strategies as potential therapies in our most difficult neurological disorders.
Nicole Laurent, LMHC @KetoCounselor
7K Followers 612 Following I am a mental health counselor that helps people explore and adopt nutritional and metabolic therapies for brain health. Not medical advice.
Dominic D'Agostino @DominicDAgosti2
79K Followers 737 Following Neuroscientist, Believer, Self Experimenter, Csilla's Husband. Enthusiast of Space, Science, Nutrition and Fitness
Diana Rodgers, RD @SustainableDish
24K Followers 1K Following Real Food Nutritionist | Speaker | Author | Sustainable Dish Podcast | Filmmaker/Author: Sacred Cow. Executive Director @globalfoodjust1
Citizen Science Found.. @realCSF
1K Followers 0 Following
Craig Emmerich @emmerich_craig
894 Followers 328 Following Best selling author of “Keto.”, speaker and educator. and amateur photographer. Owner of https://t.co/N2ZHktBMt3 and husband of @mariaemmerich
Michael J @astro_toaster
174 Followers 344 Following
wolf carnivore @WolfCarnivore
629 Followers 372 Following Adventures of a Carnivore in the World of Mainstream Nutrition
Trader Mick @TraderMick_
148 Followers 2K Following
Filip Nilenius @rawanimalfoods
1K Followers 706 Following PhD in Structural Engineering. Raw carnivore. Technology is what makes humans thrive on this planet. INTJ. Happily engaged. DM me only about meat.
The Carnivorous Entom.. @CarnivoreAntMan
4K Followers 579 Following The raw meat eating, sword swinging, ant crazy entomologist! Certified Applicator and Board Certified Entomologist (General, Urban, Pest, Medical & Veterinary)
carnivorycon @carnivorycon
833 Followers 0 Following The Original Carnivore Conference: leading edge talks on the science behind low-no plant diets.
Peter Ballerstedt @GrassBased
17K Followers 3K Following Forage agronomist: Ruminant agric; human diet & health. Opinions are my own, not of the organizations I am affiliated with. Intro video https://t.co/npOUlvjr2a
Khurram Nasir @khurramn1
7K Followers 3K Following Husband, Father/ Preventive Cardiologist/Health Policy/ Social Justice & Health Equity/Big Data Applications
Jeffry Gerber, MD @JeffryGerberMD
32K Followers 3K Following Jeffry N. Gerber, MD - Board Certified Family Doctor, Denver's Diet Doctor, Heart Health, LDL-the-Innocent, BHRT, Aging Gracefully, Low Carb Conferences Founder
NOT brought to you by.. @zerocarbage
849 Followers 119 Following T1 Diabetic. In pursuit of normal blood glucose levels 24/7 not “time in range”. 🥩💪
Ancestrally Inconsist.. @AncestralTho
129 Followers 153 Following I would rather live like a modern civilization than fling shit amongst the baboons
TheJournalOfKetosis @KetosisJournal
95 Followers 47 Following Dedicated to publishing the latest science on ketosis
Root Causing Health @rootcausing
167 Followers 36 Following We're 2 software engineers (@nathanequalsone/@nickandre) in Seattle attempting to upend health/nutrition research! https://t.co/Xpbxfav4CB
Bret Scher, MD @bschermd
45K Followers 720 Following Director of Metabolic Mind. Connecting metabolic health and mental health. Also, Low Carb Cardiologist, promoting cardiovascular and metabolic health.
Chris @LipidsN1
141 Followers 237 Following In the Pursuit of Research. Nutraceuticals, lipids and stock analysis fascinate me. Walking lab experiment; N=1. Let’s all get healthy through trial/error 🇬🇷
@sudas1891 @EddieRDMD @_atanas_ Acorns? I mean, c'mon. What sort of subsistence level crap are they? Must have been hard times...
@EddieRDMD @_atanas_ smithsonianmag.com/smart-news/hun…. This one group had a plant based diet and they suffered disease. There is a paucity of dental caries in other”hunter-gatherer” groups preceding this which suggests that this plant based diet was the exception not the norm
@raphaels7 @realDaveFeldman Growing up in the 90s I knew Dr's who smoked and drank. I guess that was screaming to their pts that such habits were harmless 🤷♂️
@nickandre @daveketo @LDLSkeptic Probably has effects on clotting too, but yea pretty much!
@daveketo @LDLSkeptic If your LDLR is busted, you can’t clear endotoxins effectively, I would suspect.
“SNPs in or Near the LDLR Locus Are Likely to be Associated with TNF-α and Other Inflammatory Mediators Inflammation is involved in atherosclerosis, and increased chemokine levels have been shown in heterozygous FH.” @daveketo @LDLSkeptic
@NathanEqualsOne @daveketo @LDLSkeptic So an LDLR mutation that increases LDL-C in serum reduces LDL-mediated clearance of LPS, increasing immune activation and subsequent increased atherogenesis. I love mechanistically upstreaming all the LDL fans 🕺
@Drlipid Here's my hypothesis: Infection is associated with a huge increase in MI risk. LDL binds LPS/LTA from bacteria. LDLR clears this LPS/LTA. PCSK9i drugs upregulate LDLR, increasing clearance capacity. Decrease in events is partially a pleiotropic effect. tandfonline.com/doi/full/10.10…
@NathanEqualsOne @MichaelMindrum You have to remember that there are a family of receptors...probably >1000 at last count 🤯
@MichaelMindrum @DrScottMurray Compensation due to defective LDLr? Isn’t the defect global, not liver specific?
@MichaelMindrum @NathanEqualsOne Its actually both LDL-r and LRP1 (receptor related protein) probably in various degrees. LRP1 hugely involved with coagulation cascade, factor VIII mainly but VWf too. I am sure there are knock on metabolic affects we dont know 😬. Its also affects vadcular wall Try this paper 👍
@MichaelMindrum @DrScottMurray LDLr problem -> possible cellular metabolism issues, macrophage issues. LDLr also takes up clotting factors, many with FH have abnormal clotting.
@MichaelMindrum @DrScottMurray The clotting factor clearance is probably also a plieotropic effect of PCSK9i
"Data suggest that EC with damaged LDLRs per se appear to be PREDISPOSED to DYSFUNCTION ,OXIDATIVE STRESS, & chronic INFLAMMATION,which,in combination with ⬆️ extrinsic LDLc,may accelerate ENDOTHELIAL DYSFUNCTION, contribute to athero & cause EARLY AND ACCELERATED FH PROGRESSION"
This. Again.
In #LMHR, saturated fat does not appear to be the major driver of high LDL-C 5 reasons: 1) Effect Magnitude (2 big 2🐝 🧈) 2) LMHR lipid ‘TRAID’ (not just LDL… metabolic “context”) 3) Inverse association between BMI and LDL-C on low-carb diets 4) LMHR with high LDL-C on…
@realDaveFeldman I think the post-hoc PESA subgroup analyses that did not specify its statistical methodology a priori needs to be redone using non-biased machine learning including c-peptide, ApoC-III on LDL, LPIR, and PRS in model but ya don’t see me complaining about it 🤪
I think you may be operating under the expectation I am unblinded to the data and/or can change the analysis as it is ongoing – which I do not, nor can't, respectively. (And appropriately so) I mentioned on your podcast both the pros and cons in both scenarios. But while we're…
This is a solid point @realDaveFeldman I think that analysis needs to be redone removing those on lipid lowering drugs from control.
Yes – @_earthling74 100% nails it here. "Work with your doctor" doesn't mean "all doctors are correct" nor is it a hand-wavey disclaimer that I don't actually believe which would then allow me to say anything, as some detractors claim. It's an acknowledgement that doctors serve…
@Tellit007 @burby_geek @theproof @realDaveFeldman @Lipoprotein @realDaveFeldman tells people to work with their doctors over and over and over. people hear what they want to hear. that’s the problem.
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