Sethi_Lab @LabSethi
Dedicated physicians & scientists determined to improve outcomes in patients with gastrointestinal cancers through basic and translational research @DanaFarber sethilab.dana-farber.org Boston, MA Joined November 2020-
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Targeting CRC Plasticity! Dr. @Nilay_Sethi (@DanaFarber) shares work on endogenous reporter systems, revealing that HDAC1/2 inhibition promotes differentiation in colorectal cancer, thereby tackling therapy resistance. #DAVAGI #ColorectalCancer #GIOnc
Starting Now: Targeting RAS/RAF Moderated by: @Nilay_Sethi @DanaFarber #DAVAGI
One mother for two species via obligate cross-species cloning in ants | Nature nature.com/articles/s4158…
Please join us in congratulating HHMI Investigators Jennifer Doudna and David R. Liu (@davidrliu), recipients of national awards from the American Chemical Society (@AmerChemSociety) for 2026. 🔗cen.acs.org/people/awards/…
Looking forward to it! #CGAIGC25
I’m thrilled to be joining the @TheJimmyFund Radio-Telethon at 10am today, where I will be talking about all of the great #LynchSyndrome research and care performed here at @DanaFarber Donate to help strike out cancer: jimmyfund.gives/guest #KCANCER Tune in at 10!
Join us for The Science of Childhood Cancer lecture series hosted by @StJudeResearch this Thursday, August 14 at 12 CT/1pm ET where Bill will be presenting The Von Hippel-Lindau tumor suppressor: insights into oxygen sensing, tumor immunity, and drugging the undruggable.
A great collaboration with my friend @JunQiLab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.
A great collaboration with my friend @JunQiLab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.
We are looking for an associate research scientist and lab manager for our translational cancer immunology lab at Yale. Please email ([email protected]) or DM me to apply. Full information about the job and the requirements can be found here: jobrxiv.org/job/yale-schoo… Pls RT!
New research in @ScienceMagazine: Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition. Research co-led by @DanaFarber's William Freed-Pastor, MD, PhD, in collaboration with @MIT. Read more: bit.ly/4k9HyRW
Targeting resistance to RAS inhibition in pancreatic cancer: @DanaFarber's @andrewaguirremd presents in an #AACR25 session exploring advances in KRAS biology that may provide new therapeutic options for #PancreaticCancer. ➡️ bit.ly/4cYt3hx
Devastating!
FY25 funding for the Congressionally Directed Medical Research Program (@CDMRP ) to be cut by 57% from $1.5 billion to $650 million. 🚨🚨
🥼 Scientists at @DanaFarber, including @Nilay_Sethi, create a duel endogenous reporter system by editing the SOX9 and KRT20 loci of #ColorectalCancer cell lines to express fluorescent reporters. Follow 👣 the link to learn more! @NatureComms | 👉 go.nature.com/3x0DKix
Congratulations to @DanaFarber's William Freed-Pastor, MD, PhD, and Megan Insco, MD, PhD, @InscoLab for receiving the American Society for Clinical Investigation Young Investigator Award. Read about Dr. Freed-Pastor at bit.ly/41Kbu0R and Dr. Insco at…
The Trump administration's efforts to slash research funding have US graduate students, postdocs and other early-career scientists fearing for their careers. Some are considering changing jobs or leaving the country. Others say them might abandon research altogether.…
PhD programs are pausing admissions to graduate school due to NIH indirect cost cuts. See the growing number of programs here: docs.google.com/spreadsheets/d… How is science supposed to advance with fewer trainees, less $ for research? This is devastating.
Just heard that Vanderbilt rescinded all of its PhD offers because of NIH and NSF funding cuts and that Washington University St Louis is claiming that the STEM fields fund all the other depts and will be looking at cutting arts, etc.
“Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world.” -Louis Pasteur

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