RehlingLab @RehlingLab
Department of Cellular Biochemistry University Medical Center Goettingen and @mpi_nat. We study mitochondrial biogenesis in health and disease biochemie.uni-goettingen.de/index.php?id=2… Goettingen, Germany Joined May 2021-
Tweets339
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Followers1K
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Following202
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My paper is out in @ScienceMagazine! We found a novel host defense strategy where #mitochondria, our domesticated microbes, compete with the intracellular pathogen #Toxoplasma for #folate. science.org/doi/10.1126/sc…
New in @ScienceMagazine with a related Perspective Mitochondria protect against an intracellular pathogen by restricting access to folate | Science science.org/doi/10.1126/sc…
Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc…
Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc… - Now available in new Science issue. Thanks again to all colleagues for a wonderful collaboration. Awesome work of LD Cruz-Zaragoza!
Online Now: Structural basis for promoter recognition and transcription factor binding and release in human mitochondria dlvr.it/TM5SKN
Ein starkes Signal für Wissenschaft und Innovation! Vielen Dank an den Freistaat Bayern, @Markus_Soeder und @MarkusBlume für die Unterstützung beim Ausbau der #Spitzenforschung und der Life-Sciences in Bayern.
Ein starkes Signal für Wissenschaft und Innovation! Vielen Dank an den Freistaat Bayern, @Markus_Soeder und @MarkusBlume für die Unterstützung beim Ausbau der #Spitzenforschung und der Life-Sciences in Bayern.
Our story about FASTKD5 is now published at @NAR_Open. It was an amazing collaboration with @hauke_hillen and @Antonio41949078 labs. doi.org/10.1093/nar/gk… FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
Interaction with AK2A links AIFM1 to cellular energy metabolism dlvr.it/TLlYRd
Our study on how mitochondrial methylation shapes gene expression is now out. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Read all about it at: rdcu.be/etk12
Our study on how mitochondrial methylation shapes gene expression is now out. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Read all about it at: rdcu.be/etk12
Online now - Discussing the future of mitochondrial biochemistry dlvr.it/TLWD7C
SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart: Cell Reports cell.com/cell-reports/f…. Great collaboration with @niels_voigt, @CZphenogenomics, D. Katschinski, & H. Urlaub. Thanks to Angela Boshnakovska, Laura Kremer and our lab!
Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc…. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, @warscheidlab & @JakobsLab .
Great collaboration with @hauke_hillen and @RehlingLab. Thank you very much to everyone involved.
If you’re curious about the intricate control of human mitochondrial translation, take a look at our latest review - just out!
If you’re curious about the intricate control of human mitochondrial translation, take a look at our latest review - just out!
Understanding mitochondrial protein import: a revised model of the presequence translocase: Trends in Biochemical Sciences cell.com/trends/biochem…. New review, describing current advances regarding the TIM23 complex. Great work by Naintara Jain together with Agnieszka Chacinska.
In situ architecture of the human prohibitin complex nature.com/articles/s4155…
We recruit leaders on different stages and offer unique atmosphere of a vibrant an open research community. Strenghtening interdyscyplinarity is well seen! Also for: - Scientists with commercialization interests and/or targeted projects !!! - US based scientists !!!
We recruit leaders on different stages and offer unique atmosphere of a vibrant an open research community. Strenghtening interdyscyplinarity is well seen! Also for: - Scientists with commercialization interests and/or targeted projects !!! - US based scientists !!!
A microscopy-based screen identifies cellular kinases modulating mitochondrial translation: Cell Reports cell.com/cell-reports/f…. a great end of the year. Thanks to our collaborators @RDennerlein_Lab, @RizzoliSilvio @DavidPacheu and Henning Urlaub
Valenti, David, Schuldiner et al. @WeizmannScience created a proteome-wide yeast degron library for rapid in vivo protein depletion. This tool enables dynamic protein function studies with minimal cellular rewiring, advancing beyond prior collections. hubs.la/Q0302VkW0

FrezzaLab @FrezzaLab
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Hauke Hillen @hauke_hillen
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JakobsLab @JakobsLab
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Rutter Lab @RutterLab
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Cell Reports @CellReports
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DFG public | @dfg_pub... @dfg_public
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