Tewhey Lab @TewheyLab
Identifying the precise genetic mechanisms influencing human complex traits and disease risk at the @JacksonLab 🧬🐭💻✨ (tweets from students and post docs) tewheylab.org The Jackson Laboratory, ME Joined August 2022-
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@mainecalling's Patty Wight spoke with JAX researcher Ryan Tewhey (@TewheyLab) regarding his recent publication in @Nature. 📻 Listen to the coverage: mainepublic.org/health/2024-10… 💡 The study, published with the @broadinstitute of MIT and Harvard, and @Yale University, showcases…
Excited to share our sequence design work published in @Nature. I had the privilege of co-leading this effort alongside my friend and colleague @SagerGosai under the supervision of @r_tewhey, @ReillyLikesIt, and @PardisSabeti nature.com/articles/s4158… 1/7
I’m thrilled to share that our paper “Machine-guided design of cell-type-targeting cis-regulatory elements” was published online in @Nature. nature.com/articles/s4158… #genomics #MachineLearning #SyntheticBiology #bioengineering 1/9
Using #AI, a Broad/@jacksonlab /@YaleMed team has developed a way to decipher the language of genetic switches that turn genes on and off, and designed new, synthetic switches that control genes' expression in specific cell types. broad.io/CRE-AI @ReillyLikesIt
Happy National Postdoc Appreciation Week to Tewhey Lab post-doc @takeshi_iwasaki!! 🥳🎉 Takeshi is studying regulatory variants in autoimmune disease and is actually this year’s @jacksonlab JAX scholar!!🏆🧬 #NPAW2024
Yes Takeshi!!!! JAX Scholar and Tewhey Lab post doc @takeshi_iwasaki talks about his work in the lab ⬇️🧬
Yes Takeshi!!!! JAX Scholar and Tewhey Lab post doc @takeshi_iwasaki talks about his work in the lab ⬇️🧬
2024 JAX Scholar @takeshi_iwasaki discusses his work in the @TewheyLab identifying #genomicvariants and genetic mechanisms that influence #autoimmunedisease, and the importance of linking genetic variants to disease presentation or risk: bit.ly/3XGRDhi
Could not be more delighted to present our work investigating how over 220,000 complex and molecular trait-associated genetic variants affect transcriptional regulation using massively parallel reporter assays! biorxiv.org/content/10.110… See below for a 🧵. 1/n
#Postdoc job of the week: Join the @r_tewhey @TewheyLab to use novel, high-throughput techniques to study genetic mechanisms underlying complex traits, & the impact genetic variation has on gene regulatory function: …cksonlaboratory.wd1.myworkdayjobs.com/en-US/External… #Postdocs #Postdocjobs
This is by far the most convincing regulatory DNA synthetic design paper to date. Congrats to the authors 1/
This is by far the most convincing regulatory DNA synthetic design paper to date. Congrats to the authors 1/
SO happy this is live! See @SagerGosai tweet explaining our amazing collab with @i_rodcast, @r_tewhey, @PardisSabeti! TLDR: Used AI to learn to 'read' the genome's regulatory code and 'write' new, synthetic functions. Evolution didn't create this neuronal enhancer, but it works!
SO happy this is live! See @SagerGosai tweet explaining our amazing collab with @i_rodcast, @r_tewhey, @PardisSabeti! TLDR: Used AI to learn to 'read' the genome's regulatory code and 'write' new, synthetic functions. Evolution didn't create this neuronal enhancer, but it works! https://t.co/OWuC4JSUK6
Thank you!!! Honored to be a Tufts GSBS Rosenberg Fellow 🥳 Grateful for the nomination from my program and the endless support from my PI and lab ☺️ @r_tewhey @TewheyLab
Thank you!!! Honored to be a Tufts GSBS Rosenberg Fellow 🥳 Grateful for the nomination from my program and the endless support from my PI and lab ☺️ @r_tewhey @TewheyLab
I’m excited to share some work I co-lead with @i_rodcast and spanned the labs of @PardisSabeti, @ReillyLikesIt, and @r_tewhey to design and validate synthetic cis-regulatory elements with cell type-specific activity. biorxiv.org/content/10.110… 1/n
It’s official, the Twitter bio has been changed - ya girl’s a PhD candidate! 🥳 Grateful for all the support from my friends, family and committee! Super relieved to be done and even more ready for some of that Maine summer!! ☀️(Note: loading bar is not to scale…at all…)
New in @ScienceMagazine, JAX's @r_tewhey @TewheyLab & colleagues I.D. 800 human-specific conserved deletions (hCONDELS) that confer significant differences in regulatory activity, highlighting several with putative effects on brain development: jax.org/news-and-insig…
New in @ScienceMagazine, JAX's @r_tewhey @TewheyLab & colleagues I.D. 800 human-specific conserved deletions (hCONDELS) that confer significant differences in regulatory activity, highlighting several with putative effects on brain development: jax.org/news-and-insig…
Getting emotional about friendship and an ice bucket on a Thursday. 🥲🧊
Getting emotional about friendship and an ice bucket on a Thursday. 🥲🧊
#Postdoc job of the week: Join the @r_tewhey @TewheyLab to use novel, high-throughput techniques to study genetic mechanisms underlying complex traits, & the impact genetic variation has on gene regulatory function: …cksonlaboratory.wd1.myworkdayjobs.com/en-US/External… #Postdocs #Postdocjobs #sciencetwitter
Congratulations!! Kousuke's talk at @IMGC2023_sec was based on his paper on genetic variants of regulatory elements in autoimmune disease. Read Kousuke's BACH2 paper here: nature.com/articles/s4158…
Congratulations!! Kousuke's talk at @IMGC2023_sec was based on his paper on genetic variants of regulatory elements in autoimmune disease. Read Kousuke's BACH2 paper here: nature.com/articles/s4158…
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