Dylan Ryan @RyanLab_MBU
Group leader at MRC mitochondrial biology unit (MBU), University of Cambridge. An immunometabolism enthusiast. 🦋 @ryanlab.bsky.social mrc-mbu.cam.ac.uk/research-group… University of Cambridge Joined August 2021-
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And thus, TRANSLONOMICS was born!
Dylan Ryan retweeted
A common type of ant in Europe breaks a fundamental rule in biology: its queens can produce male offspring that are a whole different species go.nature.com/3JIU9yM
Dylan Ryan retweeted
#MycobiotaPower! Exciting work @Nature by Behnsen, Jaswal &co showing that #Salmonella uses type 3 secretion system to hijack #Candida_albicans to produce arginine in the gut, boosting Salmonella infectivity & reducing the immune response! nature.com/articles/s4158…
Big personal news. I'm proud to announce I've returned home to Ireland to start a tenure track Assistant Professorship in the School of Biochemistry and Immunology @tcdTBSI @tcddublin today. Back to where my love for #immunometabolism started, an exciting new career chapter!
Dylan Ryan retweeted
Unlocking longevity through the comparative biology of aging nature.com/articles/s4358…
Dylan Ryan retweeted
Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling? embopress.org/doi/full/10.10…
Dylan Ryan retweeted
Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function nature.com/articles/s4146…
Protein(s): IRG1/ACOD1 + TCA cycle enzymes Function: Anti-microbial activity & immunomodulation. Behaviour: Release of mitochondrial nucleic acids (DAMPs) during infection, which synergise with PAMPs to regulate innate immune response. #Immunometabolism #mitochondria
Protein(s): IRG1/ACOD1 + TCA cycle enzymes Function: Anti-microbial activity & immunomodulation. Behaviour: Release of mitochondrial nucleic acids (DAMPs) during infection, which synergise with PAMPs to regulate innate immune response. #Immunometabolism #mitochondria
Dylan Ryan retweeted
🤍💚 When I first started studying mitochondria, I saw them mainly as ancient endosymbionts - keepers of oxidative phosphorylation, the TCA cycle, and population history through mtDNA. But the deeper I went, the more I realized: mitochondria are everywhere in cell biology.
Evidence that mitochondria in macrophages are destroyed by microautophagy #mitochondria nature.com/articles/s4146…
Dylan Ryan retweeted
Nature research paper: Haematopoietic stem cell number is not solely defined by niche availability go.nature.com/45OVkE8
Dylan Ryan retweeted
A structured prehabilitation program may be a safe and effective strategy to improve surgical outcomes in high-risk patients with sarcopenia who are undergoing major liver surgery. ja.ma/4lOo2Ll
Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques ahajournals.org/doi/10.1161/JA…
Dylan Ryan retweeted
🚨 RFK Jr just claimed he can spot kids “with mitochondrial dysfunction” walking through airports. No—you can’t diagnose complex metabolic disorders by sight. Here’s why this is dangerous nonsense.
Dylan Ryan retweeted
New! Online now: Homocysitaconate controls inflammation through reshaping methionine metabolism and N-homocysteinylation dlvr.it/TMk106
Dylan Ryan retweeted
Mitochondrial transfer go.nature.com/3UK9jpJ
Dylan Ryan retweeted
Mitochondrial activity tunes nociceptor resilience to excitotoxicity cell.com/cell/fulltext/…
Dylan Ryan retweeted
Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism dlvr.it/TMj8BT
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