John E. Moses @HarborSpring
Professor of Organic & Click Chemistry at Cold Spring Harbor Laboratory, New York. Celebrating Chemistry for Biology at CSHL. Cold Spring Harbor, NY Joined October 2020-
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It was wonderful to catch up with past colleagues and friends, Professors Gerry Pattenden and Neil Oldham in Nottingham 🥂
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John E. Moses retweeted
The #PrimeView for #DiversityOrientedClicking explains how these multi-clickable hubs can be built and modified: 🧱🧪 nature.com/articles/s4358…
John E. Moses retweeted
Happy to share this week's #Primer from @HarborSpring (@CSHL) and team on #DiversityOrientedClicking! This synthesis technique uses click-chemistry hubs for designing molecular probes and new drugs. Check it out here 👇🧑🔬👨🔬👩🔬 nature.com/articles/s4358…
John E. Moses retweeted
John E. Moses retweeted
President George W. Bush and Ozzy Osbourne at the 2002 White House Correspondents Dinner
More good funding news! We’ve been awarded a NIH UG3 grant with the Tuveson Lab for a project combining click chemistry + natural products to block KLK6 and prevent early pancreatic cancer. Grateful to NIH and all collaborators pushing this forward.
John E. Moses retweeted
🧵[1/10] A busy week for K-Ras! We report three stories on covalent, mutant-selective targeting of oncogenic K-Ras mutations @ACSPublications. Covalent chemistry has been key in drugging this once “undruggable” GTPase. Sotorasib and adagrasib are the only approved therapeutics.
Grateful to the NCI for awarding us an R01 grant to support a collaborative project between my lab and David Tuveson’s lab at CSHL. The work focuses on precision targeting of pancreatic cancer using Clickable Covalent Metabolite Mimetics (CoMMs)—a new class of therapeutics.
John E. Moses retweeted
🎉 Our new paper on live, intracellular #ClickChemistry just posted in @NatureComms! Huge shoutout to lead author @KeqingN for all of the hard work 🙌🏼 Check it out 👉🏼 rdcu.be/enfHz
John E. Moses retweeted
Big congratulations to CSHL Professor John Moses (@HarborSpring ), newly elected Fellow of the Learned Society of Wales (@LSWalesCDdCymru)! A pioneer in click chemistry, Moses is advancing research on cancer, infections, and neurological disease—while honoring his roots.…
John E. Moses retweeted
Long Island lab discovers breakthrough against pancreatic cancer trib.al/G7sBf3S
John E. Moses retweeted
Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.
Congratulations to my fantastic team and collaborators on our SuFEx Click Chemistry paper being amoung the most popular Chem. Sci. articles in 2024 🥂👏 pubs.rsc.org/en/journals/ar…
John E. Moses retweeted
Keir Starmer mocked by Stephen Flynn MP.
John E. Moses retweeted
A postdoctoral position, funded by the @LeverhulmeTrust for up to 36 months, is available to join my group @EdinburghChem . The project focuses on biomimetic approaches to natural product synthesis. Deadline: 18th April 2025. elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…
Many thanks to the Leon and Betty Ajces Trust for generously funding of our work on Click Cancer Therapies 🥂
John E. Moses retweeted
Great news today about the award of our National Cancer Institute, NIH grant: Congratulations to the team 🥂🙏
John E. Moses retweeted
What began with frozen brain samples and an unexpected connection has become one of the most impactful discoveries in Parkinson’s research. Ellen Sidransky uncovered that a mutation in the GBA gene, typically associated with Gaucher disease, also significantly increases the risk…
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