WredenbergLab @WredenbergLab
Mitochondrial research at the Division for Molecular Metabolism, Karolinska Institute @wredenberglab.bsky.social wredenberglab.com Stockholm, Sweden Joined August 2020-
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Our study on how mitochondrial methylation shapes gene expression is now out. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Read all about it at: rdcu.be/etk12
Our study on how mitochondrial methylation shapes gene expression is now out. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Read all about it at: rdcu.be/etk12
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. academic.oup.com/nar/article-ab…
New paper out from the Falkenberg and Gustafsson labs. Thanks to Pretzel for a successful collaboration. nature.com/articles/s4158…
Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our group in Stockholm. @mitojobs @MolMet_KI For the PhD position: kidoktorand.varbi.com/what:job/jobID… For the PostDoc position: ki.varbi.com/what:job/jobID…
Check out our recent paper showing how maternal inheritance of mtDNA is guaranteed in D. melanogaster.
Check out our recent paper showing how maternal inheritance of mtDNA is guaranteed in D. melanogaster.
I'm excited to share our latest work linking TAG mobilization to mitochondrial stress recovery. A monumental effort by @Zak_Bakes (on the faculty job market soon!). Great collaboration with the @Coon_Labs and others. rdcu.be/d5ACF #mitochondria #HHMINews
The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the reviewers for their constructive comments! nature.com/articles/s4159… See also the very nice related work by @BMartinHallberg @no1gv: embopress.org/doi/full/10.10…
The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the reviewers for their constructive comments! nature.com/articles/s4159… See also the very nice related work by @BMartinHallberg @no1gv: embopress.org/doi/full/10.10…
New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice! academic.oup.com/nar/article/do… #RNA #mitochondria #mtDNA
Just over a week left to apply for a PostDoc position in mitochondrial biology with us. #mitochondria @mitojobs ki.varbi.com/ny/what:job/jo…
We have 1-2 PostDoc positions for enthusiastic researchers interested in mitochondrial biology. Apply here. #mitochondria #mitojobs ki.varbi.com/ny/what:job/jo…
Extremely proud to share our integrative work on how 'Dissected antiporter modules establish the minimal proton-conducting elements in Complex I' – now out in Nature Comms! Many thanks to @KAWstiftelsen & @Vetenskapsradetfor funding. nature.com/articles/s4146…
🚨Mitochondrial research out🚨 Our latest work on the synergy between LRPPRC and SLIRP for maintaining mtDNA gene expression in vivo is now published! 🧬 Free-access link to the article: academic.oup.com/nar/article/52…
Happy to share our latest manuscript on using quantitative proteomics to diagnose patients with mitochondrial disease. Great collaboration with @taylorlabncl and @lukas_k insight.jci.org/articles/view/…
We are excited to share our lab's first preprint, highlighting the role of the CHCHD2-CHCHD10 complex in preserving tissue homeostasis. A huge thank you to all our collaborators! biorxiv.org/content/10.110…

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