Markus Zweckstetter @mz_science
Joined August 2018-
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Markus Zweckstetter retweeted
Interested in translational science? 🧪 Our team at #DZNE Munich is seeking a technician for the GA-VAX project. Your work could directly contribute to clinical trials with #C9orf72 #ALS patients. Apply now and join our team! #Jobs #Research jobs.dzne.de/de/jobs/101347…
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Markus Zweckstetter retweeted
Check out the enticing and diverse Scientific Program of #SMASH2024 (Burlington, VT, USA - September 15-18, 2024) put together by @tkfarley1 Kathleen Farley and myself, the Program Chairs. We've assembled seven sessions, two workshops, led by 17 speakers. smashnmr.org
An enormous thank you to my fantastic team, co-workers, collaborators and the European Union for making this possible , and my Kids Magdalena and Maximilian for their inspiration. dzne.de/en/news/press-…
Markus Zweckstetter retweeted
This is a major milestone for the diagnosis and treatment of Alzheimer’s. The ptau-217 blood test is shown to be as accurate as CSF and PET, making diagnosis far more accessible. And detecting AD before observable symptoms will enable much earlier intervention.
This is a major milestone for the diagnosis and treatment of Alzheimer’s. The ptau-217 blood test is shown to be as accurate as CSF and PET, making diagnosis far more accessible. And detecting AD before observable symptoms will enable much earlier intervention.
Markus Zweckstetter retweeted
In a just published article in #NatureComms, we report droplet formation by an RG-rich fragment of coilin, a protein acting as the scaffold of Cajal bodies (CBs). CBs are highly dynamic nuclear bodies with rapid component exchange, supporting RNA splicing. link.springer.com/article/10.103…
Very much looking forward to this exciting meeting!
Very much looking forward to this exciting meeting!
Pat, did you get my email?
Markus Zweckstetter retweeted
Comparison of four transcription elongation factors reveals conserved regulatory mechanisms. New review by @YingChen_P sciencedirect.com/science/articl…
Congratulations Samrat!
Markus Zweckstetter retweeted
Dear international students and talents from around the world, note that German universities welcome foreign students, are tuition free and many subjects are taught in English. Germany has become an open and liberal society in contrast to what the UK government is implementing.
Dear international students and talents from around the world, note that German universities welcome foreign students, are tuition free and many subjects are taught in English. Germany has become an open and liberal society in contrast to what the UK government is implementing.
Ending 2023 in style: Hsp90-Independent cochaperone-mediated regulation of Tau aggregation: fantastic work from Pijush Chakraborty doi.org/10.1101/2023.1…
Thanks Sjors. This is how good we could get the structure with the available data.
Markus Zweckstetter retweeted
ICMRBS 2024 the 30th International Conference on Magnetic Resonance in Biological Systems (ICMRBS 2024) | August 18 (Sun) - 23 (Fri), 2024 | Coex, Seoul, Korea icmrbs2024.org/main/bbs_news_… #NMRevents #NMRchat #NMR
Good point. We see (i) that GSK3b phosphorylation accelerates aging of tau condensates and (ii) fibrils of unphosphorylated tau have a different morphology, suggesting that the GSK3b phosphorylation is critical.
Good point. We see (i) that GSK3b phosphorylation accelerates aging of tau condensates and (ii) fibrils of unphosphorylated tau have a different morphology, suggesting that the GSK3b phosphorylation is critical.
A direct link between Tau phosphorylation by GSK3beta, #Tau condensation and #AlzheimersDisease 's Disease Tau Fold: stellar work from Pijush Chakraborty in collaboration with the lab of Ben Wolozin biorxiv.org/content/10.110…
Tina Ukmar-Godec and coworkers from my lab show in a collaboration with the @fischle_lab that phase separation of human HP1alpha is not necessary to compact chromatin
Tina Ukmar-Godec and coworkers from my lab show in a collaboration with the @fischle_lab that phase separation of human HP1alpha is not necessary to compact chromatin
Markus Zweckstetter retweeted
Vielen Dank for the speech, rooted in knowledge and striking a well-balanced yet comprehensive, clear and empathetic tone. Such leadership gives hope for a unified stance among all nationalities to renounce hatred and embrace the greater good.
Vielen Dank for the speech, rooted in knowledge and striking a well-balanced yet comprehensive, clear and empathetic tone. Such leadership gives hope for a unified stance among all nationalities to renounce hatred and embrace the greater good.
Markus Zweckstetter retweeted
Saddened to hear of the passing of Tony Keller aged 86, a pioneer in NMR technology and former director of @bruker and co-CEO of Bruker BioSpin. Tony was a great supporter and friend to many in the #NMR field and we will miss him. #biophysics #chemistry bruker.com/en/news-and-ev…
What is the connection between synaptic dysfunction in #AlzheimersDisease and #Tau? PhD student Zheng Shen in collaboration with the lab of Alf Honigmann shows that Tau induces changes in the material properties of post-synaptic density #condensates nature.com/articles/s4146….
Markus Zweckstetter retweeted
Acetylation fuels aggregation of three-repeat tau yet slows that of four-repeat tau. Why? Acetylated lysines in a segment unique to 4R tau disrupt fibril cores. @DZNE_en ow.ly/bbRK50PUbkb
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149 Followers 883 Following Demenz in jungen Jahren… ICH HABE DEMENZ…KEINE ANGST, IST NICHT ANSTECKEND#Autorin/Demenzaktivistin Selbstbetroffene FTD Parkinson /Diversity On Kooperation
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3K Followers 491 Following #MolecularSociology @MPIbp @becklab.bsky.social
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