Jacob @Jacob_sci
Walter-Benjamin PostDoc Fellow👨🏼🔬 RNA-Biologist 🧫 Cancer Researcher🧬 at Filbin Lab | @DanaFarber | @HarvardMed | @BroadInstitute Boston, MA, USA Joined July 2020-
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What a great manuscript from Jakob Trendel @kusterlab ! After XRNAX (loved it!) XDNAX helps enriching for DNA-associated proteins! Top quality paper
What a great manuscript from Jakob Trendel @kusterlab ! After XRNAX (loved it!) XDNAX helps enriching for DNA-associated proteins! Top quality paper
Excited to share a study just published in @ScienceAdvances led by @Edwardg95508954 @DKFZImmunology @Platten_lab @DKFZ and John Lindner @BioMed_X and the incredibly talented Tamara Boschert. science.org/doi/10.1126/sc…
Landmark paper alert! Women develop more autoimmune disease -> The proteins associated with the long non-coding RNA Xist (silence the second X chromosome in women) comprise numerous autoantigenic components as important driver of sex-biased autoimmunity cell.com/cell/fulltext/…
Promoter, Enhancer, Super-Enhancer- and here comes the Coordinator! Exciting read! Out in Cell cell.com/cell/fulltext/…
Published today! 📰 @NatureMedicine One of the first #cancer vaccines💉that target #KRAS. Not just G12C. 👇🏾The 2-peptide was G12D & R. The 7-Peptide/Elicio targets D R V S A C G13 ➕ NRAS Implications for so many patients! Open now. Cheers! @OncoAlert nature.com/articles/s4159…
Finally out! We found that mRNAs are not uniformly distributed across the cytoplasm. mRNA architecture is the strongest determinant for localization. Subcytoplasmic location of translation controls protein output. cell.com/molecular-cell…
Rocket science is hard. Designing systems capable of launching materials—including humans—into orbit and then smoothly landing back on terrestrial ground is one of the greatest feats of engineering we’ve achieved. But surviving in space will be even harder. In his brilliant…
First trial of ‘base editing’ in humans lowers cholesterol — but raises safety concerns go.nature.com/47ekkUM
Finally out! 👨🏼🔬 We describe non-telomeric effects of Tert upregulation in thyroid cancers in mice with the very first model containing a Tert promoter mutation. What a journey for this story and Iñigo. 🍻
Finally out! 👨🏼🔬 We describe non-telomeric effects of Tert upregulation in thyroid cancers in mice with the very first model containing a Tert promoter mutation. What a journey for this story and Iñigo. 🍻
Very excited to see our study on a case of ALL to AML switch after CAR-T treatment out in @NatureCancer! Using deep genome sequencing, we show the cancer switched cell types to escape therapy. @broadinstitute @sangerinstitute @getz_lab Thread below 🧵 nature.com/articles/s4301…
We’re excited to share our preprint on spatial organization in glioblastoma: doi.org/10.1101/2023.0…. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal a five-layer organization of cellular states and highlight a role of hypoxia as tissue organizer. 1/
Out today in @NatureGenet, our work utilizing single-cell multi-omics to define specific immune cell subsets that experience purifying selection against pathogenic mitochondrial DNA. nature.com/articles/s4158… Check out a thread about this work below: 1/22
Registration is now open for the Berlin Summer Meeting 2023 - The MDC Celebrates 15 Years of BIMSB, 6-7 Sept, 2023: bit.ly/bimsb2023 We are looking forward to a fantastic line-up showcasing exciting new developments in #systemsbiology @MDC_Berlin
Cracking the "black box” using human brain organoids, truly inspiring discoveries ahead of us! 🧫🧠🧬#brainorganoids #organoids #stemcells #future #development
Cracking the "black box” using human brain organoids, truly inspiring discoveries ahead of us! 🧫🧠🧬#brainorganoids #organoids #stemcells #future #development
There is an open position available in the Landa lab! Collaborate with clinicians/researchers in the Boston/Harvard environment! Help advancing the knowledge on advanced thyroid cancers and join a leading lab in the field. #thyroid #brighamandwomens #harvardmed #boston
There is an open position available in the Landa lab! Collaborate with clinicians/researchers in the Boston/Harvard environment! Help advancing the knowledge on advanced thyroid cancers and join a leading lab in the field. #thyroid #brighamandwomens #harvardmed #boston
Single-cell ATAC-seq finds active regulatory elements across cell types, but its resolution can be limited. What if we could identify when and where proteins bind to chromatin? Introducing PRINT, a new single-cell footprinting tool from @JD_Buenrostro lab biorxiv.org/content/10.110…
I'm thrilled to share our new study reporting why DNA replication timing is important for the formation of oncogenic translocations, now published in @ScienceMagazine. In the Pavri lab, we explored oncogenic translocations in #lymphoma & #leukaemia 🧵👇 1/ doi.org/10.1126/scienc…
An extremely interesting case report about thyroid cancer with platinum signature occurring 8 years after previous platinum-based chemotherapy of ovarian cancer☝🏻Nice job Theodora and the other authors ascopubs.org/doi/figure/10.…
Join our lab in Boston! You‘ll have the chance to experience great science, collaborations and Iñigo as the best PI.👨🏼🔬 #thyroidcancer #research #sciencejobs #boston
Join our lab in Boston! You‘ll have the chance to experience great science, collaborations and Iñigo as the best PI.👨🏼🔬 #thyroidcancer #research #sciencejobs #boston
Looking for protein chemists to join my lab @KidsCancerInst. If you are interested (more details) please DM. Exciting opportunity to develop tools to study RNA-protein interactions in cancer.
Talisa Raiche @RaicTali
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236 Followers 543 Following An Enthusiastic Brazilian Scientist fighting for a greater good. Postdoc at Dana-Farber Cancer Institute/HMS and Co-founder of NEOGENYS Molecular Diagnostics.
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Nick Gray / How to Ma.. @nickgraynews
42K Followers 3K Following Follow me to be more interesting and meet inspiring people 👋🏻 I built and sold 2 multi-million dollar companies, Museum Hack and FDS Avionics
Vic 🌮 @VicVijayakumar
19K Followers 3K Following 3x dad, 6.2x runner, 0.5x violinist, 1x principal eng @twilio. Building @everyoak @mailtimer @engadvicepod. I talk about SaaS, databases, HOAs, & eggs.
American Academy of A.. @americanacad
18K Followers 1K Following Honoring excellence and leadership. Working across disciplines and divides. Advancing the common good. From 1780 to today. RTs ≠ endorsements.
Sebastian Steudtner @SebastianSurfs
1K Followers 75 Following 🌊 Big Wave Surfer 🏆 3x Big Wave Award Winner & World record holder My dream is to surf the biggest waves on this planet and to be the best I can be. 🤟🏻
Jelani Clarke, PhD (�.. @JelaniC3
1K Followers 658 Following Neuroimmunologist👨🏽🔬 championing (De)centralized (Sci)ence #DeSci. Core @Desciworld 🌐| Founder @DeSciMTL| CBDO @Amino_Chain 🇨🇦🇧🇧🇯🇲
DoctorDueDiligence @DueDoctor
2K Followers 212 Following Pro 🇺🇸| Policy |Biotech Memes+Parody |Deeply Curious about Macro Biotech Landscape |All opinions are my own|Not Investment Advice | Health Conscious & Love 🌳
ResearchHub Peer Revi.. @RHF_Alerts
291 Followers 2 Following Tired of doing peer-reviews for free? We value your expertise. Get $150 per review. Follow us to stay up to date on @researchhub bounties and peer reviews.
ResearchHub Foundatio.. @ResearchHubF
2K Followers 2 Following Official Twitter profile of the ResearchHub Foundation and home of the ResearchHub Community governed by $RSC | Supporting @researchhub
Jeffrey Koury @jeffyfish9
524 Followers 401 Following Director at @ResearchhubF | PhD Biomedical Science @UCRiverside | All opinions my own
Prime Intellect @PrimeIntellect
9K Followers 301 Following Find compute. Train models. Co-own intelligence. https://t.co/3NC0duKF4a.
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121K Followers 228 Following "The Anti-Fragile Investor" | I demystify the stock market | My portfolio: https://t.co/Y4ueSL9uly
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19 Followers 86 Following Research Intern in Filbin Lab @DanaFarber | Pediatric Neurooncology | MSc student Biomedical Sciences @UniUtrecht
ResearchHub @ResearchHub
14K Followers 1 Following A modern day preprint server that incentivizes the open publication of transparent research. Let's accelerate science!
Andrew M Wade @seavixen899
7K Followers 3K Following A Fleet Air Arm veteran trying to make sense of this mad world. Huge respect to our Armed Forces. Never left, always right. Long time Peterborough United fan.
Dana-Farber News @DanaFarberNews
5K Followers 385 Following Your official source for @DanaFarber Cancer Institute news | Research, science, and innovation | Media requests: [email protected] or 617-632-4090
Steve · Millionaire .. @SteveOnSpeed
323K Followers 89 Following Money, Confidence and Strength || Mission: Help 10M people achieve financial freedom || Learn how to steal the habits of millionaires in my free newsletter
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5K Followers 205 Following Former burned-out attorney now savoring life one mini-retirement at a time. Experienced 4 (month-long+) mini-retirements since 2018.
mallory (she/her)💬 @this_is_mallory
30K Followers 1K Following hi, I’m mallory 🙋🏻♀️ let’s talk about misinformation, the ✨Wellness✨ industry, influencers, and MLMs | views are my own
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366K Followers 352 Following 🏰 Quality Stocks 🧑💼 Former Professional Investor ➡️ Teaching people about investing on our website.
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25K Followers 91 Following Building my 4th 8-figure biz (B2B media holdco). Also GP & Investor at The Family Fund VC. Biomed engineer too. Helping founders achieve breakout performance.
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67K Followers 16K Following I help professors, postdocs, and other overworked, underappreciated PhDs change careers without sacrificing what's important. Start for free https://t.co/t6LqWmaLdq
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Nick Huber @sweatystartup
365K Followers 3K Following Sold a service company for 7 figures. Now a self storage operator with 1.9 million square feet and 44 employees. I send a weekly email to 240K people. Athens GA
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MadScientist @MadS100tist
14K Followers 5K Following Neuro and Developmental biologist. PostDoc at day. Supervillain at night. #BlackLivesMatter #TransRightsAreHumanRights mads100tist in Mastodon and the sky app
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12K Followers 2K Following Funding & tokenization platform for biopharma IP. Fund research & participate in translation science from the earliest stages. https://t.co/zUPd1EUQ13
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23K Followers 2K Following d’Arbeloff Asst Prof @MIT • Neuromuscular Tissue Engineering for Medicine & Robotics • Women in STEM • 🇺🇸 via 🇮🇳 🇰🇪
Ludwig Cancer @Ludwig_Cancer
5K Followers 673 Following We fund cutting-edge scientific research across multiple Branches and Centers to better understand cancer and eliminate the suffering caused by the disease.
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514 Followers 447 Following Experimental population and community ecologist, focusing on effects of #globalchange on #demography and #biodiversity. Postdoc @UFZ_de and @iDiv.
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I am proud of every single paper that has come out of my lab, but this one feels truly special. This time, we asked: How to build a gliding mammal? Led by the stellar @JorgeMorenoPhD, I am happy to share our latest work, out in @Nature nature.com/articles/s4158… Please see 🧵👇
So thrilled about amazing @DaeunJeong10 defending her thesis successfully yesterday! First graduate student out of my lab, and especially meaningful with my own mentor @RosalindSegal as head of the committee: #proudmentor #gratefulmentee
Excited to share our new paper in @CellCellPress on spatial organization in glioblastoma authors.elsevier.com/c/1izT9L7PXqQI9. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal five-layer organization of cellular states and a role of hypoxia as tissue organizer. 1/
Recently Health Checking Urinals have begun popping up in Men's restrooms all over Shanghai. A private company is offering the urine analysis for RMB 20. Naturally I tried that out. Here's how that went.
There are fungi at Chernobyl that EAT radiation and nuclear fallout – and that’s only the start of this wild story 🍄☢️ Buckle up for a wild thread about radioactive boars, fungal space suits, radiation-detecting fungi, black frogs and a good dose of hope! 🧵
Accelerating science ⤴️🧬
And it's done. All three research projects fully funded in 7 days.👏
I'm going to start a new hashtag to show cases where universities or journals have been notified of severe (image) concerns years ago, but have not taken any action. I will name and shame, because it's frustrating and maddening. #IntegrityInertia
why is it called a nanodrop if the drop measured is a microliter
A new Science study suggests that preventing the mechanical damage caused by an asthma attack, rather than treating only its downstream symptoms, could pave the way for therapies that stop the whole asthma inflammatory cycle. 📄: scim.ag/6xn; scim.ag/6xm
This time last week, on Saturday morning, you woke up in your bedroom, were carried downstairs, ate very little breakfast and went back to sleep on the sofa. We knew something had changed. You slept for hours.
I highly recommend anyone working with single-cell data read this and take these issues seriously. These tools are under active development, which is terrific and to be applauded, but has also created a very fractured methods ecosystem. 1/
The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In biorxiv.org/content/10.110… w/ @Josephmrich et al. we take a close look. The results are 👀 1/🧵
Since the seasonal dunking-on-lncRNAs is back, and I do 💕 lncRNAs, a 🧵 on what I think have been the sources of the main problems in the 15 years of the field so far:
#UniteToFight2024 On May 15th - 16th, an international online #LongCovid & #MECFS Conference will take place, featuring over 18 hours of world-class speakers. The conference offers free access and is entirely community-driven. Please assist us in spreading the word about this…
5 years ago, I made a coffee table book with the world’s largest (known) prime number: 2^82589933 - 1 It usually sells a 1-2 copies a month, so when I went to get my 1099-MISC form from Amazon this year (#taxes), I was shocked to see it doing numbers… 🧵🕵️
Just in time for #HumpDay: Our study Targeting DCAF5 suppresses #SMARCB1-mutant #cancer via stabilizing SWI/SNF is online now in @Nature. Congratulations 🎉 to co-first authors Sandi-Radko-Juettner and @HongYue88665668 and all co-authors on this story! 1/ nature.com/articles/s4158…
Hey, @RITtigers I’m preeetty, preeetty sure that’s NOT how you hold a micropipette… Next time, please ask your Comms Dept to get input from your wonderful scientists - we are picky about the weirdest stuff 😊 (seen at @MBTA)
Join us on Thurs, April 25 for what will be an unforgettable day full of engaging speaker talks, a lively poster session and the unveiling of our first Lifetime Achievement Award. Register now for our 10th anniversary #RNA Medicine Symposium! bit.ly/48CFa0F
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Our talented scientists at the 2024 Scientific Retreat reflected on the greatest benefit of being a part of the DSA Community. @FilbinMariella, a DSA 2019 grantee, highlights the family-like bond of this community and the transformative impact that can have on her research.
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