Immunometabolism Forum (IMF@Global) @ImmunoMetForum
IMF@Global is a platform for early career researchers to present and discuss their ongoing projects in the field of immunometabolism @ImmunoMetEurope docs.google.com/forms/d/e/1FAI… Online via Zoom Joined June 2023-
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📣 Thrilled to be part of the lineup at the upcoming #pint24 Ireland! Looking forward to talking about Immunometabolism 🤩 and having a pint (or 2) 🍻 Join us! Tickets are free 👇🏼 🗓 May 15th @ 7pm 📍Newtown Inn Sports Bar, Maynooth @pintofscienceIE pintofscience.ie/event/maynooth…
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis: Cell cell.com/cell/fulltext/…
Thank you to our 3 great presenters, @NimuMacharia, @RyanLab_MBU and @MrJamieSugrue, at today’s @ImmunoMetForum meeting. #immunometabolism #macrophages #cholesterol #mitochondria #SteroidHormones
Second up at this month’s @ImmunoMetForum will be @RyanLab_MBU, a new PI at @Cambridge_Uni. Dylan did his PhD @tcdbi with @laoneill111, so no stranger to the IMF. #mitochondria #macrophages #immunometabolism
This month’s @ImmunoMetForum takes place this Friday. Our first presenter will be @NimuMacharia from @LucyHJackson_J lab from @LancasterUni. #Cholesterol #Macrophages #Immunometabolism
Prof. Tamara Boto @TamaraBoto & I are looking for a PhD student to join us to investigate BBB dysfunction in repetitive mTBI🧠 This is part of a new @tcddublin PhD training programme on sports related concussion with @mattcampbelltcd @SDoyleTcd @gastaut @NollaigBourke Info👇
Our lab at Princeton University and Ludwig Cancer Research Institute, Princeton Branch, is hiring a Research Specialist, to study the effects of diet and obesity on immunometabolism and cancer, ideally with experience as below. ludwigcancer.princeton.edu/opportunities/…
Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer | Science Advances science.org/doi/10.1126/sc…
rdcu.be/dBUD3 and rdcu.be/dBUz8 Two interesting papers on metformin's action to elevate circulating Lac-Phe. Non-specific product of anaerobic metabolism or physiological mediator of appetite? The jury is still out I would say. I cant find any mention/
@StephenORahilly All fair points Stephen. I think it will be interesting to see where this Lac-Phe story leads. @BazFScott also showed that Lac-Phe levels increase after eating a meal.
Scientists from @tcdTBSI and @longlabstanford have uncovered new secrets to natural appetite control, offering promise in the battle against #obesity and #type2diabetes. Read more about this important #TrinityResearch at: tcd.ie/news_events/ar…
Proud to be part of this groundbreaking #TrinityResearch on appetite control. A step closer in our fight against obesity and diabetes. 🧬🔬🍏 #Obesity #Type2Diabetes
Proud to be part of this groundbreaking #TrinityResearch on appetite control. A step closer in our fight against obesity and diabetes. 🧬🔬🍏 #Obesity #Type2Diabetes
Back-to-back papers in @NatMetabolism today: a surprising connection between the appetite-suppressing metabolite Lac-Phe and metformin-associated weight loss. From @lynchielydia and @skxiao_nju @Stanford_ChEMH nature.com/articles/s4225… nature.com/articles/s4225…
@DavidFinlayTCD @lynchielydia @longlabstanford I hopped on my bike 🚴 to communicate our Lac-Phe study to a wider audience. Sadly, it’s still incomplete - deadlines won 😅!
Thrilled to see both Lac-Phe studies published back-to-back—and to have my first paper among them! 🌟 A heartfelt thanks to @DavidFinlayTCD and @lynchielydia for their guidance, and kudos to the entire team at the @longlabstanford!
Thrilled to see both Lac-Phe studies published back-to-back—and to have my first paper among them! 🌟 A heartfelt thanks to @DavidFinlayTCD and @lynchielydia for their guidance, and kudos to the entire team at the @longlabstanford!
@lynchielydia @longlabstanford @NatMetabolism nature.com/articles/s4225… Nice news and views article in @NatMetabolism on this recent work linking metformin to Lac-Phe and appetite suppression.
Work from the Long Lab @longlabstanford and our lab working with @DavidFinlayTCD on links between metformin, and eating (especially solid food) on Lac-Phe levels and appetite suppression @NatMetabolism
Work from the Long Lab @longlabstanford and our lab working with @DavidFinlayTCD on links between metformin, and eating (especially solid food) on Lac-Phe levels and appetite suppression @NatMetabolism
Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer: Cell cell.com/cell/fulltext/…
Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment: Cell Metabolism cell.com/cell-metabolis…
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Lynne Faherty @lynne_faherty
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Fábio L Orsatti, PhD @fabiorsatti
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stephen o'rahilly (it.. @StephenORahilly
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Barry Scott @BazFScott
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Jennifer Dowling @DowlingJK83
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ImmunoMetNet @ImmunoMetNet
1K Followers 0 Following Come ImmunoMet-Networking at one of our local or (inter)national meetings. https://t.co/X1hCX27HIB for more info An initiative of @immunometlab and friends...
Kaechlab (Sue Kaech) @Tcellogic
5K Followers 282 Following Scientist. Optimist. Mom. Champion of long-term immunity. “You must do the things you think you cannot do.” -Eleanor Roosevelt
Swagato Bhattacharjee @Swagato_Bio
41 Followers 3K Following Junior Scientist @kosh_key ~ @Jamora_lab | Postgraduate @RGCB_Trivandrum '23 | SXC Microbiology '21 |
Stefanie Wculek @SWculek
736 Followers 351 Following *Innate* immunologist - Dendritic cells, neutrophils, macrophages and their metabolism Junior Group Leader @IRBBarcelona
Anna Ledwith @LedwithAnna
127 Followers 337 Following Immunology PhD student at Trinity College Dublin | interested in obesity and cancer immunology
Calum Bain @bainlab
2K Followers 492 Following Immunologist at University of Edinburgh Centre for Inflammation Research. My lab studies the biology of monocytes, macrophages and DCs in health & disease
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832 Followers 1K Following Immunologist. Assistant Professor @WCMpeds. Passionate about inspiring others to pursue STEM. Movie buff. Food lover. Photography enthusiast. she/her
Ruairi Robertson @ruairirobertson
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Dr Lucy Jackson-Jones @LucyHJackson_J
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Tara Steffen @ImmunityTara
120 Followers 430 Following #firstgen PhD. Postdoc at Saint Louis University School of Medicine👩🏻🔬 Immunometabolism 🧪Mediocre rock climber 🧗🏻Ambassador for @biorender
Cassie Clarke @CassieJClarke
502 Followers 422 Following Associate Scientist @CRUK_SI / Prevention / Early Detection / Metastasis / Metabolism / Translation / Tumour Microenvironment / Women in STEM / Views are my own
Dearbhla Murphy @derv_murphy
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110 Followers 108 Following Official Twitter account of the Acting Chief, Cancer Innovation Laboratory, CCR, NCI. Privacy: https://t.co/R4Q5YoZsh7📣 Thrilled to be part of the lineup at the upcoming #pint24 Ireland! Looking forward to talking about Immunometabolism 🤩 and having a pint (or 2) 🍻 Join us! Tickets are free 👇🏼 🗓 May 15th @ 7pm 📍Newtown Inn Sports Bar, Maynooth @pintofscienceIE pintofscience.ie/event/maynooth…
Thank you for hosting @DavidFinlayTCD and really enjoyed the other talks and the great questions! Fantastic forum to share developments in #immunometabolism
Thank you to our 3 great presenters, @NimuMacharia, @RyanLab_MBU and @MrJamieSugrue, at today’s @ImmunoMetForum meeting. #immunometabolism #macrophages #cholesterol #mitochondria #SteroidHormones
@BSI_immunomet @lynchielydia @ImmunoMetForum @LindaVSinclair @MPI_Metabolism @ImmunoMetlab @Immetab_asi @ImmunoMetNet @ImmunoMet @PCHo_Lab @SarahDimeloeLab Looking forward to catching up with all you Immunometabolism aficionados in Newcastle! @DrSianH @SpLAB_KCL
@StephenORahilly @DavidFinlayTCD @BazFScott ...and these situations (exercise, metformin, sold meal but not liquid) are associated with appetite suppression, which is not induced by lactate alone. So the Lac-aa could be playing a role here, not sure yet if Lac-Phe is particularly involved compared to the others
@StephenORahilly @DavidFinlayTCD @BazFScott Yes data from @BazFScott definitely looks like other lactolated aa increase at the same time, and their levels strongly correlate with Lac-Phe. Thoughts are that anything that increases lactate (metformin, exercise, eating solid meal) can induce Lac-Phe and other Lac-aa....
We've known for >50 years that metformin markedly increases cellular lactate production. We now know that cells pour out a bunch of different amino acids conjugated to lactate in response. Non-specific or not? Some key experiments are still missing. I'll wait with interest.
@StephenORahilly All fair points Stephen. I think it will be interesting to see where this Lac-Phe story leads. @BazFScott also showed that Lac-Phe levels increase after eating a meal.
@BazFScott @DavidFinlayTCD @lynchielydia @longlabstanford This is wonderful stuff, Barry - you HAVE to finish it…
@ClionaOfarrelly @DavidFinlayTCD @lynchielydia @longlabstanford Thanks, Cliona! You're right, it would be a shame to leave it hanging 🤔
Scientists from @tcdTBSI and @longlabstanford have uncovered new secrets to natural appetite control, offering promise in the battle against #obesity and #type2diabetes. Read more about this important #TrinityResearch at: tcd.ie/news_events/ar…
Proud to be part of this groundbreaking #TrinityResearch on appetite control. A step closer in our fight against obesity and diabetes. 🧬🔬🍏 #Obesity #Type2Diabetes
Scientists from @tcdTBSI and @longlabstanford have uncovered new secrets to natural appetite control, offering promise in the battle against #obesity and #type2diabetes. Read more about this important #TrinityResearch at: tcd.ie/news_events/ar…
The second speaker at Fridays @ImmunoMetForum is Erica Brown from @RoddyOConnor lab at @Penn. #Tcells #Immunometabolism #Cancer linkedin.com/in/erica-g-bro…
Our @ImmunoMetForum returns on Friday and our first speaker is @grainnejameson from @ShareeBasdeo lab in @TCDTMI who works on a cell type close to my heart 😀❤️ #NKcells #Immunometabolism
Frustrated by the difficulties of measuring metabolism of rare immune subsets? 🤬 Perplexed about how to avoid metabolic artifacts after putting your cells in culture? Help is at hand------- Thread 🧵1/12
It’s all about lactate these days 😁. Another interesting Lactate paper. Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade doi.org/10.1016/j.immu… #immunometabolism #lactate #Tregs
Recruiting for an Assistant Professor position here at the School of Biochemistry and Immunology @tcdbi in @tcdTBSI Dublin: tinyurl.com/BIAssProf I started my lab here in 2011 and has been a great place to do science 👨🔬🔬🧬 #Biochemistry #Immunometabolism RTs appreciated 😀
Gave up my parking at work #pedalpower from here on out (ok, there will be an occasional Uber)
Nice study that defines an important role for ASCT2 (SLS1A5) as a serine transporter in cancer. And we have a single cell assay for that. Must check whether serine competes for uptake of the click-AA in this assay in immune cells. I'll keep you posted 😁 doi.org/10.1016/j.celr…
Serine metabolism in cancer is well-understood and appreciated, but the identity of serine transporters has been a missing piece of the puzzle for too long...Check out my new preprint to find out more! 🧵 Thank you to the entire @ColoffLab for this one! biorxiv.org/content/10.110…
This is the best educational collection put together in recent years for those who want to embark on a scientific life. I wish we had such a detailed source when we started our scientific career and were trying to write our first articles. lnkd.in/eZRVgXRu
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