Chi Celest @The_Chis_lab
protein-protein/small molecule interaction, protein structure determination, NMR, IDP scholar.google.ch/citations?hl=e… Uppsala, Sverige Joined October 2017-
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Allosteric regulation is historically associated with multi-domain proteins. However, in recent times, allosteric regulation has been increasingly attributed to small-single domain proteins. Here, in our new publication #NatCom rdcu.be/cXXP8.
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Here is my all-time Premier League XI - who would you pick? team-picker.files.bbci.co.uk/all-time-premi… #MyPremierLeagueXI via @bbcsport
Check out this job from AstraZeneca linkedin.com/jobs/view/3158…
Chi Celest retweeted
. @microbiologyOA (open) New strategy for producing membrane proteins in native vesicles without unfolding and refolding in detergents that often affect their architecture, Mohammed Mouhib, Celestine N. Chi* @The_Chis_lab onlinelibrary.wiley.com/doi/10.1002/mb… #NMRchat #NMR
It is now widely accepted that the Eukaryotes emerged from within the Asgard clade. A new paper (lnkd.in/eq_6sE89) from my lab published in Advanced Biology further ascertained this claim and showed that the Thorarchaeota encodes profilins that coexpress in eukaryotic cell
Ever wondered how evolution influence the structure and dynamics of intrinsically disordered proteins? Check out our new finding which tries to answer just that! Published today in communications biology #nature #communication biology nature.com/articles/s4200…
@8rownF0X @EricTopol And this is contradictory to the idea of selection fit variant selection in immune compromised individuals
@8rownF0X @EricTopol Viruses mutate all the time and in a system good immune response the virus will be challenged and only very efficient ones will survive hence fit variants. In the other hand if the immune system is compromised there is less pressure and no need for selection
New role in drug discovery @AstraZeneca starting spring as a senior scientist/ biomolecular @nmr specialist. New discoveries in the pipeline!! Exciting times ahead!
Chi Celest retweeted
My first first-author research article is now published in PNAS! 🎉🥂 pnas.org/content/118/47…
@PetzoldKatja Congratulations @PetzoldKatja
Chi Celest retweeted
We introduced a protocol for Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance which unravels an allosteric pathway. #NMR #EPR @CUAnschutz @CUCancerCenter
Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance pubs.acs.org/doi/10.1021/ja…
@Corp_Raider99 @canardbruno @ElisaTelisa @SFV_France @Ayjchan @Dj0gil @DecrolyE @FRM_officiel @sfoucart @jbloom_lab @ProfPaulYoung @yvessciama @ydeigin The good thing with a conspiracy is that it can take any direction and the perpetrators will always shout victory ✌️
Thanks to @AndreaBenedikt1 for synthesising the detergents
Just out! We @The_Chis_lab show that it is important to carefully evaluate “Detergent and Lipid Composition for Structural Studies as they may influence the structural integrity of Reconstituted Membrane Proteins “ pubs.acs.org/doi/10.1021/ac…
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